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Proliferation is a defining feature of life. Through growth, division, and death, living systems consume energy and inject mass, breaking conservation laws and driving collective phenomena from biofilm formation to embryonic development.…

统计力学 · 物理学 2026-03-25 Nicola Pellicciotta , Luca Angelani , Roberto Di Leonardo

Growth in bacterial populations generally depends on the environment (availability and quality of nutrients, presence of a toxic inhibitor, product inhibition..). Here, we build a model to describe the action of a bacteriostatic antibiotic,…

生物物理 · 物理学 2025-06-25 Barnabe Ledoux , David Lacoste

We investigate the dynamics of a colony of crawling, proliferating cells with a minimal, mechanical cell model. The cells consist of two disks, modelling the cell body and a pseudopod, connected by a finite extensible spring. The cells…

细胞行为 · 定量生物学 2019-04-11 Simon K. Schnyder , John J. Molina , Ryoichi Yamamoto

Mechanical stresses stemming from environmental factors are a key determinant of cellular behavior and physiology. Yet, the role of self-induced biomechanical stresses in growing bacterial colonies has remained largely unexplored. Here, we…

We investigate the traveling front solutions of a nonlocal Lotka Volterra system to illustrate the outcome of the competition between two species. The existence of the front solution is obtained through a new monotone iteration scheme, the…

动力系统 · 数学 2013-06-24 Xiaojie hou , Biao Wang , Zhence Zhang

This paper is concerned with reaction-diffusion systems of two symmetric species in spatial dimension one, having two stable symmetric equilibria connected by a symmetric standing front. The first order variation of the speed of this front…

偏微分方程分析 · 数学 2017-03-08 Emmanuel Risler

In addressing the origins of Darwinian evolution, recent experimental work has been focussed on the discovery of simple physical effects which would provide a relevant selective advantage to protocells competing with each other for a…

定量方法 · 定量生物学 2014-07-15 Ben Shirt-Ediss , Kepa Ruiz-Mirazo , Fabio Mavelli , Ricard V. Solé

How motile bacteria move near a surface is a problem of fundamental biophysical interest and is key to the emergence of several phenomena of biological, ecological and medical relevance, including biofilm formation. Solid boundaries can…

生物物理 · 物理学 2019-09-12 Stanislaw Makarchuk , Vasco C. Braz , Nuno A. M. Araújo , Lena Ciric , Giorgio Volpe

We introduce a model called Host-Pathogen game for studying biological competitions. Notably, we focus on the invasive dynamics of external agents, like bacteria, within a host organism. The former are mapped to a population of defectors…

种群与进化 · 定量生物学 2018-09-03 Marco Alberto Javarone

Using game theory we provide mathematical proof that if a species of asexually reproducing microbes does not possess maximum variability in competitive abilities amongst its individual organisms, then that species is vulnerable to…

种群与进化 · 定量生物学 2020-12-15 Susanne Menden-Deuer , Julie Rowlett

Bacteria frequently colonize natural microcavities such as gut crypts, plant apoplasts, and soil pores. Recent studies have shown that the physical structure of these spaces plays a crucial role in shaping the stability and resilience of…

种群与进化 · 定量生物学 2025-03-28 Valentin Slepukhin , Víctor Peris Yagüe , Christian Westendorf , Birgit Koch , Oskar Hallatschek

Certain invasive plants may rely on interference mechanisms (allelopathy, e.g.) to gain competitive superiority over native species. But expending resources on interference presumably exacts a cost in another life-history trait, so that the…

种群与进化 · 定量生物学 2012-06-08 Andrew Allstadt , Thomas Caraco , F. Molnar , G. Korniss

We introduce and analyze a spatial Lotka-Volterra competition model with local and nonlocal interactions. We study two alternative classes of nonlocal competition that differ in how each species' characteristics determine the range of the…

种群与进化 · 定量生物学 2021-07-14 Gabriel Andreguetto Maciel , Ricardo Martinez-Garcia

The global dynamics of the two-species Lotka-Volterra competition patch model with asymmetric dispersal is classified under the assumptions of weak competition and the weighted digraph of the connection matrix is strongly connected and…

经典分析与常微分方程 · 数学 2022-01-19 Shanshan Chen , Junping Shi , Zhisheng Shuai , Yixiang Wu

Motile bacteria can migrate along chemical gradients in a process known as chemotaxis. When exposed to uniform environmental stress, Escherichia coli cells coordinate their chemotactic responses to form millimeter-sized condensates…

生物物理 · 物理学 2025-05-02 Nir Livne , Ady Vaknin , Oded Agam

Cooperation is vital for the survival of a swarm$^1$. Large scale cooperation allows murmuring starlings to outmaneuver preying falcons$^2$, shoaling sardines to outsmart sea lions$^3$, and homo sapiens to outlive their Pleistocene…

软凝聚态物质 · 物理学 2021-01-01 Matan Yah Ben Zion , Alvin Modin , Yaelin Caba , Paul M Chaikin

This paper studies the spreading dynamics of a high-dimensional strong competition Lotka-Volterra system where two species initially occupy disjoint measurable (possibly unbounded) subsets in $\mathbb{R}^N$, which are called initial…

偏微分方程分析 · 数学 2026-02-26 Hongjun Guo

Bacteria build multicellular communities termed biofilms, which are often encased in a self-secreted extracellular matrix that gives the community mechanical strength and protection against harsh chemicals. How bacteria assemble distinct…

生物物理 · 物理学 2023-09-27 Jakub A. Kochanowski , Bobby Carroll , Merrill E. Asp , Emma Kaputa , Alison E. Patteson

Adding a non-adsorbing polymer to passive colloids induces an attraction between the particles via the `depletion' mechanism. High enough polymer concentrations lead to phase separation. We combine experiments, theory and simulations to…

软凝聚态物质 · 物理学 2016-07-13 J. Schwarz-Linek , C. Valeriani , A. Cacciuto , M. E. Cates , D. Marenduzzo , A. N. Morozov , W. C. K. Poon

We study the spreading of a bacterial colony undergoing turbulent like collective motion. We present two minimalistic models to investigate the interplay between population growth and coherent structures arising from turbulence. Using…

流体动力学 · 物理学 2017-04-06 Rayan Chatterjee , Abhijeet A. Joshi , Prasad Perlekar