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In genetical genomics studies, it is important to jointly analyze gene expression data and genetic variants in exploring their associations with complex traits, where the dimensionality of gene expressions and genetic variants can both be…

统计方法学 · 统计学 2014-04-15 Wei Lin , Rui Feng , Hongzhe Li

Truncation is a statistical phenomenon that occurs in many time to event studies. For example, autopsy-confirmed studies of neurodegenerative diseases are subject to an inherent left and right truncation, also known as double truncation.…

统计方法学 · 统计学 2018-03-28 Lior Rennert , Sharon X. Xie

The purpose of this work is to improve the efficiency in estimating the average causal effect (ACE) on the survival scale where right-censoring exists and high-dimensional covariate information is available. We propose new estimators using…

统计方法学 · 统计学 2021-06-29 Ran Dai , Cheng Zheng , Mei-Jie Zhang

Autocovariance of the error term in a time series model plays a key role in the estimation and inference for the model that it belongs to. Typically, some arbitrary parametric structure is assumed upon the error to simplify the estimation,…

统计方法学 · 统计学 2022-10-17 Yoon Bae Jun , Chae Young Lim , Kun Ho Kim

Two problems that arise in making causal inferences for non-mortality outcomes such as bronchopulmonary dysplasia (BPD) are unmeasured confounding and censoring by death, i.e., the outcome is only observed when subjects survive. In…

统计方法学 · 统计学 2018-02-20 Kwonsang Lee , Scott A. Lorch , Dylan S. Small

Recent literature provides many computational and modeling approaches for covariance matrices estimation in a penalized Gaussian graphical models but relatively little study has been carried out on the choice of the tuning parameter. This…

统计方法学 · 统计学 2009-09-08 Heng Lian

When dealing with right-censored data, where some outcomes are missing due to a limited observation period, survival analysis -- known as time-to-event analysis -- focuses on predicting the time until an event of interest occurs. Multiple…

Meta-analysis is a well-established method for integrating results from several independent studies to estimate a common quantity of interest. However, meta-analysis is prone to selection bias, notably when particular studies are…

应用统计 · 统计学 2024-11-20 Layna Charlie Dennett , Antony Overstall , Dankmar Boehning

The analysis of a truncated sample can be hindered by censoring. Survival information may be lost to follow-up or the birthdate may be missing. The data can still be modeled as a truncated point process and it is close to a Poisson process,…

统计方法学 · 统计学 2025-08-12 Fiete Sieg , Anne-Marie Toparkus , Rafael Weissbach

High dimensional statistical problems arise from diverse fields of scientific research and technological development. Variable selection plays a pivotal role in contemporary statistical learning and scientific discoveries. The traditional…

统计理论 · 数学 2009-10-08 Jianqing Fan , Jinchi Lv

Competing risks data refer to situations where the occurrence of one event pre- cludes the possibility of other events happening, resulting in multiple mutually exclusive events. This data type is commonly encountered in medical research…

统计方法学 · 统计学 2025-10-21 Fatemeh Mahmoudi , Chenxi Li , Kaida Cai , Xuewen Lu

This paper considers one-step targeted maximum likelihood estimation method for general competing risks and survival analysis settings where event times take place on the positive real line R+ and are subject to right-censoring. Our…

统计方法学 · 统计学 2021-09-02 Helene C. W. Rytgaard , Mark J. van der Laan

We address the problem of providing inference from a Bayesian perspective for parameters selected after viewing the data. We present a Bayesian framework for providing inference for selected parameters, based on the observation that…

统计计算 · 统计学 2015-03-13 Daniel Yekutieli

In medical settings, treatment assignment may be determined by a clinically important covariate that predicts patients' risk of event. There is a class of methods from the social science literature known as regression discontinuity (RD)…

统计方法学 · 统计学 2019-08-13 Youngjoo Cho , Chen Hu , Debashis Ghosh

This paper provides an alternative to penalized estimators for estimation and vari- able selection in high dimensional linear regression models with measurement error or missing covariates. We propose estimation via bias corrected least…

统计方法学 · 统计学 2016-05-11 Abhishek Kaul , Hira L. Koul , Akshita Chawla , Soumendra N. Lahiri

Tree methods (recursive partitioning) are a popular class of nonparametric methods for analyzing data. One extension of the basic tree methodology is the survival tree, which applies recursive partitioning to censored survival data. There…

统计方法学 · 统计学 2017-03-01 Wei Fu , Jeffrey S. Simonoff

We present a general principle for estimating a regression function nonparametrically, allowing for a wide variety of data filtering, for example, repeated left truncation and right censoring. Both the mean and the median regression cases…

统计理论 · 数学 2011-02-10 Oliver Linton , Enno Mammen , Jens Perch Nielsen , Ingrid Van Keilegom

In many important statistical analyses, the number of covariates $p$ often exceeds the data size $n$, a regime commonly referred to as high-dimensional. While considerable progress has been made in high-dimensional regression under the…

统计方法学 · 统计学 2026-05-29 Herman Tesso , Georges Nguefack-Tsague

We introduce a flexible individual frailty model for clustered right-censored data, in which covariate effects can be marginally interpreted as log failure odds ratios. Flexible correlation structures can be imposed by introducing…

统计方法学 · 统计学 2014-03-27 Rui Zhang Kwun Chuen Gary Chan

The effectiveness of non-parametric, kernel-based methods for function estimation comes at the price of high computational complexity, which hinders their applicability in adaptive, model-based control. Motivated by approximation techniques…

统计理论 · 数学 2023-03-17 Anna Scampicchio , Elena Arcari , Melanie N. Zeilinger