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A mathematical model involving a syntrophic relationship between two populations of bacteria in a continuous culture is proposed. A detailed qualitative analysis is carried out. The local and global stability analysis of the equilibria are…

动力系统 · 数学 2011-08-01 Tewfik Sari , Miled El Hajji , Jérôme Harmand

Cell cultures exhibit rich and complex behaviors driven by dynamic metabolic interactions among cells. In this work, we present a model that captures these interactions through a framework inspired by statistical mechanics. Using Monte…

生物物理 · 物理学 2025-09-25 A. R. Batista-Tomás , C. Díaz-Faloh , R. Mulet

We suggest a novel approach to treating symbiotic relations between biological species or social entities. The main idea is the characterisation of symbiotic relations of coexisting species through their mutual influence on their respective…

种群与进化 · 定量生物学 2015-06-22 V. I. Yukalov , E. P. Yukalova , D. Sornette

We present a model for continuous cell culture coupling intra-cellular metabolism to extracellular variables describing the state of the bioreactor, taking into account the growth capacity of the cell and the impact of toxic byproduct…

分子网络 · 定量生物学 2017-11-21 Jorge Fernandez-de-Cossio-Diaz , Kalet León , Roberto Mulet

We introduce a mathematical model of symbiosis between different species by taking into account the influence of each species on the carrying capacities of the others. The modeled entities can pertain to biological and ecological societies…

生物物理 · 物理学 2012-06-06 V. I. Yukalov , E. P. Yukalova , D. Sornette

Mutualistic interactions, where individuals from different species can benefit from each other, are widespread across ecosystems. This study develops a general deterministic model of mutualism involving two populations, assuming that…

种群与进化 · 定量生物学 2026-02-26 Chloë Mian , Sylvain Billiard , Violaine Llaurens , Charline Smadi

We study analytically and numerically a model metabolic cycle composed of an arbitrary number of species of catalytically active particles. Each species converts a substrate into a product, the latter being used as the substrate by the next…

软凝聚态物质 · 物理学 2023-09-29 Vincent Ouazan-Reboul , Jaime Agudo-Canalejo , Ramin Golestanian

We propose a system of differential equations modeling the competition between two obligate mutualistic species for a single nutrient in a chemostat. Each species promotes the growth of the other, and growth occurs only in the presence of…

动力系统 · 数学 2026-03-12 Tahani Mtar , Radhouane Fekih-Salem

The human gut microbiome is a complex ecosystem, in which hundreds of microbial species and metabolites coexist, in part due to an extensive network of cross-feeding interactions. However, both the large-scale trophic organization of this…

种群与进化 · 定量生物学 2020-07-01 Tong Wang , Akshit Goyal , Veronika Dubinkina , Sergei Maslov

Many of the chemical reactions that take place within a living cell are irreversible. Due to evolutionary pressures, the number of allowable reactions within these systems are highly constrained and thus the resulting metabolic networks…

分子网络 · 定量生物学 2013-03-04 Jonathan J Crofts , Ernesto Estrada

Microbial communities feature an immense diversity of species and this diversity is linked with outcomes ranging from ecosystem stability to medical prognoses. Yet the mechanisms underlying microbial diversity are under debate. While simple…

生物物理 · 物理学 2020-10-20 Amir Erez , Jaime G. Lopez , Benjamin Weiner , Yigal Meir , Ned S. Wingreen

Social interaction between microbes can be described at many levels of details, ranging from the biochemistry of cell-cell interactions to the ecological dynamics of populations. Choosing the best level to model microbial communities…

种群与进化 · 定量生物学 2020-09-09 Chen Liao , Tong Wang , Sergei Maslov , Joao B. Xavier

Previous work has shown that species interacting in an ecosystem and actors transacting in an economic context may have notable similarities in behavior. However, the specific mechanism that may underlie similarities in nature and human…

物理与社会 · 物理学 2011-10-04 Serguei Saavedra , Felix Reed-Tsochas , Brian Uzzi

The exchange of diffusive metabolites is known to control the spatial patterns formed by microbial populations, as revealed by recent studies in the laboratory. However, the matrices used, such as agarose pads, lack the structured geometry…

The gut microbiome plays a crucial role in human health, yet the mechanisms underlying host-microbiome interactions remain unclear, limiting its translational potential. Recent microbiome multiomics studies, particularly paired…

统计方法学 · 统计学 2025-04-09 Haoran Shi , Yue Wang , Dan Cheng

Microbial ecosystems are remarkably diverse, stable, and often consist of a balanced mixture of core and peripheral species. Here we propose a conceptual model exhibiting all these emergent properties in quantitative agreement with real…

种群与进化 · 定量生物学 2018-04-18 Akshit Goyal , Sergei Maslov

A fundamental goal of microbial ecology is to understand what determines the diversity, stability, and structure of microbial ecosystems. The microbial context poses special conceptual challenges because of the strong mutual influences…

生物物理 · 物理学 2019-03-06 Robert Marsland , Wenping Cui , Joshua Goldford , Alvaro Sanchez , Kirill Korolev , Pankaj Mehta

A symmetrical cubic discrete coupled logistic equation is proposed to model the symbiotic interaction of two isolated species. The coupling depends on the population size of both species and on a positive constant $\lambda$, named the…

适应与自组织系统 · 物理学 2007-05-23 Ricardo Lopez-Ruiz , Daniele Fournier-Prunaret

Bacteria possess diverse mechanisms to regulate their motility in response to environmental and physiological signals, enabling them to navigate complex habitats and adapt their behavior. Among these mechanisms, interspecies recognition…

种群与进化 · 定量生物学 2025-12-01 Mattia Mattei , David Soriano Paños , Mahantesh Halappanavar , Alex Arenas

Population dynamics and in particular microbial population dynamics, though they are complex but also intrinsically discrete and random, are conventionally represented as deterministic differential equations systems. We propose to revisit…

种群与进化 · 定量生物学 2014-06-02 Coralie Fritsch , Jérôme Harmand , Fabien Campillo
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