相关论文: Computational study of geometric effects of bottom…
We report and analyse the results of extensive discrete element method simulations of three-dimensional gravity driven flows of cohesionless granular media over an erodible bed, the whole being confined between two flat and frictional…
Liquid water within the cathode Gas Diffusion Layer (GDL) and Gas Channel (GC) of Proton Exchange Membrane Fuel Cells (PEMFCs) is strongly coupled to gas transport properties, thereby affecting the electrochemical conversion rates. In this…
A microfluidic device is constructed from PDMS with a single channel having a short section that is a thin flexible membrane, in order to investigate the complex fluid-structure interaction that arises between a flowing fluid and a…
We present experimental results on slow flow properties of a granular assembly confined in a vertical column and driven upwards at a constant velocity V. For monodisperse assemblies this study evidences at low velocities ($1<V<100 \mu m/s$)…
Granular materials react to shear stresses differently than do ordinary fluids. Rather than deforming uniformly, materials such as dry sand or cohesionless powders develop shear bands: narrow zones containing large relative particle motion…
We perform molecular dynamics simulations to characterize the occurrence of inhomogeneous shear flows in soft jammed materials. We use rough walls to impose a simple shear flow and study the athermal motion of jammed assemblies of soft…
Inertial focusing in curved microfluidic ducts exploits the interaction of drag force from the Dean flow with the inertial lift force to separate particles or cells laterally across the cross-section width according to their size.…
A new type of water droplet transportation on microstructured hydrophobic surface is proposed and investigated experimentally and theoretically - water droplet could be driven by scale effect which is different from the traditional methods.…
A number of factors, such as, cell-cell interactions and self-propulsion of cells driven by cytoskeletal forces determine tissue morphologies and dynamics. To explore the interplay between these factors in controlling the dynamics at the…
We examine how the shape of cells and the geometry of experiment affect the reaction-diffusion kinetics at the binding between target and probe molecules on molecular biochips. In particular, we compare the binding kinetics for the probes…
Contraction assay based on surface measurement have been widely used to evaluate cell contractility in 3D models. This method is straightforward and requires no specific equipment, but it does not provide quantitative data about contraction…
The migratory dynamics of cells can be influenced by the complex micro-environment through which they move. It remains unclear how the motility machinery of confined cells responds and adapts to their micro-environment. Here, we propose a…
Coordinated cellular movements are key processes in tissue morphogenesis. Using a cell-based modeling approach we study the dynamics of epithelial layers lining surfaces with constant and varying curvature. We demonstrate that extrinsic…
Surface effects become important in microfluidic setups because the surface to volume ratio becomes large. In such setups the surface roughness is not any longer small compared to the length scale of the system and the wetting properties of…
Several meters below the coastal ocean surface there are areas of high ecological activity that contain thin layers of concentrated motile phytoplankton. Gyrotactic trapping has been proposed as a potential mechanism for layer formation of…
Viscous flows through configurations manufactured from soft materials apply both pressure and shear stress at the solid-liquid interface, leading to deformation of the cross-section, which affects the flow rate-pressure drop relation.…
We report on an investigation of the vertical transport of tracer particles released within a shallow, continuously-forced flow by means of numerical simulations. The investigation is motivated by the shallow flows encountered in many…
Motility is a fundamental survival strategy of bacteria to navigate porous environments. Swimming cells thrive in quiescent wetlands and sediments at the bottom of the marine water column, where they mediate many essential biogeochemical…
The measurement of cellular traction forces on soft elastic substrates has become a standard tool for many labs working on mechanobiology. Here we review the basic principles and different variants of this approach. In general, the…
Through high-fidelity numerical simulation, the simple shear flow over regularly arranged micro pillars has been investigated. The essential issues to be addressed include the characteristics of a simple shear flow over quadrilateral array…