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The principles of neural encoding and computations are inherently collective and usually involve large populations of interacting neurons with highly correlated activities. While theories of neural function have long recognized the…

神经元与认知 · 定量生物学 2019-05-14 Christophe Gardella , Olivier Marre , Thierry Mora

As experiments advance to record from tens of thousands of neurons, statistical physics provides a framework for understanding how collective activity emerges from networks of fine-scale correlations. While modeling these populations is…

生物物理 · 物理学 2024-12-25 David P. Carcamo , Christopher W. Lynn

The efficient coding theory postulates that single cells in a neuronal population should be optimally configured to efficiently encode information about a stimulus subject to biophysical constraints. This poses the question of how multiple…

神经元与认知 · 定量生物学 2023-08-11 Shuai Shao , Markus Meister , Julijana Gjorgjieva

Decoding stimuli or behaviour from recorded neural activity is a common approach to interrogate brain function in research, and an essential part of brain-computer and brain-machine interfaces. Reliable decoding even from small neural…

神经元与认知 · 定量生物学 2023-01-06 Justin Jude , Matthew G. Perich , Lee E. Miller , Matthias H. Hennig

The inverse Ising model is used in computational neuroscience to infer probability distributions of the synchronous activity of large neuronal populations. This method allows for finding the Boltzmann distribution with single neuron biases…

神经元与认知 · 定量生物学 2022-07-27 Geoffroy Delamare , Ulisse Ferrari

A main concern in cognitive neuroscience is to decode the overt neural spike train observations and infer latent representations under neural circuits. However, traditional methods entail strong prior on network structure and hardly meet…

神经元与认知 · 定量生物学 2019-11-22 Zhijie Chen , Junchi Yan , Longyuan Li , Xiaokang Yang

Over the brief time intervals available for processing retinal output, roughly 50 to 300 msec, the number of extra spikes generated by individual ganglion cells can be quite variable. Here, computer-generated spike trains were used to…

神经元与认知 · 定量生物学 2007-09-14 Garrett T. Kenyon

Simultaneously recorded neurons exhibit correlations whose underlying causes are not known. Here, we use a population of threshold neurons receiving correlated inputs to model neural population recordings. We show analytically that small…

神经元与认知 · 定量生物学 2010-09-20 Jakob H Macke , Manfred Opper , Matthias Bethge

Our ability to use deep learning approaches to decipher neural activity would likely benefit from greater scale, in terms of both model size and datasets. However, the integration of many neural recordings into one unified model is…

Neural populations encode information about their stimulus in a collective fashion, by joint activity patterns of spiking and silence. A full account of this mapping from stimulus to neural activity is given by the conditional probability…

神经元与认知 · 定量生物学 2013-06-14 Einat Granot-Atedgi , Gašper Tkačik , Ronen Segev , Elad Schneidman

Recording simultaneous activity of hundreds of neurons is now possible. Existing methods can model such population activity, but do not directly reveal the computations used by the brain. We present a fully unsupervised method that models…

神经元与认知 · 定量生物学 2020-03-24 Connor Brennan , Alex Proekt

We tackle a quantification of synchrony in a large ensemble of interacting neurons from the observation of spiking events. In a simulation study, we efficiently infer the synchrony level in a neuronal population from a point process…

神经元与认知 · 定量生物学 2025-03-25 Arkady Pikovsky , Michael Rosenblum

The availability of large-scale neuronal population datasets necessitates new methods to model population dynamics and extract interpretable, scientifically translatable insights. Existing deep learning methods often overlook the biological…

神经元与认知 · 定量生物学 2024-11-14 Parsa Delavari , Ipek Oruc , Timothy H Murphy

The characterization of coordinated activity in neuronal populations has received renewed interest in the light of advancing experimental techniques which allow recordings from multiple units simultaneously. Across both in vitro and in vivo…

神经元与认知 · 定量生物学 2015-06-16 Feraz Azhar , William S. Anderson

Neural correlations play a critical role in sensory information coding. They are of two kinds: signal correlations, when neurons have overlapping sensitivities, and noise correlations from network effects and shared noise. In experiments…

神经元与认知 · 定量生物学 2025-07-03 Gabriel Mahuas , Thomas Buffet , Olivier Marre , Ulisse Ferrari , Thierry Mora

Generalized linear models are one of the most efficient paradigms for predicting the correlated stochastic activity of neuronal networks in response to external stimuli, with applications in many brain areas. However, when dealing with…

无序系统与神经网络 · 物理学 2020-11-17 Gabriel Mahuas , Giulio Isacchini , Olivier Marre , Ulisse Ferrari , Thierry Mora

Recent advances in experimental techniques enable the simultaneous recording of activity from thousands of neurons in the brain, presenting both an opportunity and a challenge: to build meaningful, scalable models of large neural…

生物物理 · 物理学 2025-08-05 Luca Di Carlo , Francesca Mignacco , Christopher W. Lynn , William Bialek

Neural coding is a key problem in neuroscience, which can promote people's understanding of the mechanism that brain processes information. Among the classical theories of neural coding, the population rate coding has been studied widely in…

神经元与认知 · 定量生物学 2019-08-13 Hao Si , Xiaojuan Sun

Recent advances in experimental techniques have allowed the simultaneous recording of populations of hundreds of neurons, allowing more comprehensive investigation into the nature of the collective structure of population neural activity.…

神经元与认知 · 定量生物学 2018-02-07 Mark L. Ioffe , Michael J. Berry

Perceptions and actions, thoughts and memories result from coordinated activity in hundreds or even thousands of neurons in the brain. It is an old dream of the physics community to provide a statistical mechanics description for these and…

无序系统与神经网络 · 物理学 2024-09-04 Leenoy Meshulam , William Bialek
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