相关论文: Multi-Strain Age-Structured Dengue Transmission Mo…
Urbanization drives the epidemiology of infectious diseases to many threats and new challenges. In this research, we study the interplay between human mobility and dengue outbreaks in the complex urban environment of the city-state of…
In this study, we develop a multi criteria model to identify dengue outbreak periods. To validate the model, we performed a simulation using dengue transmission-related data in Sri Lanka's Western Province. Our results indicated that the…
We consider the problem of controlling the propagation of an epidemic outbreak in an arbitrary contact network by distributing vaccination resources throughout the network. We analyze a networked version of the…
Information regarding vaccines from sources such as health services, media, and social networks can significantly shape vaccination decisions. In particular, the dissemination of negative information can contribute to vaccine hesitancy,…
This work introduces a novel epidemiological model that simultaneously considers multiple viral strains, reinfections due to waning immunity response over time and an optimal control formulation. This enables us to derive optimal mitigation…
In this work we explore the effects of human mobility on the dispersion of a vector borne disease. We combine an already presented stochastic model for dengue with a simple representation of the daily motion of humans on a schematic city of…
Dengue is a notifiable communicable disease in Sri Lanka since 1996. Dengue fever spread rapidly among people living in most of the districts of Sri Lanka. The present notification system of dengue communicable diseases which is enforced by…
Mosquitoes are vectors of viral diseases with epidemic potential in many regions of the world, and in absence of vaccines or therapies, their control is the main alternative. Chemical control through insecticides has been one of the…
Aedes aegypti is a known vector of Dengue, Chikungunya and Zika and the goal of this study is to propose the first mathematical model to describe the dynamic transmission of these three diseases. We present two preliminary models that…
Different extensions of the classical single-strain SIR model for the host population, motivated by modeling dengue fever epidemiology, have reported a rich dynamic structure including deterministic chaos which was able to explain the large…
We introduce a stochastic household model for vector-borne diseases, in particular as relevant to prominent vectors belonging to the Aedes genus and hence the Zika, chikungunya, and dengue viruses. In this model, vectors remain local to…
How to strategically allocate the available vaccines is a crucial issue for pandemic control. In this work, we propose a mathematical framework for optimal stabilizing vaccine allocation, where our goal is to send the infections to zero as…
A central challenge in Human Immunodeficiency Virus (HIV) public health policy lies in determining whether to universally expand treatment access, despite the risk of sub-optimal adherence and consequent drug resistance, or to adopt a more…
The Ebola virus is currently one of the most virulent pathogens for humans. The latest major outbreak occurred in Guinea, Sierra Leonne and Liberia in 2014. With the aim of understanding the spread of infection in the affected countries, it…
Early on during a pandemic, vaccine availability is limited, requiring prioritisation of different population groups. Evaluating vaccine allocation is therefore a crucial element of pandemics response. In the present work, we develop a…
This paper aims to evaluate the potential cost-effectiveness of healthcare interventions against human papillomavirus (HPV). For this, we consider a two-sex epidemic model for the transmission dynamics of HPV which includes screening,…
With approximately half of the world's population at risk of contracting dengue, this mosquito-borne disease is of global concern. International travellers significantly contribute to dengue's rapid and large-scale spread by importing the…
Waning immunity and reinfection are critical features of many infectious diseases, but epidemiological models often fail to capture the intricate interaction between an individual's history of immunity and their current infection status;…
We propose and analyze a new class of controlled multi-type branching processes with a per-step linear resource constraint, motivated by potential applications in viral marketing and cancer treatment. We show that the optimal exponential…
We consider an age-structured epidemic model with two basic public health interventions: (i) identifying and isolating symptomatic cases, and (ii) tracing and quarantine of the contacts of identified infectives. The dynamics of the infected…