相关论文: Decision Support System for Renal Transplantation

Renal patients which have a willing but incompatible donor can decide to participate in a kidney exchange program (KEP). The goal of a KEP is to identify sets of such incompatible pairs that can exchange donors, leading to compatible…

We propose a simulation-optimization-based methodology to improve the way that organ transplant offers are made to potential recipients. Our policy can be applied to all types of organs, is implemented starting at the local level, is…

Numerous tutorials and research papers focus on methods in either survival analysis or causal inference, leaving common complications in medical studies unaddressed. In practice one must handle problems jointly, without the luxury of…

In kidney exchange programs, multiple patient-donor pairs each of whom are otherwise incompatible, exchange their donors to receive compatible kidneys. The Kidney Exchange problem is typically modelled as a directed graph where every vertex…

A Convolutional Neural Network was used to predict kidney function in patients with chronic kidney disease from high-resolution digital pathology scans of their kidney biopsies. Kidney biopsies were taken from participants of the NEPTUNE…

Kidney paired donation programs (KPDPs) match patients with willing but incompatible donors to compatible donors with an assurance that when they donate, their intended recipient receives a kidney in return from a different donor. A patient…

Kidney exchange is a transplant modality that has provided new opportunities for living kidney donation in many countries around the world since 1991. It has been extensively studied from an Operational Research (OR) perspective since 2004.…

Medical institutions are considering the use of LLMs in high-stakes clinical decision-making, such as organ allocation. In such sensitive use cases, evaluating fairness is imperative. However, existing evaluation methods often fall short;…

In this paper we study approaches for dealing with treatment when developing a clinical prediction model. Analogous to the estimand framework recently proposed by the European Medicines Agency for clinical trials, we propose a…

Motivated by kidney exchange, we study the following mechanism-design problem: On a directed graph (of transplant compatibilities among patient-donor pairs), the mechanism must select a simple path (a chain of transplantations) starting at…

The kidney exchange problem (KEP) seeks to find possible exchanges among pairs of patients and their incompatible kidney donors while meeting specific optimization criteria such as maximizing the overall number of possible transplants.…

The goal of a kidney exchange program (KEP) is to maximize number of transplants within a pool of incompatible patient-donor pairs by exchanging donors. A KEP can be modelled as a maximum matching problem in a graph. A KEP between…

Dynamic predictions of survival outcomes are of great interest to physicians and patients, since such predictions are useful elements of clinical decision-making. Joint modelling of longitudinal and survival data has been increasingly used…

In observational studies of survival time featuring a binary time-dependent treatment, the hazard ratio (an instantaneous measure) is often used to represent the treatment effect. However, investigators are often more interested in the…

Kidney exchange programs (KEP's) represent an additional possibility of transplant for patients suffering from end stage kidney disease. If a patient has a willing living donor with whom the patient is not compatible, the pair…

This paper addresses the problem of maximizing the expected size of a matching in the case of unreliable vertices and/or edges. The assumption is that upon failure, remaining vertices that have not been matched may be subject to a new…

The kidney exchange mechanism allows many patient-donor pairs who are otherwise incompatible with each other to come together and exchange kidneys along a cycle. However, due to infrastructure and legal constraints, kidney exchange can only…

Kidney exchange is a barter market where patients trade willing but medically incompatible donors. These trades occur via cycles, where each patient-donor pair both gives and receives a kidney, and via chains, which begin with an altruistic…

To overcome incompatibility issues, kidney patients may swap their donors. In international kidney exchange programmes (IKEPs), countries merge their national patient-donor pools. We consider a recently introduced credit system. In each…

In the query-commit problem we are given a graph where edges have distinct probabilities of existing. It is possible to query the edges of the graph, and if the queried edge exists then its endpoints are irrevocably matched. The goal is to…