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Purpose: Recent work highlights the breadth of reported spin-lattice relaxation rates ($R_1$) for individual tissues. One potential source of variation is the protocol used to determine $R_1$. The methodological dependence of R1 and…
Fundamental knowledge in activity recognition of individuals with motor disorders such as Parkinson's disease (PD) has been primarily limited to detection of steady-state/static tasks (sitting, standing, walking). To date, identification of…
Motor cortex (M1) is a crucial brain area for controlling voluntary movements, such as reaching and grasping for a cup of coffee. M1 is organized in a somatotopic manner, such that M1 output driving movement to different parts of the body…
Background: Cognitive impairment in multiple sclerosis (MS) is driven by both focal inflammation and compartmentalized neurodegeneration, yet the relative effect of lesion-independent thalamic atrophy on information processing speed (IPS)…
To minimize functional morbidity associated with brain surgery, new preventive approaches (also referred to as "prehabilitation") by using motor-imagery-based computer interfaces (MI-BCIs) can be utilized. To achieve successful MI-BCI…
This study aims at the effects of traumatic brachial plexus lesion with root avulsions (BPA) upon the organization of the primary motor cortex (M1). Nine right-handed patients with a right BPA in whom an intercostal to musculocutaneous…
The loss of limb motion arising from damage to the spinal cord is a disability that could effect people while performing their day-to-day activities. The restoration of limb movement would enable people with spinal cord injury to interact…
Functional brain connectivity, as revealed through distant correlations in the signals measured by functional Magnetic Resonance Imaging (fMRI), is a promising source of biomarkers of brain pathologies. However, establishing and using…
In neuroscience, understanding inter-individual differences has recently emerged as a major challenge, for which functional magnetic resonance imaging (fMRI) has proven invaluable. For this, neuroscientists rely on basic methods such as…
By computerized analysis of cortical activity recorded via fMRI for pediatric epilepsy patients, we implement algorithmic localization of epileptic seizure focus within one of eight cortical lobes. Our innovative machine learning techniques…
For random quantum spin models, the strong disorder perturbative expansion of the Local Integrals of Motion (LIOMs) around the real-spin operators is revisited. The emphasis is on the links with other properties of the Many-Body-Localized…
Diagnostic errors remain a major cause of preventable mortality, particularly in resource limited settings. Medical training simulators, including robopatients, help reduce such errors by replicating patient responses during procedures such…
Motor Imagery (MI) is gaining traction in both rehabilitation and sports settings, but its immediate influence on human postural control is not yet clearly understood. The focus of this study is to examine the effects of MI on the dynamics…
Human physical function is governed by self-efficacy, the belief in one's motor capacity. In chronic pain patients, this capacity may remain reduced long after the damage causing the pain has been cured. Chronic pain alters body schema,…
In the literature of cognitive neuroscience, researchers tend to assume a linear relationship between brain activation level and task performance; however, controversial findings have been reported in participants at different ages and…
The local field potential (LFP) is as a measure of the combined activity of neurons within a region of brain tissue. While biophysical modeling schemes for LFP in cortical circuits are well established, there is a paramount lack of…
Functional Magnetic Resonance Imaging~(fMRI) is widely used to study activation in the human brain. In most cases, data are commonly used to construct activation maps corresponding to a given paradigm. Results can be very variable, hence…
Rehabilitation training is the primary intervention to improve motor recovery after stroke, but a tool to measure functional training does not currently exist. To bridge this gap, we previously developed an approach to classify functional…
Functional Magnetic Resonance Imaging~(fMRI) is a popular non-invasive modality to investigate activation in the human brain. The end result of most fMRI experiments is an activation map corresponding to the given paradigm. These maps can…
Creating haptic interfaces capable of rendering the rich sensation needed for dexterous manipulation is crucial for the advancement of human-in-the-loop telerobotic systems (HiLTS). One limiting factor has been the absence of detailed…