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When making treatment selection decisions, it is essential to include a causal effect estimation analysis to compare potential outcomes under different treatments or controls, assisting in optimal selection. However, merely estimating…

机器学习 · 统计学 2024-10-08 Sherly Alfonso-Sánchez , Kristina P. Sendova , Cristián Bravo

Personalized medicine, a paradigm of medicine tailored to a patient's characteristics, is an increasingly attractive field in health care. An important goal of personalized medicine is to identify a subgroup of patients, based on baseline…

机器学习 · 统计学 2023-01-31 Hengrui Cai , Wenbin Lu , Rachel Marceau West , Devan V. Mehrotra , Lingkang Huang

The effect of vigorous physical activity on mortality in the elderly is difficult to estimate using conventional approaches to causal inference that define this effect by comparing the mortality risks corresponding to hypothetical scenarios…

应用统计 · 统计学 2007-12-18 Oliver Bembom , Mark J. van der Laan

Policy optimization methods have shown great promise in solving complex reinforcement and imitation learning tasks. While model-free methods are broadly applicable, they often require many samples to optimize complex policies. Model-based…

人工智能 · 计算机科学 2017-11-23 Daniel Levy , Stefano Ermon

A treatment regime is a deterministic function that dictates personalized treatment based on patients' individual prognostic information. There is a fast-growing interest in finding optimal treatment regimes to maximize expected long-term…

统计理论 · 数学 2016-11-25 Runchao Jiang , Wenbin Lu , Rui Song , Marie Davidian

The paper focuses on identifying the causes of student performance to provide personalized recommendations for improving pass rates. We introduce the need to move beyond predictive models and instead identify causal relationships. We…

计算机与社会 · 计算机科学 2023-09-26 Bevan I. Smith

Modeling disease progression through multiple stages is critical for clinical decision-making for chronic diseases, e.g., cancer, diabetes, chronic kidney diseases, and so on. Existing approaches often model the disease progression as a…

机器学习 · 计算机科学 2025-03-04 Haoyu Yang , Sanjoy Dey , Pablo Meyer

In the social and health sciences, researchers often make causal inferences using sensitive variables. These researchers, as well as the data holders themselves, may be ethically and perhaps legally obligated to protect the confidentiality…

统计方法学 · 统计学 2024-08-28 Sharmistha Guha , Jerome P. Reiter

A pressing challenge in medical research is to identify optimal treatments for individual patients. This is particularly challenging in mental health settings where mean responses are often similar across multiple treatments. For example,…

统计方法学 · 统计学 2022-03-08 Lanqiu Yao , Thaddeus Tarpey

Randomized controlled trials typically analyze the effectiveness of treatments with the goal of making treatment recommendations for patient subgroups. With the advance of electronic health records, a great variety of data has been…

机器学习 · 计算机科学 2021-03-31 Zhiliang Wu , Yinchong Yang , Yunpu Ma , Yushan Liu , Rui Zhao , Michael Moor , Volker Tresp

Researchers commonly use difference-in-differences (DiD) designs to evaluate public policy interventions. While methods exist for estimating effects in the context of binary interventions, policies often result in varied exposures across…

统计方法学 · 统计学 2025-02-07 Gary Hettinger , Youjin Lee , Nandita Mitra

Identifying and measuring biases associated with sensitive attributes is a crucial consideration in healthcare to prevent treatment disparities. One prominent issue is inaccurate pulse oximeter readings, which tend to overestimate oxygen…

机器学习 · 计算机科学 2026-01-27 Kevin Zhang , Yonghan Jung , Divyat Mahajan , Karthikeyan Shanmugam , Shalmali Joshi

When training machine learning (ML) models for potential deployment in a healthcare setting, it is essential to ensure that they do not replicate or exacerbate existing healthcare biases. Although many definitions of fairness exist, we…

机器学习 · 计算机科学 2026-01-21 Aparajita Kashyap , Sara Matijevic , Noémie Elhadad , Steven A. Kushner , Shalmali Joshi

Explicit and implicit bias clouds human judgement, leading to discriminatory treatment of minority groups. A fundamental goal of algorithmic fairness is to avoid the pitfalls in human judgement by learning policies that improve the overall…

机器学习 · 计算机科学 2020-11-02 Yuzi He , Keith Burghardt , Siyi Guo , Kristina Lerman

This paper focuses on developing Pareto-optimal estimation and policy learning to identify the most effective treatment that maximizes the total reward from both short-term and long-term effects, which might conflict with each other. For…

机器学习 · 计算机科学 2024-03-13 Yingrong Wang , Anpeng Wu , Haoxuan Li , Weiming Liu , Qiaowei Miao , Ruoxuan Xiong , Fei Wu , Kun Kuang

We consider optimal regimes for algorithm-assisted human decision-making. Such regimes are decision functions of measured pre-treatment variables and, by leveraging natural treatment values, enjoy a "superoptimality" property whereby they…

统计方法学 · 统计学 2024-02-23 Mats J. Stensrud , Julien Laurendeau , Aaron L. Sarvet

Practitioners in diverse fields such as healthcare, economics and education are eager to apply machine learning to improve decision making. The cost and impracticality of performing experiments and a recent monumental increase in electronic…

机器学习 · 计算机科学 2023-08-01 Fredrik D. Johansson , Uri Shalit , Nathan Kallus , David Sontag

Sequential experimental design to discover interventions that achieve a desired outcome is a key problem in various domains including science, engineering and public policy. When the space of possible interventions is large, making an…

机器学习 · 计算机科学 2023-08-17 Jiaqi Zhang , Louis Cammarata , Chandler Squires , Themistoklis P. Sapsis , Caroline Uhler

Difference-in-differences estimation is a widely used method of program evaluation. When treatment is implemented in different places at different times, researchers often use two-way fixed effects to control for location-specific and…

综合经济学 · 经济学 2021-03-25 Pamela Jakiela

For many complex diseases, there is a wide variety of ways in which an individual can manifest the disease. The challenge of personalized medicine is to develop tools that can accurately predict the trajectory of an individual's disease,…

机器学习 · 统计学 2016-01-22 Peter Schulam , Suchi Saria