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Threshold selection is a fundamental problem in any threshold-based extreme value analysis. While models are asymptotically motivated, selecting an appropriate threshold for finite samples is difficult and highly subjective through standard…

统计方法学 · 统计学 2024-10-30 Conor Murphy , Jonathan A. Tawn , Zak Varty

In this paper, a Mixed Data Sampling (MIDAS) model is studied when both low and high frequency variables are contaminated with measurement error. It is shown that the profile likelihood estimator becomes inconsistent in the presence of…

统计方法学 · 统计学 2026-04-28 Sukhbir Kaur , Sukhbir Singh , Kanchan Jain , Pooja Soni

Measurement error arises through a variety of mechanisms. A rich literature exists on the bias introduced by covariate measurement error and on methods of analysis to address this bias. By comparison, less attention has been given to errors…

统计方法学 · 统计学 2018-11-27 Pamela Shaw , Jiwei He , Bryan Shepherd

Supervised classifying of biological samples based on genetic information, (e.g. gene expression profiles) is an important problem in biostatistics. In order to find both accurate and interpretable classification rules variable selection is…

统计方法学 · 统计学 2012-08-09 Bernd Klaus

We propose new methods for multivariate linear regression when the regression coefficient matrix is sparse and the error covariance matrix is dense. We assume that the error covariance matrix has equicorrelation across the response…

统计方法学 · 统计学 2025-08-13 Daeyoung Ham , Bradley S. Price , Adam J. Rothman

We propose an iterative variable selection method for the accelerated failure time model using high-dimensional survival data. Our method pioneers the use of the recently proposed structured screen-and-select framework for survival…

统计方法学 · 统计学 2025-03-04 Nilotpal Sanyal

Competing risk analysis considers event times due to multiple causes, or of more than one event types. Commonly used regression models for such data include 1) cause-specific hazards model, which focuses on modeling one type of event while…

应用统计 · 统计学 2017-04-27 Jiayi Hou , Anthony Paravati , Ronghui Xu , James Murphy

Microarray studies, in order to identify genes associated with an outcome of interest, usually produce noisy measurements for a large number of gene expression features from a small number of subjects. One common approach to analyzing such…

统计方法学 · 统计学 2021-04-21 Linh Nghiem , Francis K. C. Hui , Samuel Mueller , A. H. Welsh

Variable selection is of increasing importance to address the difficulties of high dimensionality in many scientific areas. In this paper, we demonstrate a property for distance covariance, which is incorporated in a novel feature screening…

统计方法学 · 统计学 2014-09-03 Jing Kong , Sijian Wang , Grace Wahba

With the availability of high dimensional genetic biomarkers, it is of interest to identify heterogeneous effects of these predictors on patients' survival, along with proper statistical inference. Censored quantile regression has emerged…

统计方法学 · 统计学 2021-07-26 Zhe Fei , Qi Zheng , Hyokyoung G. Hong , Yi Li

Excess hazard modeling is one of the main tools in population-based cancer survival research. Indeed, this setting allows for direct modeling of the survival due to cancer even in the absence of reliable information on the cause of death,…

统计方法学 · 统计学 2022-04-12 A. Eletti , G. Marra , M. Quaresma , R. Radice , F. J. Rubio

We introduce a novel Bayesian approach for both covariate selection and sparse precision matrix estimation in the context of high-dimensional Gaussian graphical models involving multiple responses. Our approach provides a sparse estimation…

统计方法学 · 统计学 2024-09-25 Anwesha Chakravarti , Naveen N. Narishetty , Feng Liang

Recently, there as been an increasing interest in the use of heavily restricted randomization designs which enforces balance on observed covariates in randomized controlled trials. However, when restrictions are strict, there is a risk that…

统计方法学 · 统计学 2021-10-15 Mattias Nordin , Mårten Schultzberg

Selection of covariates is crucial in the estimation of average treatment effects given observational data with high or even ultra-high dimensional pretreatment variables. Existing methods for this problem typically assume sparse linear…

统计方法学 · 统计学 2023-03-20 Juan Chen , Yingchun Zhou

Individualized treatment rules can lead to better health outcomes when patients have heterogeneous responses to treatment. Very few individualized treatment rule estimation methods are compatible with a multi-treatment observational study…

统计方法学 · 统计学 2019-11-14 Owen E. Leete , Nathan Kallus , Michael G. Hudgens , Sonia Napravnik , Michael R. Kosorok

Epidemiologic studies often evaluate the association between an exposure and an event risk. When time-varying, exposure updates usually occur at discrete visits although changes are in continuous time and survival models require values to…

We consider a Gaussian sequence space model $X_{\lambda}=f_{\lambda} + \xi_{\lambda},$ where $\xi $ has a diagonal covariance matrix $\Sigma=\diag(\sigma_\lambda ^2)$. We consider the situation where the parameter vector $(f_{\lambda})$ is…

统计理论 · 数学 2013-12-23 Laurent Cavalier , Markus Reiß

Kaplan-Meier survival analysis represents the most objective measure of treatment efficacy in oncology, though subjected to potential bias, which is worrisome in an era of precision medicine. Independent of the bias inherent to the design…

统计方法学 · 统计学 2020-12-17 Enrique Barrajón , Laura Barrajón

Accurate time-to-event prediction is integral to decision-making, informing medical guidelines, hiring decisions, and resource allocation. Survival analysis, the quantitative framework used to model time-to-event data, accounts for patients…

机器学习 · 计算机科学 2025-08-08 Vincent Jeanselme , Brian Tom , Jessica Barrett

Variable selection in linear regression models has been a problem since hypothesis testing began. Which variables to include or exclude from a model is not an easy task. Techniques such as Forward, Back ward, Stepwise Regression…

统计方法学 · 统计学 2026-05-01 By Riyadh Alrawkan , Edward Boone , Ryad Ghanam , Anton Westveld