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The analysis of data from multiple experiments, such as observations of several individuals, is commonly approached using mixed-effects models, which account for variation between individuals through hierarchical representations. This makes…

统计计算 · 统计学 2026-03-05 Henrik Häggström , Sebastian Persson , Marija Cvijovic , Umberto Picchini

We present a novel approach for training deep neural networks in a Bayesian way. Classical, i.e. non-Bayesian, deep learning has two major drawbacks both originating from the fact that network parameters are considered to be deterministic.…

机器学习 · 统计学 2019-03-11 Konstantin Posch , Jan Steinbrener , Jürgen Pilz

An epidemic model where disease transmission can occur either through global contacts or through local, nearest neighbor interactions is considered. The classical SIR--model describing the global interactions is extended by adding…

种群与进化 · 定量生物学 2022-02-02 Thomas Götz

Distribution regression has recently attracted much interest as a generic solution to the problem of supervised learning where labels are available at the group level, rather than at the individual level. Current approaches, however, do not…

机器学习 · 统计学 2021-01-18 Ho Chung Leon Law , Danica J. Sutherland , Dino Sejdinovic , Seth Flaxman

Infectious diseases remain one of the major causes of human mortality and suffering. Mathematical models have been established as an important tool for capturing the features that drive the spread of the disease, predicting the progression…

Stochastic infectious disease models capture uncertainty in public health outcomes and have become increasingly popular in epidemiological practice. However, calibrating these models to observed data is challenging with existing methods for…

统计方法学 · 统计学 2024-12-18 Prayag Chatha , Fan Bu , Jeffrey Regier , Evan Snitkin , Jon Zelner

Tracking the spread of infectious disease during a pandemic has posed a great challenge to the governments and health sectors on a global scale. To facilitate informed public health decision-making, the concerned parties usually rely on…

统计方法学 · 统计学 2023-06-05 Tejasv Bedi , Yanxun Xu , Qiwei Li

Compartmental models, especially the Susceptible-Infected-Removed (SIR) model, have long been used to understand the behaviour of various diseases. Allowing parameters, such as the transmission rate, to be time-dependent functions makes it…

统计方法学 · 统计学 2024-09-27 Son Luu , Edward Susko , Lam Si Tung Ho

Edge-based network models, especially those based on bond percolation methods, can be used to model disease transmission on complex networks and accommodate social heterogeneity while keeping tractability. Here we present an application of…

种群与进化 · 定量生物学 2024-10-18 S. Zhao , S. Saeed , M. Carter , B. Stoner , M. Hoover , H. Guan , F. M. G. Magpantay

Epidemiological models contain a set of parameters that must be adjusted based on available observations. Once a model has been calibrated, it can be used as a forecasting tool to make predictions and to evaluate contingency plans. It is…

We propose a general method to carry out a valid Bayesian analysis of a finite-dimensional `targeted' parameter in the presence of a finite-dimensional nuisance parameter. We apply our methods to causal inference based on estimating…

统计方法学 · 统计学 2026-02-03 Magid Sabbagh , David A. Stephens

In segmentation problems, inference on change-point position and model selection are two difficult issues due to the discrete nature of change-points. In a Bayesian context, we derive exact, non-asymptotic, explicit and tractable formulae…

统计计算 · 统计学 2015-12-31 Guillem Rigaill , Emilie Lebarbier , Stéphane Robin

Sequential probabilistic inference from streaming observations requires modeling distributions over future trajectories as new observations arrive. Although diffusion and flow-matching models are effective at capturing high-dimensional,…

机器学习 · 计算机科学 2026-05-15 Yinan Huang , Hans Hao-Hsun Hsu , Junran Wang , Bo Dai , Pan Li

In this paper, we present an approach for modeling bio-tissues that incorporates the variability in properties as part of their characteristics. This is achieved by considering the parameters of the model of a biomaterial to themselves be…

组织与器官 · 定量生物学 2013-12-11 Srikrishna Doraiswamy , Arun R. Srinivasa

Interactions among people or objects are often dynamic in nature and can be represented as a sequence of networks, each providing a snapshot of the interactions over a brief period of time. An important task in analyzing such evolving…

社会与信息网络 · 计算机科学 2016-06-17 Leto Peel , Aaron Clauset

Joint modelling of longitudinal observations and event times continues to remain a topic of considerable interest in biomedical research. For example, in HIV studies, the longitudinal bio-marker such as CD4 cell count in a patient's blood…

统计方法学 · 统计学 2024-07-19 Srimanti Dutta , Arindom Chakraborty , Dipankar Bandyopadhyay

Epidemic models are invaluable tools to understand and implement strategies to control the spread of infectious diseases, as well as to inform public health policies and resource allocation. However, current modeling approaches have…

统计方法学 · 统计学 2026-05-12 Caitlin Ward , Rob Deardon , Alexandra M. Schmidt

Background: Recently developed techniques to study the spread of infectious diseases through networks make assumptions that the initial proportion infected is infinitesimal and the population behavior is static throughout the epidemic. The…

种群与进化 · 定量生物学 2012-08-17 Joel C. Miller

Despite being similar in structure, functioning, and size viral pathogens enjoy very different mostly well-defined ways of life. They occupy their hosts for a few days (influenza), for a few weeks (measles), or even lifelong (HCV), which…

种群与进化 · 定量生物学 2020-05-01 Alexander Lange

Survival models are used in various fields, such as the development of cancer treatment protocols. Although many statistical and machine learning models have been proposed to achieve accurate survival predictions, little attention has been…

机器学习 · 计算机科学 2020-03-26 Hrushikesh Loya , Pranav Poduval , Deepak Anand , Neeraj Kumar , Amit Sethi