相关论文: Modeling Drug-Disease Relations with Linguistic an…

High-quality data is a key aspect of modern machine learning. However, labels generated by humans suffer from issues like label noise and class ambiguities. We raise the question of whether hard labels are sufficient to represent the…

Identification of disease genes, which are a set of genes associated with a disease, plays an important role in understanding and curing diseases. In this paper, we present a biomedical knowledge graph designed specifically for this…

In this work, we aim at equipping pre-trained language models with structured knowledge. We present two self-supervised tasks learning over raw text with the guidance from knowledge graphs. Building upon entity-level masked language models,…

Crucial information about the practice of healthcare is recorded only in free-form text, which creates an enormous opportunity for high-impact NLP. However, annotated healthcare datasets tend to be small and expensive to obtain, which…

Personalized drug response has received public awareness in recent years. How to combine gene test result and drug sensitivity records is regarded as essential in the real-world implementation. Research articles are good sources to train…

We introduce an expert curated, real-world benchmark for evaluating document-grounded question-answering (QA) motivated by generic drug assessment, using the U.S. Food and Drug Administration (FDA) drug label documents. Drug labels contain…

Large language models (LLMs) have shown promise in table Question Answering (Table QA). However, extending these capabilities to multi-table QA remains challenging due to unreliable schema linking across complex tables. Existing methods…

Large Language Models (LLMs) have shown remarkable capabilities across various domains, yet they struggle with knowledge-intensive tasks in areas that demand factual accuracy, e.g. industrial automation and healthcare. Key limitations…

Social media is one of the most highly sought resources for analyzing characteristics of the language by its users. In particular, many researchers utilized various linguistic features of mental health problems from social media. However,…

For Artificial Intelligence to have a greater impact in biology and medicine, it is crucial that recommendations are both accurate and transparent. In other domains, a neurosymbolic approach of multi-hop reasoning on knowledge graphs has…

In many supervised learning tasks, the entities to be labeled are related to each other in complex ways and their labels are not independent. For example, in hypertext classification, the labels of linked pages are highly correlated. A…

Relation extraction represents a fundamental component in the process of creating knowledge graphs, among other applications. Large language models (LLMs) have been adopted as a promising tool for relation extraction, both in supervised and…

Inferring causal relationships between variable pairs is crucial for understanding multivariate interactions in complex systems. Knowledge-based causal discovery -- which involves inferring causal relationships by reasoning over the…

Drug-drug interaction (DDI) prediction is critical for treatment safety. While large language models (LLMs) show promise in pharmaceutical tasks, their effectiveness in DDI prediction remains challenging. Inspired by the well-established…

Keyword-based searches are today's standard in digital libraries. Yet, complex retrieval scenarios like in scientific knowledge bases, need more sophisticated access paths. Although each document somewhat contributes to a domain's body of…

Increasing amounts of freely available data both in textual and relational form offers exploration of richer document representations, potentially improving the model performance and robustness. An emerging problem in the modern era is fake…

Instead of using expensive manual annotations, researchers have proposed to train named entity recognition (NER) systems using heuristic labeling rules. However, devising labeling rules is challenging because it often requires a…

The contributions of model complexity, data volume, and feature modalities to knowledge graph-based drug repurposing remain poorly quantified under rigorous temporal validation. We constructed a pharmacology knowledge graph from ChEMBL 36…

The Web is a potentially huge source of medical drug leads. But despite the significant amount of multi- dimensional information about drugs, currently commercial search engines accept only linear keyword strings as inputs. This work uses…

Traditional relational databases contain a lot of latent semantic information that have largely remained untapped due to the difficulty involved in automatically extracting such information. Recent works have proposed unsupervised machine…