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The doubly robust estimator, which models both the propensity score and outcomes, is a popular approach to estimate the average treatment effect in the potential outcome setting. The primary appeal of this estimator is its theoretical…

统计方法学 · 统计学 2024-09-11 Kaoru Babasaki , Shonosuke Sugasawa , Kosaku Takanashi , Kenichiro McAlinn

We overview Bayesian estimation, hypothesis testing, and model-averaging and illustrate how they benefit parametric survival analysis. We contrast the Bayesian framework to the currently dominant frequentist approach and highlight…

统计方法学 · 统计学 2022-09-13 František Bartoš , Frederik Aust , Julia M. Haaf

In recent years, mixture cure models have gained increasing popularity in survival analysis as an alternative to the Cox proportional hazards model, particularly in settings where a subset of patients is considered cured. The proportional…

统计方法学 · 统计学 2025-12-10 Fatih Kızılaslan , Valeria Vitelli

The paper describes the use of Bayesian regression for building time series models and stacking different predictive models for time series. Using Bayesian regression for time series modeling with nonlinear trend was analyzed. This approach…

应用统计 · 统计学 2022-01-07 Bohdan M. Pavlyshenko

Frailty models are essential tools in survival analysis for addressing unobserved heterogeneity and random effects in the data. These models incorporate a random effect, the frailty, which is assumed to impact the hazard rate…

统计理论 · 数学 2025-04-01 Jorge Yslas

Conventional survival analysis approaches estimate risk scores or individualized time-to-event distributions conditioned on covariates. In practice, there is often great population-level phenotypic heterogeneity, resulting from (unknown)…

机器学习 · 统计学 2020-03-03 Paidamoyo Chapfuwa , Chunyuan Li , Nikhil Mehta , Lawrence Carin , Ricardo Henao

A Bayesian non-parametric framework for studying time-to-event data is proposed, where the prior distribution is allowed to depend on an additional random source, and may update with the sample size. Such scenarios are natural, for…

统计方法学 · 统计学 2025-05-06 Martin Bladt , Jorge González Cázares

An adaptive design adjusts dynamically as information is accrued and a consequence of applying an adaptive design is the potential for inducing small-sample bias in estimates. In psychometrics and psychophysics, a common class of studies…

统计方法学 · 统计学 2025-02-17 Simon Bang Kristensen , Katrine Bødkergaard , Bo Martin Bibby

This paper deals with unobserved heterogeneity in the survival dataset through Accelerated Failure Time (AFT) models under both frameworks--Bayesian and classical. The Bayesian approach of dealing with unobserved heterogeneity has recently…

应用统计 · 统计学 2017-09-12 Shaila Sharmin , Md Hasinur Rahaman Khan

Count outcomes in longitudinal studies are frequent in clinical and engineering studies. In frequentist and Bayesian statistical analysis, methods such as Mixed linear models allow the variability or correlation within individuals to be…

统计方法学 · 统计学 2024-07-15 Alejandra Estefanía Patiño Hoyos , Johnatan Cardona Jiménez

We develop a nonparametric Bayesian modeling framework for clustered ordinal responses in developmental toxicity studies, which typically exhibit extensive heterogeneity. The primary focus of these studies is to examine the dose-response…

统计方法学 · 统计学 2024-08-22 Jizhou Kang , Athanasios Kottas

Many phase II clinical trials have used survival outcomes as the primary endpoints in recent decades. Suppose the radiotherapy is evaluated in a phase II trial using survival outcomes. In that case, the competing risk issue often arises…

应用统计 · 统计学 2022-03-15 Jina Park , Wenjing Hu , Ick Hoon Jin , Hao Liu , Yong Zang

Humans are routinely exposed to mixtures of chemical and other environmental factors, making the quantification of health effects associated with environmental mixtures a critical goal for establishing environmental policy sufficiently…

For estimating conditional survival functions, non-parametric estimators can be preferred to parametric and semi-parametric estimators due to relaxed assumptions that enable robust estimation. Yet, even when misspecified, parametric and…

统计方法学 · 统计学 2014-12-23 Andrew Wey , John Connett , Kyle Rudser

Survival analysis is an important area of medical research, yet existing models often struggle to balance simplicity with flexibility. Simple models require minimal adjustments but come with strong assumptions, while more flexible models…

统计方法学 · 统计学 2025-08-22 Peter Knaus , Daniel Winkler , Sebastian F. Schoppmann , Gerd Jomrich

This tutorial shows how various Bayesian survival models can be fitted using the integrated nested Laplace approximation in a clear, legible, and comprehensible manner using the INLA and INLAjoint R-packages. Such models include accelerated…

统计方法学 · 统计学 2024-03-19 Danilo Alvares , Janet van Niekerk , Elias Teixeira Krainski , Håvard Rue , Denis Rustand

There is increasing interest in flexible parametric models for the analysis of time-to-event data, yet Bayesian approaches that offer incorporation of prior knowledge remain underused. A flexible Bayesian parametric model has recently been…

There is wide interest in studying how the distribution of a continuous response changes with a predictor. We are motivated by environmental applications in which the predictor is the dose of an exposure and the response is a health…

统计方法学 · 统计学 2018-05-10 Antonio Canale , Daniele Durante , David Dunson

Aims: Combinations of treatments can offer additional benefit over the treatments individually. However, trials of these combinations are lower priority than the development of novel therapies, which can restrict funding, timelines and…

Bayesian estimation is increasingly popular for performing model based inference to support policymaking. These data are often collected from surveys under informative sampling designs where subject inclusion probabilities are designed to…

统计方法学 · 统计学 2018-07-13 Luis G. Leon-Novelo , Terrance D. Savitsky