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We extend replica exchange simulation in two ways, and apply our approaches to biomolecules. The first generalization permits exchange simulation between models of differing resolution -- i.e., between detailed and coarse-grained models.…

生物大分子 · 定量生物学 2009-11-11 Edward Lyman , F. Marty Ytreberg , Daniel M. Zuckerman

Early detection of chronic kidney disease (CKD) is essential for preventing progression to end-stage renal disease. However, existing screening tools - primarily developed using populations from high-income countries - often underperform in…

This study analyses the current viability of this business based on a sample of European countries in the year 2019; countries where electricity prices (day-ahead market) and financial conditions show a certain degree of heterogeneity. We…

综合经济学 · 经济学 2023-09-26 Fernando Núñez , David Canca , Ángel Arcos-Vargas

Patients associated with multiple co-occurring health conditions often face aggravated complications and less favorable outcomes. Co-occurring conditions are especially prevalent among individuals suffering from kidney disease, an…

机器学习 · 计算机科学 2021-09-21 Moumita Bhattacharya , Claudine Jurkovitz , Hagit Shatkay

The cause-specific cumulative incidence function (CIF) quantifies the subject-specific disease risk with competing risk outcome. With longitudinally collected biomarker data, it is of interest to dynamically update the predicted CIF by…

定量方法 · 定量生物学 2019-06-14 Cai Wu , Liang Li , Ruosha Li

Partial nephrectomy (PN) is common surgery in urology. Digitization of renal anatomies brings much help to many computer-aided diagnosis (CAD) techniques during PN. However, the manual delineation of kidney vascular system and tumor on each…

图像与视频处理 · 电气工程与系统科学 2023-05-24 Nan Ma , Ying Yang , Dongkai Zhou

Histopathology foundation models (HFMs), pretrained on large-scale cancer datasets, have advanced computational pathology. However, their applicability to non-cancerous chronic kidney disease remains underexplored, despite coexistence of…

Ultrasound, because of its low cost, non-ionizing, and non-invasive characteristics, has established itself as a cornerstone radiological examination. Research on ultrasound applications has also expanded, especially with image analysis…

图像与视频处理 · 电气工程与系统科学 2022-12-06 Rohit Singla , Cailin Ringstrom , Grace Hu , Victoria Lessoway , Janice Reid , Christopher Nguan , Robert Rohling

Purpose: To improve kidney segmentation in clinical ultrasound (US) images, we develop a new graph cuts based method to segment kidney US images by integrating original image intensity information and texture feature maps extracted using…

计算机视觉与模式识别 · 计算机科学 2017-06-13 Qiang Zheng , Steven Warner , Gregory Tasian , Yong Fan

The ongoing transformation of the European energy landscape, driven by the integration of renewable energy sources, digital technologies, and decentralized systems, requires a high degree of interoperability across diverse components and…

软件工程 · 计算机科学 2026-02-11 Thomas I. Strasser , Edmund Widl , Carlos Ayon Mac Gregor , Mirko Ginocchi , Rene Kuchenbuch

Efficiently quantifying renal structures can provide distinct spatial context and facilitate biomarker discovery for kidney morphology. However, the development and evaluation of the transformer model to segment the renal cortex, medulla,…

图像与视频处理 · 电气工程与系统科学 2022-03-07 Xin Yu , Yucheng Tang , Yinchi Zhou , Riqiang Gao , Qi Yang , Ho Hin Lee , Thomas Li , Shunxing Bao , Yuankai Huo , Zhoubing Xu , Thomas A. Lasko , Richard G. Abramson , Bennett A. Landman

A status report about the International Lattice Data Grid (ILDG) is given. Different countries participating in the ILDG have created regional lattice data grid solutions that are implemented, working and used. The remaining task and the…

高能物理 - 格点 · 物理学 2011-07-19 Karl Jansen

Considering the sequential clearing of energy and reserves in Europe, enabling inter-area reserve exchange requires optimally allocating inter-area transmission capacities between these two markets. To achieve this, we provide a…

最优化与控制 · 数学 2021-07-14 Orcun Karaca , Stefanos Delikaraoglou , Maryam Kamgarpour

Chronic kidney disease (CKD) affects millions worldwide and progresses irreversibly through stages culminating in end-stage renal disease (ESRD) and death. Outcome trials in CKD traditionally employ time-to-first-event analyses using the…

统计方法学 · 统计学 2026-01-27 Jiren Sun , Tuo Wang , Yu Du

The in-vivo identification of the kidney stone types during an ureteroscopy would be a major medical advance in urology, as it could reduce the time of the tedious renal calculi extraction process, while diminishing infection risks.…

Objective: To improve prediction of Chronic Kidney Disease (CKD) progression to End Stage Renal Disease (ESRD) using machine learning (ML) and deep learning (DL) models applied to an integrated clinical and claims dataset of varying…

定量方法 · 定量生物学 2025-05-06 Yubo Li , Rema Padman

In this paper an econophysics model for the currency exchange operations with commission is proposed. With this purpose some analogies and similarities of the processes that take place in the frame of the electrochemical system made from…

投资组合管理 · 定量金融 2010-05-04 Ion Spanulescu , Victor A. Stoica , Ion Popescu

We study a setting where a set of agents engage in pairwise exchanges of freely replicable goods (e.g., digital goods such as data), where two agents grant each other a copy of a good they possess in exchange for a good they lack. Such…

计算机科学与博弈论 · 计算机科学 2026-03-16 Shangyuan Yang , Kirthevasan Kandasamy

Five year post-transplant survival rate is an important indicator on quality of care delivered by kidney transplant centers in the United States. To provide a fair assessment of each transplant center, an effect that represents the…

应用统计 · 统计学 2017-03-13 Lanfeng Pan , Yehua Li , Kevin He , Yanming Li , Yi Li

Aligning protein interaction networks (PPI) of two or more organisms consists of finding a mapping of the nodes (proteins) of the networks that captures important structural and functional associations (similarity). It is a well studied but…

分子网络 · 定量生物学 2020-10-12 Concettina Guerra , Pietro Hiram Guzzi