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Recently, a variety of vision transformers have been developed as their capability of modeling long-range dependency. In current transformer-based backbones for medical image segmentation, convolutional layers were replaced with pure…

计算机视觉与模式识别 · 计算机科学 2022-08-01 Huimin Huang , Shiao Xie1 , Lanfen Lin , Yutaro Iwamoto , Xianhua Han , Yen-Wei Chen , Ruofeng Tong

It has been shown that genome spatial structures largely affect both genome activity and DNA function. Knowing this, many researchers are currently attempting to accurately model genome structures. Despite these increased efforts there…

基因组学 · 定量生物学 2015-07-24 Jackson Nowotny , Avery Wells , Lingfei Xu , Renzhi Cao , Tuan Trieu , Chenfeng He , Jianlin Cheng

Biologists are leading current research on genome characterization (sequencing, alignment, transcription), providing a huge quantity of raw data about many genome organisms. Extracting knowledge from this raw data is an important process…

定量方法 · 定量生物学 2007-05-23 Nicolas Férey , Pierre-Emmanuel Gros , Joan Hérisson , Rachid Gherbi

Understanding large amounts of spatiotemporal data from particle-based simulations, such as molecular dynamics, often relies on the computation and analysis of aggregate measures. These, however, by virtue of aggregation, hide structural…

计算物理 · 物理学 2019-10-10 Juraj Pálenik , Jan Byška , Stefan Bruckner , Helwig Hauser

We propose a computational method to measure and visualize interrelationships among any number of DNA sequences allowing, for example, the examination of hundreds or thousands of complete mitochondrial genomes. An "image distance" is…

Computation of biological processes creates great promise for everyday life and great challenges for physical scientists. Simulations of molecular dynamics appeal to biologists as a natural extension of structural biology. Once biologists…

生物大分子 · 定量生物学 2019-03-05 Bob Eisenberg

When it is viewed at the scale of a base pair, DNA appears as a nonlinear lattice. Modelling its properties is a fascinating goal. The detailed experiments that can be performed on this system impose constraints on the models and can be…

统计力学 · 物理学 2009-08-26 Michel Peyrard , Santiago Cuesta-Lopez , Guillaume James

Abstract data has no natural scale and so interactive data visualizations must provide techniques to allow the user to choose their viewpoint and scale. Such techniques are well established in desktop visualization tools. The two most…

人机交互 · 计算机科学 2020-11-16 Yalong Yang , Maxime Cordeil , Johanna Beyer , Tim Dwyer , Kim Marriott , Hanspeter Pfister

In industries such as healthcare, finance, and manufacturing, analysis of unstructured textual data presents significant challenges for analysis and decision making. Uncovering patterns within large-scale corpora and understanding their…

计算机视觉与模式识别 · 计算机科学 2025-01-15 Lukas Heine , Fabian Hörst , Jana Fragemann , Gijs Luijten , Jan Egger , Fin Bahnsen , M. Saquib Sarfraz , Jens Kleesiek , Constantin Seibold

The three dimensional structure of DNA in the nucleus (chromatin) plays an important role in many cellular processes. Recent experimental advances have led to high-throughput methods of capturing information about chromatin conformation on…

基因组学 · 定量生物学 2015-11-05 Kevin Emmett , Benjamin Schweinhart , Raul Rabadan

In exploratory tasks involving high-dimensional datasets, dimensionality reduction (DR) techniques help analysts to discover patterns and other useful information. Although scatter plot representations of DR results allow for cluster…

As the rate of data collection continues to grow rapidly, developing visualization tools that scale to immense data sets is a serious and ever-increasing challenge. Existing approaches generally seek to decouple storage and visualization…

数据库 · 计算机科学 2021-06-24 Sam Kumar , Michael P Andersen , David E. Culler

Essential life processes take place across multiple space and time scales in living organisms but understanding their mechanistic interactions remains an ongoing challenge. Advanced multiscale modeling techniques are providing new…

分子网络 · 定量生物学 2025-04-08 Achal Mahajan , Erik J. Navarro , William Poole , Carlos F Lopez

We propose a novel combination of methods that (i) portrays quantitative characteristics of a DNA sequence as an image, (ii) computes distances between these images, and (iii) uses these distances to output a map wherein each sequence is a…

基因组学 · 定量生物学 2013-07-16 Lila Kari , Kathleen A. Hill , Abu Sadat Sayem , Nathaniel Bryans , Katelyn Davis , Nikesh S. Dattani

The human genome is incredibly information-rich, consisting of approximately 25,000 protein-coding genes spread out over 3.2 billion nucleotide base pairs contained within 24 unique chromosomes. The genome is important in maintaining…

人机交互 · 计算机科学 2023-08-28 Gunnar Reiske , Sungwon In , Yalong Yang

We propose a new abstraction set (SynopSet) that has a continuum of visual representations for the explanatory analysis of molecular dynamics simulations (MDS) in the DNA nanotechnology domain. By re-purposing the commonly used progress bar…

定量方法 · 定量生物学 2022-05-04 Deng Luo , Alexandre Kouyoumdjian , Ondřej Strnad , Haichao Miao , Ivan Barišić , Ivan Viola

Large scale visual understanding is challenging, as it requires a model to handle the widely-spread and imbalanced distribution of <subject, relation, object> triples. In real-world scenarios with large numbers of objects and relations,…

计算机视觉与模式识别 · 计算机科学 2019-08-20 Ji Zhang , Yannis Kalantidis , Marcus Rohrbach , Manohar Paluri , Ahmed Elgammal , Mohamed Elhoseiny

Analysis of genomics data is central to nearly all areas of modern biology. Despite significant progress in artificial intelligence (AI) and computational methods, these technologies require significant human oversight to generate novel and…

Several visualization schemes have been developed for imaging materials at the atomic level through atom probe tomography. The main shortcoming of these tools is their inability to parallel process data using multi-core computing units to…

Machine translation between many languages at once is highly challenging, since training with ground truth requires supervision between all language pairs, which is difficult to obtain. Our key insight is that, while languages may vary…

计算与语言 · 计算机科学 2022-04-04 Dídac Surís , Dave Epstein , Carl Vondrick
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