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相关论文: Battling Antibiotic Resistance: Can Machine Learni…

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Antibiotic resistance presents a growing global health crisis, demanding new therapeutic strategies that target novel bacterial mechanisms. Recent advances in protein structure prediction and machine learning-driven molecule generation…

生物大分子 · 定量生物学 2025-05-22 Maximilian G. Schuh , Joshua Hesse , Stephan A. Sieber

Recently, Antimicrobial peptides (AMPs) have been an area of interest in the researches, as the first line of defense against the bacteria. They are raising attention as an efficient way of fighting multidrug resistance. Discovering and…

定量方法 · 定量生物学 2020-05-06 Neda Zarayeneh , Zahra Hanifeloo

Liver infection is a common disease, which poses a great threat to human health, but there is still able to identify an optimal technique that can be used on large-level screening. This paper deals with ML algorithms using different data…

机器学习 · 计算机科学 2023-05-16 P. Deivendran , S. Selvakanmani , S. Jegadeesan , V. Vinoth Kumar

Quantification of heritability is a fundamental desideratum in genetics, which allows an assessment of the contribution of additive genetic variation to the variability of a trait of interest. The traditional computational approaches for…

应用统计 · 统计学 2023-05-03 The Tien Mai , John A Lees , Rebecca A Gladstone , Jukka Corander

Antimicrobial protocols - using substances such as antibiotics or disinfectants - remain the preferred option for preventing the spread of pathogenic bacteria. However, bacteria can develop mechanisms to reduce their antimicrobial…

种群与进化 · 定量生物学 2026-02-17 Nerea Martínez-López , Niclas Nordholt , Frank Schreiber , Míriam R. García

Bacterial infections are responsible for high mortality worldwide. Antimicrobial resistance underlying the infection, and multifaceted patient's clinical status can hamper the correct choice of antibiotic treatment. Randomized clinical…

Diagnostic tests that can detect pre-clinical or sub-clinical infection, are one of the most powerful tools in our armoury of weapons to control infectious diseases. Considerable effort has been paid to improving diagnostic testing for…

While the mechanisms and quantitative details are complex, few analysts would doubt that antibiotic use increases the prevalence of drug-resistant bacterial pathogens among all bacteria causing disease in a population. The causal connection…

种群与进化 · 定量生物学 2018-03-21 Edward Goldstein , Derek R. MacFadden , Marc Lipsitch

The aim of this paper is to study two models for a bacterial population subject to antibiotic treatments. It is known that some bacteria are sensitive to antibiotics. These bacteria are in a state called persistence and each bacterium can…

概率论 · 数学 2013-04-15 Fabio Zucca

Purpose: Antimicrobial resistance is a major global health concern, affecting hospital admissions and treatment success. This study aims to introduce an experimental setup for monitoring bacterial activity over time using image-based…

定量方法 · 定量生物学 2025-06-12 M. A. Gameiro , R. F. Pinto , N. V. Lopes

Understanding how antibiotics inhibit bacteria can help to reduce antibiotic use and hence avoid antimicrobial resistance - yet few theoretical models exist for bacterial growth inhibition by a clinically relevant antibiotic treatment…

细胞行为 · 定量生物学 2017-12-06 Philip Greulich , Jakub Dolezal , Matthew Scott , Martin R. Evans , Rosalind J. Allen

Antimicrobial resistance (AMR) is a growing global crisis projected to cause 10 million deaths per year by 2050. While the WHO Global Antimicrobial Resistance and Use Surveillance System (GLASS) provides standardized surveillance data…

机器学习 · 计算机科学 2026-02-27 Md Tanvir Hasan Turja

The worldwide increase of antimicrobial resistance (AMR) is a serious threat to human health. To avert the spread of AMR, fast reliable diagnostics tools that facilitate optimal antibiotic stewardship are an unmet need. In this regard,…

Antimicrobial resistance (AMR) is a growing public health threat, estimated to cause over 10 million deaths per year and cost the global economy 100 trillion USD by 2050 under status quo projections. These losses would mainly result from an…

Tuberculosis (TB) remains a global health threat, ranking among the leading causes of mortality worldwide. In this context, machine learning (ML) has emerged as a transformative force, providing innovative solutions to the complexities…

The rise of Antimicrobial Resistance, particularly Multi-Drug Resistance (MDR), presents a critical challenge for clinical decision-making due to limited treatment options and delays in conventional susceptibility testing. This study…

机器学习 · 计算机科学 2026-03-03 Santanam Wishal , Riad Sahara

Artificial Intelligence (AI) and infectious diseases prediction have recently experienced a common development and advancement. Machine learning (ML) apparition, along with deep learning (DL) emergence, extended many approaches against…

机器学习 · 计算机科学 2025-01-29 Selestine Melchane , Youssef Elmir , Farid Kacimi , Larbi Boubchir

Rapid identification of bacteria is essential to prevent the spread of infectious disease, help combat antimicrobial resistance, and improve patient outcomes. Raman optical spectroscopy promises to combine bacterial detection,…

Antimicrobial resistance is an important public health concern that has implications in the practice of medicine worldwide. Accurately predicting resistance phenotypes from genome sequences shows great promise in promoting better use of…

Antimicrobial resistance is a silent pandemic that is being exacerbated by the uncontrolled use of antibiotics. Since the discovery of penicillin, we have been largely dependent on microbe-derived small molecules to treat bacterial…

种群与进化 · 定量生物学 2022-10-26 Hyunjin Shim