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In a recent paper on 'Estimating Species Trees from Unrooted Gene Trees' Liu and Yu observe that the distance matrix on the underlying taxon set, which is built up from expected internode distances on gene trees under the multispecies…

种群与进化 · 定量生物学 2011-08-26 Martin Kreidl

Inference of network-like evolutionary relationships between species from genomic data must address the interwoven signals from both gene flow and incomplete lineage sorting. The heavy computational demands of standard approaches to this…

种群与进化 · 定量生物学 2021-08-05 Elizabeth S. Allman , Hector Baños , John A. Rhodes

We consider the problem of estimating the evolutionary history of a set of species (phylogeny or species tree) from several genes. It is known that the evolutionary history of individual genes (gene trees) might be topologically distinct…

种群与进化 · 定量生物学 2016-11-18 Gautam Dasarathy , Robert Nowak , Sebastien Roch

We introduce a simple algorithm for reconstructing phylogenies from multiple gene trees in the presence of incomplete lineage sorting, that is, when the topology of the gene trees may differ from that of the species tree. We show that our…

种群与进化 · 定量生物学 2011-09-30 Elchanan Mossel , Sebastien Roch

Species tree estimation is a complex problem, due to the fact that different parts of the genome can have different evolutionary histories than the genome itself. One of the causes for this discord is incomplete lineage sorting (also called…

种群与进化 · 定量生物学 2019-04-09 Erin Molloy , Tandy Warnow

In order to conduct a statistical analysis on a given set of phylogenetic gene trees, we often use a distance measure between two trees. In a statistical distance-based method to analyze discordance between gene trees, it is a key to decide…

种群与进化 · 定量生物学 2016-02-05 Jing Xi , Jin Xie , Ruriko Yoshida

One approach to estimating a species tree from a collection of gene trees is to first estimate probabilities of clades from the gene trees, and then to construct the species tree from the estimated clade probabilities. While a greedy…

种群与进化 · 定量生物学 2012-11-14 Elizabeth S. Allman , James H. Degnan , John A. Rhodes

The reconstruction of a species phylogeny from genomic data faces two significant hurdles: 1) the trees describing the evolution of each individual gene--i.e., the gene trees--may differ from the species phylogeny and 2) the molecular…

机器学习 · 计算机科学 2017-07-17 Gautam Dasarathy , Elchanan Mossel , Robert Nowak , Sebastien Roch

The log-det distance between two aligned DNA sequences was introduced as a tool for statistically consistent inference of a gene tree under simple non-mixture models of sequence evolution. Here we prove that the log-det distance, coupled…

种群与进化 · 定量生物学 2018-06-14 Elizabeth S. Allman , Colby Long , John A. Rhodes

Using topological summaries of gene trees as a basis for species tree inference is a promising approach to obtain acceptable speed on genomic-scale datasets, and to avoid some undesirable modeling assumptions. Here we study the…

种群与进化 · 定量生物学 2017-04-17 Elizabeth S. Allman , James H. Degnan , John A. Rhodes

Understanding the evolution of a set of genes or species is a fundamental problem in evolutionary biology. The problem we study here takes as input a set of trees describing {possibly discordant} evolutionary scenarios for a given set of…

数据结构与算法 · 计算机科学 2019-07-10 Cedric Chauve , Mark Jones , Manuel Lafond , Céline Scornavacca , Mathias Weller

Species networks generalize the notion of species trees to allow for hybridization or other lateral gene transfer. Under the Network Multispecies Coalescent Model, individual gene trees arising from a network can have any topology, but…

种群与进化 · 定量生物学 2019-05-20 Elizabeth Allman , Hector Banos , John Rhodes

Gene trees are evolutionary trees representing the ancestry of genes sampled from multiple populations. Species trees represent populations of individuals -- each with many genes -- splitting into new populations or species. The coalescent…

种群与进化 · 定量生物学 2010-07-30 Elizabeth S. Allman , James H. Degnan , John A. Rhodes

As researchers collect increasingly large molecular data sets to reconstruct the Tree of Life, the heterogeneity of signals in the genomes of diverse organisms poses challenges for traditional phylogenetic analysis. A class of phylogenetic…

种群与进化 · 定量生物学 2015-09-11 Liang Liu , Zhenxiang Xi , Shaoyuan Wu , Charles Davis , Scott V. Edwards

Reconstructing the tree of life from molecular sequences is a fundamental problem in computational biology. Modern data sets often contain a large number of genes, which can complicate the reconstruction problem due to the fact that…

概率论 · 数学 2017-07-21 Constantinos Daskalakis , Sebastien Roch

In this paper, we consider a tree inference problem motivated by the critical problem in single-cell genomics of reconstructing dynamic cellular processes from sequencing data. In particular, given a population of cells sampled from such a…

统计方法学 · 统计学 2025-07-16 Elodie Maignant , Tim Conrad , Christoph von Tycowicz

The inference of the evolutionary history of a collection of organisms is a problem of fundamental importance in evolutionary biology. The abundance of DNA sequence data arising from genome sequencing projects has led to significant…

种群与进化 · 定量生物学 2015-07-07 Julia Chifman , Laura Kubatko

With advances in sequencing technologies, there are now massive amounts of genomic data from across all life, leading to the possibility that a robust Tree of Life can be constructed. However, "gene tree heterogeneity", which is when…

种群与进化 · 定量生物学 2018-03-08 Sebastien Roch , Michael Nute , Tandy Warnow

Phylogenetic networks extend phylogenetic trees to model non-vertical inheritance, by which a lineage inherits material from multiple parents. The computational complexity of estimating phylogenetic networks from genome-wide data with…

种群与进化 · 定量生物学 2022-06-28 Jingcheng Xu , Cécile Ané

We consider the reconstruction of a phylogeny from multiple genes under the multispecies coalescent. We establish a connection with the sparse signal detection problem, where one seeks to distinguish between a distribution and a mixture of…

概率论 · 数学 2017-07-24 Elchanan Mossel , Sebastien Roch
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