中文
相关论文

相关论文: Modeling Drug-Disease Relations with Linguistic an…

200 篇论文

In document classification, graph-based models effectively capture document structure, overcoming sequence length limitations and enhancing contextual understanding. However, most existing graph document representations rely on heuristics,…

计算与语言 · 计算机科学 2025-08-05 Margarita Bugueño , Gerard de Melo

Drug-drug interaction prediction is a crucial issue in molecular biology. Traditional methods of observing drug-drug interactions through medical experiments require significant resources and labor. This paper presents a medical knowledge…

计算与语言 · 计算机科学 2024-07-29 Peng Gao , Feng Gao , Jian-Cheng Ni , Yu Wang , Fei Wang

Originally designed to model text, topic modeling has become a powerful tool for uncovering latent structure in domains including medicine, finance, and vision. The goals for the model vary depending on the application: in some cases, the…

机器学习 · 统计学 2014-11-24 Finale Doshi-Velez , Byron Wallace , Ryan Adams

Medical professionals frequently work in a data constrained setting to provide insights across a unique demographic. A few medical observations, for instance, informs the diagnosis and treatment of a patient. This suggests a unique setting…

计算与语言 · 计算机科学 2022-12-06 Pankaj Sharma , Imran Qureshi , Minh Tran

Off-the-shelf biomedical embeddings obtained from the recently released various pre-trained language models (such as BERT, XLNET) have demonstrated state-of-the-art results (in terms of accuracy) for the various natural language…

计算与语言 · 计算机科学 2020-12-22 Ishani Mondal

Relation extraction between drugs plays a crucial role in identifying drug drug interactions and predicting side effects. The advancement of machine learning methods in relation extraction, along with the development of large medical text…

计算与语言 · 计算机科学 2025-10-28 Ali Fata , Hossein Rahmani , Parinaz Soltanzadeh , Amirhossein Derakhshan , Behrouz Minaei Bidgoli

Machine learning-based multi-label medical text classifications can be used to enhance the understanding of the human body and aid the need for patient care. We present a broad study on clinical natural language processing techniques to…

信息检索 · 计算机科学 2020-04-02 Vithya Yogarajan , Jacob Montiel , Tony Smith , Bernhard Pfahringer

Recent research on predicting the binding affinity between drug molecules and proteins use representations learned, through unsupervised learning techniques, from large databases of molecule SMILES and protein sequences. While these…

This paper proposes a graph-augmented reasoning framework for tobacco pest and disease management that integrates structured domain knowledge into large language models. Building on GraphRAG, we construct a domain-specific knowledge graph…

计算与语言 · 计算机科学 2026-02-04 Siyu Li , Chenwei Song , Qi Zhou , Wan Zhou , Xinyi Liu

Owing to the exponential rise in the electronic medical records, information extraction in this domain is becoming an important area of research in recent years. Relation extraction between the medical concepts such as medical problem,…

计算与语言 · 计算机科学 2019-03-26 Dhanachandra Ningthoujam , Shweta Yadav , Pushpak Bhattacharyya , Asif Ekbal

Drug discovery is a critical task in biomedical natural language processing (NLP), yet explainable drug discovery remains underexplored. Meanwhile, large language models (LLMs) have shown remarkable abilities in natural language…

计算与语言 · 计算机科学 2025-02-28 Kai Zhang , Rui Zhu , Shutian Ma , Jingwei Xiong , Yejin Kim , Fabricio Murai , Xiaozhong Liu

Drug repurposing is more relevant than ever due to drug development's rising costs and the need to respond to emerging diseases quickly. Knowledge graph embedding enables drug repurposing using heterogeneous data sources combined with…

Knowledge base construction is crucial for summarising, understanding and inferring relationships between biomedical entities. However, for many practical applications such as drug discovery, the scarcity of relevant facts (e.g. gene X is…

计算与语言 · 计算机科学 2019-07-04 Julien Fauqueur , Ashok Thillaisundaram , Theodosia Togia

The graph structure of biomedical data differs from those in typical knowledge graph benchmark tasks. A particular property of biomedical data is the presence of long-range dependencies, which can be captured by patterns described as…

机器学习 · 计算机科学 2020-07-13 Yushan Liu , Marcel Hildebrandt , Mitchell Joblin , Martin Ringsquandl , Volker Tresp

OBJECTIVE: Leverage existing biomedical NLP tools and DS domain terminology to produce a novel and comprehensive knowledge graph containing dietary supplement (DS) information for discovering interactions between DS and drugs, or…

In this paper, we introduce the problem of knowledge graph contextualization -- that is, given a specific NLP task, the problem of extracting meaningful and relevant sub-graphs from a given knowledge graph. The task in the case of this…

人工智能 · 计算机科学 2020-02-05 Kshitij Fadnis , Kartik Talamadupula , Pavan Kapanipathi , Haque Ishfaq , Salim Roukos , Achille Fokoue

Knowledge graphs can represent information about the real-world using entities and their relations in a structured and semantically rich manner and they enable a variety of downstream applications such as question-answering, recommendation…

计算与语言 · 计算机科学 2023-05-16 Hanieh Khorashadizadeh , Nandana Mihindukulasooriya , Sanju Tiwari , Jinghua Groppe , Sven Groppe

One of the most difficult aspects of modeling complex dilemmas in decision-analytic terms is composing a diagram of relevance relations from a set of domain concepts. Decision models in domains such as medicine, however, exhibit certain…

人工智能 · 计算机科学 2013-03-08 John W. Egar , Mark A. Musen

We introduce Bi-GNN for modeling biological link prediction tasks such as drug-drug interaction (DDI) and protein-protein interaction (PPI). Taking drug-drug interaction as an example, existing methods using machine learning either only…

计算工程、金融与科学 · 计算机科学 2020-06-26 Yunsheng Bai , Ken Gu , Yizhou Sun , Wei Wang

Large language models (LLMs) are increasingly used in the mental health domain, yet it remains unclear how well they capture related biomedical knowledge and how reliably they apply it to clinically salient structured judgments. Here, we…