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We investigate the influence of indirect connections, interregional distance and collective effects on the large-scale functional networks of the human cortex. We study topologies of empirically derived resting state networks (RSNs),…

神经元与认知 · 定量生物学 2013-02-18 Vesna Vuksanović , Philipp Hövel

Objective While Alzheimer's disease (AD) and frontotemporal dementia (FTD) show some common memory deficits, these two disorders show partially overlapping complex spatiotemporal patterns of neural dynamics. The objective of this study is…

神经元与认知 · 定量生物学 2025-07-14 Sungwoo Ahn , Evie A. Malaia , Leonid L Rubchinsky

The continuous integration of experimental data into coherent models of the brain is an increasing challenge of modern neuroscience. Such models provide a bridge between structure and activity, and identify the mechanisms giving rise to…

神经元与认知 · 定量生物学 2017-03-03 Jannis Schuecker , Maximilian Schmidt , Sacha J. van Albada , Markus Diesmann , Moritz Helias

The brain can be regarded as a network: a connected system where nodes, or units, represent different specialized regions and links, or connections, represent communication pathways. From a functional perspective communication is coded by…

神经元与认知 · 定量生物学 2014-09-10 Fabrizio De Vico Fallani , Jonas Richiardi , Mario Chavez , Sophie Achard

Understanding the relationship between the structure and function of the human brain is one of the most important open questions in Neurosciences. In particular, Resting State Networks (RSN) and more specifically the Default Mode Network…

The brain continually reorganizes its functional network to adapt to post-stroke functional impairments. Previous studies using static modularity analysis have presented global-level behavior patterns of this network reorganization.…

统计计算 · 统计学 2024-03-25 Kaichao Wu , Beth Jelfs , Katrina Neville , Wenzhen He , Qiang Fang

Human brain maturation is characterized by the prolonged development of structural and functional properties of large-scale networks that extends into adulthood. However, it is not clearly understood which features change and which remain…

神经元与认知 · 定量生物学 2014-04-02 Sol Lim , Cheol E. Han , Peter J. Uhlhaas , Marcus Kaiser

Recent work has shown that multimodal association areas-including frontal, temporal and parietal cortex-are focal points of functional network reconfiguration during human learning and performance of cognitive tasks. On the other hand,…

神经元与认知 · 定量生物学 2016-10-12 F. A. Soto , D. S. Bassett , F. G. Ashby

Brain networks can be defined and explored through their connectivity. Here, we analyzed the relationship between structural connectivity (SC) across 2,514 regions that cover the entire brain and brainstem, and their dynamic functional…

The static synaptic connectivity of neuronal circuits stands in direct contrast to the dynamics of their function. As in changing community interactions, different neurons can participate actively in various combinations to effect behaviors…

神经元与认知 · 定量生物学 2024-02-29 Luciano Dyballa , Samuel Lang , Alexandra Haslund-Gourley , Eviatar Yemini , Steven W. Zucker

Activity in coupled systems is often oscillatory, for example, the firing pattern of neuronal populations. Whereas these oscillations have been studied predominantly in local circuits, here we show how the topology of large-scale networks,…

神经元与认知 · 定量生物学 2014-05-15 Marcus Kaiser

Communication within or between complex systems is commonplace in the natural sciences and fields such as graph neural networks. The brain is a perfect example of such a complex system, where communication between brain regions is…

神经元与认知 · 定量生物学 2022-10-10 Eloy Geenjaar , Noah Lewis , Amrit Kashyap , Robyn Miller , Vince Calhoun

How intelligence emerges from living beings has been a fundamental question in neuroscience. However, it remains largely unanswered due to the complex neuronal dynamics and intricate connections between neurons in real neural systems. To…

神经元与认知 · 定量生物学 2024-09-04 Xiaoyu Zhang , Pengcheng Yang , Jiawei Feng , Qiang Luo , Wei Lin , Xin Lu

We introduce a novel recurrent neural network (RNN) approach to account for temporal dynamics and dependencies in brain networks observed via functional magnetic resonance imaging (fMRI). Our approach directly parameterizes temporal…

神经与进化计算 · 计算机科学 2018-08-28 R Devon Hjelm , Eswar Damaraju , Kyunghyun Cho , Helmut Laufs , Sergey M. Plis , Vince Calhoun

A brain microstate is characterized by a unique, fixed spatial distribution of electrically active neurons with time varying amplitude. It is hypothesized that a microstate implements a functional/physiological state of the brain during…

In this paper, we present a novel and versatile method to study the dynamics of resting-state fMRI brain connectivity with a high temporal sensitivity. Whereas most existing methods often rely on dividing the time-series into larger…

神经元与认知 · 定量生物学 2016-01-14 William Hedley Thompson , Peter Fransson

Complex problem solving is a high level cognitive process which has been thoroughly studied over the last decade. The Tower of London (TOL) is a task that has been widely used to study problem-solving. In this study, we aim to explore the…

神经元与认知 · 定量生物学 2018-10-12 Abdullah Alchihabi , Omer Ekmekci , Baran B. Kivilcim , Sharlene D. Newman , Fatos T. Yarman Vural

The organization of the connectivity between mammalian cortical areas has become a major subject of study, because of its important role in scaffolding the macroscopic aspects of animal behavior and intelligence. In this study we present a…

神经元与认知 · 定量生物学 2007-05-23 Luciano da F Costa , Marcus Kaiser , Claus C Hilgetag

The brain is in a state of perpetual reverberant neural activity, even in the absence of specific tasks or stimuli. Shedding light on the origin and functional significance of such a dynamical state is essential to understanding how the…

统计力学 · 物理学 2022-07-08 Guillermo B. Morales , Serena Di Santo , Miguel A. Munoz

Identifying unusual brain activity is a crucial task in neuroscience research, as it aids in the early detection of brain disorders. It is common to represent brain networks as graphs, and researchers have developed various graph-based…

机器学习 · 计算机科学 2024-10-04 Sadaf Sadeghian , Xiaoxiao Li , Margo Seltzer