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相关论文: Open-source neuronavigation for multimodal non-inv…

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Transcranial focused ultrasound (FUS) is a non-invasive technique for therapy and study of brain neural activation. Here we report on the design and characterization of a new MR-guided FUS transducer for neuromodulation in non-human…

医学物理 · 物理学 2018-06-13 Vandiver Chaplin , Marshal A. Phipps , Charles F. Caskey

Low-intensity transcranial focused ultrasound (tFUS) is rapidly emerging as a transformative non-invasive brain stimulation (NIBS) modality characterized by high spatial resolution and ability to target deep brain circuits. Unlike…

神经元与认知 · 定量生物学 2026-04-02 William J. Tyler

Accurate neuronavigation is critical for effective transcranial magnetic stimulation (TMS), as stimulation outcomes depend directly on precise coil placement. Existing neuronavigation systems are often costly, complex, and prone to tracking…

人机交互 · 计算机科学 2026-01-26 Xuyi Hu , Ke Ma , Siwei Liu , Per Ola Kristensson , Stefan Goetz

Robot-assisted Transcranial Magnetic Stimulation (Robo-TMS) is an image-guided robotic intervention that enhances the accuracy and reproducibility of conventional Transcranial Magnetic Stimulation (TMS), a widely used non-invasive brain…

机器人学 · 计算机科学 2026-04-29 Wenzhi Bai , Yituo Guo , Bhaskar Basu , Andrew Weightman , Zhenhong Li

Transcranial focused ultrasound (tFUS) is an emerging form of non-surgical human neuromodulation that confers advantages over existing electro and electromagnetic technologies by providing a superior spatial resolution on the millimeter…

神经元与认知 · 定量生物学 2016-03-02 Leo Ai , Jerel K. Mueller , Andrea Grant , Yigitcan Eryaman , Wynn Legon

High precision neuromodulation is a powerful tool to decipher neurocircuits and treat neurological diseases. Current non-invasive neuromodulation methods offer limited precision at the millimeter level. Here, we report optically-generated…

神经元与认知 · 定量生物学 2022-11-07 Yueming Li , Ying Jiang , Lu Lan , Xiaowei Ge , Ran Cheng , Yuewei Zhan , Guo Chen , Linli Shi , Runyu Wang , Nan Zheng , Chen Yang , Ji-Xin Cheng

Accurate neuronavigation is essential for generating the intended effect with transcranial magnetic stimulation (TMS). Precise coil placement also directly influences stimulation efficacy. Traditional neuronavigation systems often rely on…

人机交互 · 计算机科学 2026-01-29 Xuyi Hu , Ke Ma , Siwei Liu , Per Ola Kristensson , Stephan Goetz

We present a real-time visualization system for Transcranial Magnetic Stimulation (TMS), a non-invasive neuromodulation technique for treating various brain disorders and mental health diseases. Our solution targets the current challenges…

信号处理 · 电气工程与系统科学 2024-03-14 Loraine Franke , Tae Young Park , Jie Luo , Yogesh Rathi , Steve Pieper , Lipeng Ning , Daniel Haehn

Identifying what aspects of brain activity are responsible for conscious perception remains one of the most challenging problems in science. While progress has been made through psychophysical studies employing EEG and fMRI, research would…

神经元与认知 · 定量生物学 2025-07-14 Daniel K. Freeman , Brian Odegaard , Seung-Schik Yoo , Matthias Michel

Low-intensity Transcranial Ultrasonic Stimulation (TUS) is a non-invasive brain stimulation technique enabling cortical and deep brain targeting with unprecedented spatial accuracy. Given the high rate of adoption by new users with varying…

For decades, focal non-invasive neuromodulation of deep brain regions has not been possible because of the steep depth-focality trade-off of conventional non-invasive brain stimulation (NIBS) techniques, such as transcranial magnetic…

神经元与认知 · 定量生物学 2025-12-17 Pierre Vassiliadis , Elena Beanato , Maximilian J. Wessel , Friedhelm C. Hummel

Closed-loop brain stimulation refers to capturing neurophysiological measures such as electroencephalography (EEG), quickly identifying neural events of interest, and producing auditory, magnetic or electrical stimulation so as to interact…

信号处理 · 电气工程与系统科学 2022-10-12 Nicolas Valenchon , Yann Bouteiller , Hugo R. Jourde , Xavier L'Heureux , Milo Sobral , Emily B. J. Coffey , Giovanni Beltrame

Fully immersive virtual reality (VR) has the potential to improve neurosurgical planning. For example, it may offer 3D visualizations of relevant anatomical structures with complex shapes, such as blood vessels and tumors. However, there is…

人机交互 · 计算机科学 2019-08-15 Lukas D. J. Fiederer , Hisham Alwanni , Martin Völker , Oliver Schnell , Jürgen Beck , Tonio Ball

Neuronavigation is widely used in biomedical research and interventions to guide the precise placement of instruments around the head to support procedures such as transcranial magnetic stimulation. Traditional systems, however, rely on…

Transcranial focused ultrasound (tFUS) is an emerging modality for non-invasive brain stimulation and therapeutic intervention, offering millimeter-scale spatial precision and the ability to target deep brain structures. However, the…

计算机视觉与模式识别 · 计算机科学 2025-05-20 Vinkle Srivastav , Juliette Puel , Jonathan Vappou , Elijah Van Houten , Paolo Cabras , Nicolas Padoy

Background: Trans-spinal FUS (tsFUS) has recently been shown promise in modulating spinal reflexes in rodents, opening new avenues for spinal cord interventions in motor control and pain management. However, anatomical differences between…

医学物理 · 物理学 2025-07-09 Koharu Isomura , Wenwei Yu , Jose Gomez-Tames

A significant and rising proportion of the global population suffer from non-communicable diseases, such as neurological disorders. Neurorehabilitation aims to restore function and independence of neurological patients through providing…

Non-invasive stimulation of small, variably shaped brain sub-regions is crucial for advancing our understanding of brain functions. Current ultrasound neuromodulation faces two significant trade-offs when targeting brain sub-regions:…

Focused ultrasound (FUS) therapy is a promising tool for optimally targeted treatment of spinal cord injuries (SCI), offering submillimeter precision to enhance blood flow at injury sites while minimizing impact on surrounding tissues.…

医学物理 · 物理学 2024-12-23 Avisha Kumar , Xuzhe Zhi , Zan Ahmad , Minglang Yin , Amir Manbachi

Neuromorphic systems open up opportunities to enlarge the explorative space for computational research. However, it is often challenging to unite efficiency and usability. This work presents the software aspects of this endeavor for the…

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