相关论文: How transcranial direct current stimulation facili…
Objective: Direct cortical responses (DCR) and axono-cortical evoked potentials (ACEP) are generated by electrically stimulating the cortex either directly or indirectly through white matter pathways, potentially leading to different…
A novel approach is developed for discovering directed connectivity between specified pairs of nodes in a high-dimensional network (HDN) of brain signals. To accurately identify causal connectivity for such specified objectives, it is…
Transcranial electric stimulation (TES) can modulate intrinsic neural activity in the brain by injecting weak currents through electrodes attached to the scalp. TES has been widely used as a neuroscience tool to investigate how behavioural…
Neuronal excitability is known to be affected by transcranial electrical stimulation. However, due to the existence of both excitatory and inhibitory neurons in the cortex, the mechanism of neuronal excitability shift is still not clear.…
Despite the widespread adoption of Backpropagation algorithm-based Deep Neural Networks, the biological infeasibility of the BP algorithm could potentially limit the evolution of new DNN models. To find a biologically plausible algorithm to…
Stroke is the second leading cause of disability worldwide. In order to minimize disability, the goal of stroke treatment is to preserve tissue in the area where blood supply is decreased but sufficient to stave off cell death. Thrombectomy…
Healthy brain networks usually show highly efficient information communication and self-sustained oscillation abilities. However, how the brain network structure affects these dynamics after an injury (stroke) is not very clear. The…
Deep Brain Stimulation (DBS) stands as an effective intervention for alleviating the motor symptoms of Parkinson's disease (PD). Traditional commercial DBS devices are only able to deliver fixed-frequency periodic pulses to the basal…
Objective: Closed-loop deep brain stimulation (DBS) may improve current clinical DBS treatment for neurological movement disorders, but control algorithms may perform differently across patients. New metrics are needed for comparing and…
Deep brain stimulation (DBS) is an established method for treating pathological conditions such as Parkinson's disease, dystonia, Tourette syndrome, and essential tremor. While the precise mechanisms which underly the effectiveness of DBS…
Fractional-order dynamical systems are used to describe processes that exhibit temporal long-term memory and power-law dependence of trajectories. There has been evidence that complex neurophysiological signals like electroencephalogram…
Objective: Numerical modeling of electric fields induced by transcranial alternating current stimulation (tACS) is currently a part of the standard procedure to predict and understand neural response. Quasi-static approximation for electric…
Low-intensity transcranial focused ultrasound (tFUS) is rapidly emerging as a transformative non-invasive brain stimulation (NIBS) modality characterized by high spatial resolution and ability to target deep brain circuits. Unlike…
Despite the rapid advances in Brain-computer Interfacing (BCI) and continuous effort to improve the accuracy of brain decoding systems, the urge for the systems to reconstruct the experiences of the users has been widely acknowledged. This…
Inferring the biophysical parameters of conductance-based models (CBMs) from experimentally accessible recordings remains a central challenge in computational neuroscience. Spike times are the most widely available data, yet they reveal…
Adaptive deep brain stimulation (aDBS) has emerged as a promising treatment for Parkinson disease (PD). In aDBS, a surgically placed electrode sends dynamically altered stimuli to the brain based on neurophysiological feedback: an invasive…
Back-action refers to a response that retro-acts on a system to tailor its properties with respect to an external stimulus. This effect is at the heart of many electronic devices such as amplifiers, oscillators, and sensors. Here, we…
At the macroscale, the brain operates as a network of interconnected neuronal populations, which display rhythmic dynamics that support interareal communication. Understanding how stimulation of a particular brain area impacts such…
Identifying what aspects of brain activity are responsible for conscious perception remains one of the most challenging problems in science. While progress has been made through psychophysical studies employing EEG and fMRI, research would…
Parkinsonism leads to various electrophysiological changes in the basal ganglia-thalamocortical system (BGTCS), often including elevated discharge rates of the subthalamic nucleus (STN) and the output nuclei, and reduced activity of the…