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Accurate reconstruction of ambient temperature at death scenes is crucial for estimating the postmortem interval (PMI) in forensic science. Typically, this is done by correcting weather station temperatures using measurements from the…

应用统计 · 统计学 2024-09-17 Jędrzej Wydra , Łukasz Smaga , Szymon Matuszewski

Quantitative Magnetic Resonance Imaging (qMRI) provides researchers insight into pathological and physiological alterations of living tissue, with the help of which researchers hope to predict (local) therapeutic efficacy early and…

应用统计 · 统计学 2008-07-30 Xiaoxi Zhang , Timothy D. Johnson , Roderick J. A. Little , Yue Cao

Industry standards require medical device manufacturers to perform implant-induced artefact testing in phantoms at a pre-clinical stage to define the extent of artefacts that can be expected during MRI. Once a device is commercially…

医学物理 · 物理学 2023-06-19 Guy Fierens , Joris Walraevens , Ronald Peeters , Christ Glorieux , Nicolas Verhaert

Paralytic Ileus (PI) patients are at high risk of death when admitted to the Intensive care unit (ICU), with mortality as high as 40\%. There is minimal research concerning PI patient mortality prediction. There is a need for more accurate…

机器学习 · 计算机科学 2021-08-04 Maryam Pishgar , Martha Razo , Julian Theis , Houshang Darabi

Traditional approaches for molecular imaging of Parkinson's disease (PD) in vivo require radioactive isotopes, lengthy scan times, or deliver only low spatial resolution. Recent advances in saturation transfer-based PD magnetic resonance…

医学物理 · 物理学 2025-12-24 Hagar Shmuely , Michal Rivlin , Or Perlman

Quantitative phase imaging (QPI) quantifies the sample-specific optical-phase-delay enabling objective studies of optically-transparent specimens such as biological samples, but lacks chemical sensitivity limiting its application to…

光学 · 物理学 2019-09-04 Miu Tamamitsu , Keiichiro Toda , Ryoichi Horisaki , Takuro Ideguchi

Quantitative magnetic resonance imaging (qMRI) allows images to be compared across sites and time points, which is particularly important for assessing long-term conditions or for longitudinal studies. The multiparametric mapping (MPM)…

信号处理 · 电气工程与系统科学 2024-10-24 Klara Baś , Christian Lambert , John Ashburner

Pharmacological challenge imaging has mapped, but rarely quantified, the sensitivity of a biological system to a given drug. We describe a novel method called rapid quantitative pharmacodynamic imaging. This method combines…

定量方法 · 定量生物学 2014-05-28 Kevin J. Black , Jonathan M. Koller , Brad D. Miller

Vital signs and laboratory values are routinely used to guide clinical decision-making for polytrauma patients, such as the decision to use damage control techniques versus early definitive fracture fixation. Prior multivariate models have…

Modern MRI relies on the well-established Echo-Planar-Imaging (EPI) method for fast acquisition. EPI is the workhorse of diffusion and functional MRI in neuroscience as well as of many dynamic applications for clinical body imaging. Its…

Positron emission tomography (PET) is an important modality for diagnosing diseases such as cancer and Alzheimer's disease, capable of revealing the uptake of radiolabeled molecules that target specific pathological markers of the diseases.…

医学物理 · 物理学 2025-01-17 Hsin-Hsiung Huang , Zheyuan Zhu , Slun Booppasiri , Zhuo Chen , Shuo Pang , Chien-Min Kao

Functional magnetic resonance spectroscopy (fMRS) quantifies metabolic variations upon presentation of a stimulus and can therefore provide complementary information compared to functional magnetic resonance imaging (fMRI). However, to our…

医学物理 · 物理学 2020-01-24 Clémence Ligneul , Francisca F. Fernandes , Noam Shemesh

Quantum methods are increasingly proposed for healthcare, but translational biomarker studies demand transparent benchmarking and robust small-dataset evaluation. We analysed a preclinical COPD cohort of 213 animals with blood and…

机器学习 · 计算机科学 2026-04-21 Azadeh Alavi , Hamidreza Khalili , Stanley H. Chan , Fatemeh Kouchmeshki , Muhammad Usman , Ross Vlahos

We propose a novel a-posteriori error estimation technique where the target quantities of interest are ratios of high-dimensional integrals, as occur e.g. in PDE constrained Bayesian inversion and PDE constrained optimal control subject to…

数值分析 · 数学 2023-07-07 Marcello Longo , Christoph Schwab , Andreas Stein

This work examines the hypothesis that intravoxel incoherent motion MRI (IVIM) can quantify local cerebral blood flow (qCBF), infarct volume, and define the ischemic penumbra for determination of the perfusion-diffusion mismatch (PWI/DWI)…

Quantitative analysis of fetal lung Diffusion-Weighted MRI (DWI) data shows potential in providing quantitative imaging biomarkers that indirectly reflect fetal lung maturation. However, fetal motion during the acquisition hampered…

计算机视觉与模式识别 · 计算机科学 2022-08-23 Yael Zaffrani-Reznikov , Onur Afacan , Sila Kurugol , Simon Warfield , Moti Freiman

Accurate preoperative prediction of erectile dysfunction (ED) is important for counseling patients undergoing radical prostatectomy. While clinical features are established predictors, the added value of preoperative MRI remains…

Capturing dynamic spatiotemporal neural activity is essential for understanding large-scale brain mechanisms. Functional magnetic resonance imaging (fMRI) provides high-resolution cortical representations that form a strong basis for…

图像与视频处理 · 电气工程与系统科学 2026-04-01 Wanying Qu , Jianxiong Gao , Wei Wang , Yanwei Fu

Purpose: To develop an accelerated Cartesian MRF implementation using a multi-shot EPI sequence for rapid simultaneous quantification of T1 and T2 parameters. Methods: The proposed Cartesian MRF method involved the acquisition of highly…

The study reports the performance of Parkinson's disease (PD) patients to operate Motor-Imagery based Brain-Computer Interface (MI-BCI) and compares three selected pre-processing and classification approaches. The experiment was conducted…

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