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Molecular signaling networks are believed to determine cancer robustness. Although cancer patient survivability was reported to correlate with the heterogeneous connectivity of the signaling networks inspired by theoretical studies on the…

分子网络 · 定量生物学 2013-07-18 Kazuhiro Takemoto , Kaori Kihara

In this work, we propose to use a local clustering approach based on the sparse solution technique to study the medical image, especially the lung cancer image classification task. We view images as the vertices in a weighted graph and the…

计算机视觉与模式识别 · 计算机科学 2025-05-22 Jackson Hamel , Ming-Jun Lai , Zhaiming Shen , Ye Tian

Lung cancer is one of the prevalence diseases in the world which cause many deaths. Detecting early stages of lung cancer is so necessary. So, modeling and simulating some intelligent medical systems is an essential which can help…

图像与视频处理 · 电气工程与系统科学 2023-12-07 Ehsan Sadeghi Pour , Mahdi Esmaeili

While we once thought of cancer as single monolithic diseases affecting a specific organ site, we now understand that there are many subtypes of cancer defined by unique patterns of gene mutations. These gene mutational data, which can be…

定量方法 · 定量生物学 2017-03-07 Jipeng Qiang , Wei Ding , John Quackenbush , Ping Chen

Cystic fibrosis is a genetic disease which may appear in early life with structural abnormalities in lung tissues. We propose to detect these abnormalities using a texture classification approach. Our method is a cascade of two…

计算机视觉与模式识别 · 计算机科学 2018-03-22 Filipe Marques , Florian Dubost , Mariette Kemner-van de Corput , Harm A. W. Tiddens , Marleen de Bruijne

The recent development of imaging and sequencing technologies enables systematic advances in the clinical study of lung cancer. Meanwhile, the human mind is limited in effectively handling and fully utilizing the accumulation of such…

机器学习 · 计算机科学 2022-03-29 Yawei Li , Xin Wu , Ping Yang , Guoqian Jiang , Yuan Luo

Aim: Early detection and correct diagnosis of lung cancer are the most important steps in improving patient outcome. This study aims to assess which deep learning models perform best in lung cancer diagnosis. Methods: Non-small cell lung…

计算机视觉与模式识别 · 计算机科学 2018-03-16 Zhang Li , Zheyu Hu , Jiaolong Xu , Tao Tan , Hui Chen , Zhi Duan , Ping Liu , Jun Tang , Guoping Cai , Quchang Ouyang , Yuling Tang , Geert Litjens , Qiang Li

Image classification is widely used to build predictive models for breast cancer diagnosis. Most existing approaches overwhelmingly rely on deep convolutional networks to build such diagnosis pipelines. These model architectures, although…

图像与视频处理 · 电气工程与系统科学 2022-01-20 Alireza Rezazadeh , Yasamin Jafarian , Ali Kord

Studies have shown that the traces people leave when browsing the internet may indicate the onset of diseases such as cancer. Here we show that the adaptive engines of advertising systems in conjunction with clinically verified…

计算机与社会 · 计算机科学 2018-08-09 Elad Yom-Tov

Lung cancer is the leading cause of cancer-related death worldwide. Early diagnosis of pulmonary nodules in Computed Tomography (CT) chest scans provides an opportunity for designing effective treatment and making financial and care plans.…

计算机视觉与模式识别 · 计算机科学 2018-06-19 Raunak Dey , Zhongjie Lu , Yi Hong

Lung cancer (LC) remains the primary cause of cancer-related mortality, largely due to late-stage diagnoses. Effective strategies for early detection are therefore of paramount importance. In recent years, machine learning (ML) has…

Radiomics has proven to be a powerful prognostic tool for cancer detection, and has previously been applied in lung, breast, prostate, and head-and-neck cancer studies with great success. However, these radiomics-driven methods rely on…

计算机视觉与模式识别 · 计算机科学 2015-11-12 Mohammad Javad Shafiee , Audrey G. Chung , Devinder Kumar , Farzad Khalvati , Masoom Haider , Alexander Wong

One of the deadliest cancers, lung cancer necessitates an early and precise diagnosis. Because patients have a better chance of recovering, early identification of lung cancer is crucial. This review looks at how to diagnose lung cancer…

机器学习 · 计算机科学 2025-01-22 Omid Shahriyar , Babak Nuri Moghaddam , Davoud Yousefi , Abbas Mirzaei , Farnaz Hoseini

Identifying latent structure in large data matrices is essential for exploring biological processes. Here, we consider recovering gene co-expression networks from gene expression data, where each network encodes relationships between genes…

统计方法学 · 统计学 2014-11-10 Chuan Gao , Shiwen Zhao , Ian C. McDowell , Christopher D. Brown , Barbara E. Engelhardt

We performed a gene co-expression analysis on Lung Squamous Cell Carcinoma data to find modules (groups) of genes that may highly impact the growth of these type of tumors. Additionally, we used cancer survival data to relate modules to…

基因组学 · 定量生物学 2018-04-05 Md-Nafiz Hamid

Can a single label-free image reveal whether cancer cells were exposed to chemotherapy? We present an innovative methodology on the label-free and high-resolution imaging properties of phase holotomographic microscopy coupled with neural…

Lung cancer is one of the most commonly diagnosed cancers, and early diagnosis is critical because the survival rate declines sharply once the disease progresses to advanced stages. However, achieving an early diagnosis remains challenging,…

计算机视觉与模式识别 · 计算机科学 2025-11-25 Yutong Wu , Yifan Wang , Qining Zhang , Chuan Zhou , Lei Ying

Due to its predominantly asymptomatic or mildly symptomatic progression, lung cancer is often diagnosed in advanced stages, resulting in poorer survival rates for patients. As with other cancers, early detection significantly improves the…

Early detection of lung cancer is critical to improving survival outcomes. We present a deep learning framework for automated lung cancer screening from chest computed tomography (CT) images with integrated explainability. Using the…

图像与视频处理 · 电气工程与系统科学 2026-01-07 Nishan Rai , Sujan Khatri , Devendra Risal

Cancer is increasingly perceived as a systems-level, network phenomenon. The major trend of malignant transformation can be described as a two-phase process, where an initial increase of network plasticity is followed by a decrease of…