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Tree rearrangement operations typically induce a metric on the space of phylogenetic trees. One important property of these metrics is the size of the neighbourhood, that is, the number of trees exactly one operation from a given tree. We…

组合数学 · 数学 2012-02-13 Peter J. Humphries , Taoyang Wu

Species tree reconstruction from genomic data is increasingly performed using methods that account for sources of gene tree discordance such as incomplete lineage sorting. One popular method for reconstructing species trees from unrooted…

种群与进化 · 定量生物学 2017-12-06 Shubhanshu Shekhar , Sebastien Roch , Siavash Mirarab

Maximum parsimony distance is a measure used to quantify the dissimilarity of two unrooted phylogenetic trees. It is NP-hard to compute, and very few positive algorithmic results are known due to its complex combinatorial structure. Here we…

数据结构与算法 · 计算机科学 2020-04-07 Mark Jones , Steven Kelk , Leen Stougie

Rooted phylogenetic networks are rooted acyclic digraphs. They are used to model complex evolution where hybridization, recombination and other reticulation events play important roles. A rigorous definition of network compression is…

数据结构与算法 · 计算机科学 2019-03-05 Andreas D. M. Gunawan , Hongwei Yan , Louxin Zhang

The Treewidth-2 Vertex Deletion problem asks whether a set of at most $t$ vertices can be removed from a graph, such that the resulting graph has treewidth at most two. A graph has treewidth at most two if and only if it does not contain a…

数据结构与算法 · 计算机科学 2022-03-21 Jeroen L. G. Schols

The {\sc $k$-Leaf Out-Branching} problem is to find an out-branching (i.e. a rooted oriented spanning tree) with at least $k$ leaves in a given digraph. The problem has recently received much attention from the viewpoint of parameterized…

数据结构与算法 · 计算机科学 2008-11-06 Henning Fernau , Fedor V. Fomin , Daniel Lokshtanov , Daniel Raible , Saket Saurabh , Yngve Villanger

A branch-and-bound (BB) tree certifies a dual bound on the value of an integer program. In this work, we introduce the tree compression problem (TCP): Given a BB tree T that certifies a dual bound, can we obtain a smaller tree with the same…

最优化与控制 · 数学 2023-06-08 Gonzalo Muñoz , Joseph Paat , Álinson S. Xavier

The problem of reconstructing evolutionary trees or phylogenies is of great interest in computational biology. A popular model for this problem assumes that we are given the set of leaves (current species) of an unknown binary tree and the…

数据结构与算法 · 计算机科学 2022-06-16 Eshwar Ram Arunachaleswaran , Anindya De , Sampath Kannan

In phylogenetics, distances are often used to measure the incongruence between a pair of phylogenetic trees that are reconstructed by different methods or using different regions of genome. Motivated by the maximum parsimony principle in…

种群与进化 · 定量生物学 2016-07-08 Steven Kelk , Mareike Fischer , Vincent Moulton , Taoyang Wu

Phylogenetic networks are a special type of graph which generalize phylogenetic trees and that are used to model non-treelike evolutionary processes such as recombination and hybridization. In this paper, we consider {\em unrooted}…

组合数学 · 数学 2025-05-21 Katharina T. Huber , Simone Linz , Vincent Moulton

The Steiner Tree problem is a classical problem in combinatorial optimization: the goal is to connect a set $T$ of terminals in a graph $G$ by a tree of minimum size. Karpinski and Zelikovsky (1996) studied the $\delta$-dense version of…

数据结构与算法 · 计算机科学 2020-04-30 Marek Karpinski , Mateusz Lewandowski , Syed Mohammad Meesum , Matthias Mnich

Frequent tree mining asks us to enumerate tree patterns that occur frequently in a database of rooted trees. This problem is motivated by tree-structured data in bioinformatics, such as glycans and pseudoknot-free RNA secondary structures.…

数据结构与算法 · 计算机科学 2026-05-21 Kenta Komoto , Kazuhiro Kurita , Hirotaka Ono

We present the first fixed-parameter algorithm for constructing a tree-child phylogenetic network that displays an arbitrary number of binary input trees and has the minimum number of reticulations among all such networks. The algorithm…

离散数学 · 计算机科学 2019-07-22 Leo van Iersel , Remie Janssen , Mark Jones , Yukihiro Murakami , Norbert Zeh

For an undirected tree with $n$ edges labelled by single letters, we consider its substrings, which are labels of the simple paths between pairs of nodes. We prove that there are $O(n^{1.5})$ different palindromic substrings. This solves an…

数据结构与算法 · 计算机科学 2020-11-30 Paweł Gawrychowski , Tomasz Kociumaka , Wojciech Rytter , Tomasz Waleń

Recently there has been considerable interest in the problem of finding a phylogenetic network with a minimum number of reticulation vertices which displays a given set of phylogenetic trees, that is, a network with minimum hybrid number.…

离散数学 · 计算机科学 2021-04-13 Katharina T. Huber , Simone Linz , Vincent Moulton

Here we present a new fixed parameter tractable algorithm to compute the hybridization number r of two rooted, not necessarily binary phylogenetic trees on taxon set X in time (6^r.r!).poly(n)$, where n=|X|. The novelty of this approach is…

定量方法 · 定量生物学 2012-07-26 Teresa Piovesan , Steven Kelk

Phylogenetic networks are rooted directed acyclic graphs that represent evolutionary relationships between species whose past includes reticulation events such as hybridisation and horizontal gene transfer. To search the space of…

组合数学 · 数学 2019-04-09 Jonathan Klawitter , Simone Linz

We study the CONNECTED \eta-TREEDEPTH DELETION problem where the input instance is an undireted graph G = (V, E) and an integer k. The objective is to decide if G has a set S \subseteq V(G) of at most k vertices such that G - S has…

数据结构与算法 · 计算机科学 2022-12-02 Eduard Eiben , Diptapriyo Majumdar , M. S. Ramanujan

Compatibility of unrooted phylogenetic trees is a well studied problem in phylogenetics. It asks to determine whether for a set of k input trees there exists a larger tree (called a supertree) that contains the topologies of all k input…

离散数学 · 计算机科学 2014-03-03 Alexander Grigoriev , Steven Kelk , Nela Lekic

Phylogenetic networks are directed acyclic graphs that depict the genomic evolution of related taxa. Reticulation nodes in such networks (nodes with more than one parent) represent reticulate evolutionary events, such as recombination,…

种群与进化 · 定量生物学 2024-11-21 Alexey Markin , Sriram Vijendran , Oliver Eulenstein