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The development of novel texture adaptations for the management of swallowing disorders could be accelerated if reliable in vitro tests were made available. This study addresses some of the limitations of swallowing in vitro models, by…

医学物理 · 物理学 2020-03-04 Marco Marconati , Silvia Pani , Jan Engmann , Adam Burbidge , Marco Ramaioli

Swallowing disorders deteriorate significantly the quality of life and can be lifethreatening. Texture modification using shear thinning food thickeners have proven effective in the management of dysphagia. Some studies have recently…

组织与器官 · 定量生物学 2020-01-23 Marco Marconati , Marco Ramaioli

Shear cell tests have been conducted on twenty different lactose powders, most of which commercially available for oral or inhalation purposes, spanning a wide range of particle sizes, particle morphologies, production processes. The aims…

软凝聚态物质 · 物理学 2025-08-26 Giulio Cavalli , Roberto Bosi , Alessandro Ghiretti , Ciro Cottini , Andrea Benassi , Roberto Gaspari

Inhalation drug delivery has seen a swift rise in the use of dry powder inhalers (DPIs) to treat chronic respiratory conditions. However, universal adoption of DPIs has been restrained due to their low efficiencies and significant drug…

We adopt a Quality by Design (QbD) paradigm to better control the mechanical properties of tablets. To this end, the effect of particle size distribution, lubricant concentration, and mixing time on the tensile strength and elastic modulus…

材料科学 · 物理学 2018-01-09 Sonia M. Razavi , Marcial Gonzalez , Alberto M. Cuitiño

Encapsulation of chemicals using polymer membranes enables to control their transport and delivery for applications such as agrochemistry or detergency. To rationalize the design of polymer capsules, it is necessary to understand how the…

软凝聚态物质 · 物理学 2018-12-18 Corentin Tregouët , Thomas Salez , Mathilde Reyssat , Cécile Monteux

Dense suspensions of soft colloidal particles display a broad range of physical and rheological properties which are still far from being fully understood. To elucidate the role of deformability on colloidal flow, we employ computer…

软凝聚态物质 · 物理学 2018-08-31 M. Foglino , A. N. Morozov , D. Marenduzzo

Microfluidic channels have emerged as useful tools to control dynamic forcing on transported microscale objects, as encountered in emulsions, biological flows, and other soft matter systems. Tailored channel designs enable precise…

软凝聚态物质 · 物理学 2026-05-29 Matteo Milani , Joshua D. McGraw , Anke Lindner Stefano Aime

Molecular dynamics simulations are a powerful tool to study diffusion processes in battery electrolyte and electrode materials. From a single molecular dynamics simulation many properties relevant to diffusion can be obtained, including the…

化学物理 · 物理学 2018-07-09 Niek J. J. de Klerk , Eveline van der Maas , Marnix Wagemaker

Protein-stabilised emulsions can be seen as mixtures of unadsorbed proteins and of protein-stabilised droplets. To identify the contributions of these two components to the overall viscosity of sodium caseinate o/w emulsions, the…

软凝聚态物质 · 物理学 2019-01-30 Marion Roullet , Paul S. Clegg , William J. Frith

Heterogeneous multiscale methods (HMM) combine molecular accuracy of particle-based simulations with the computational efficiency of continuum descriptions to model flow in soft matter liquids. In these schemes, molecular simulations…

Many suspensions contain particles with complex shapes that are affected not only by hydrodynamics, but also by thermal fluctuations, internal kinematic constraints and other long-range non-hydrodynamic interactions. Modeling these systems…

软凝聚态物质 · 物理学 2025-07-31 Blaise Delmotte , Florencio Balboa Usabiaga

Chemical multisensor devices need calibration algorithms to estimate gas concentrations. Their possible adoption as indicative air quality measurements devices poses new challenges due to the need to operate in continuous monitoring modes…

人工智能 · 计算机科学 2020-02-14 S. De Vito , E. Esposito , M. Salvato , O. Popoola , F. Formisano , R. Jones , G. Di Francia

The research is aimed at creating a method for rheological testing of viscoelastic fluids, the droplets of which, when stretched, form thinning filaments, i.e. exhibit the property of spinning. The typical example of such fluid is oral…

医学物理 · 物理学 2021-12-16 Aleksey Rozhkov

After swallowing a liquid or a semi-liquid food product, a thin film responsible for the dynamic profile of aroma release coats the pharyngeal mucosa. The objective of the present article was to understand and quantify physical mechanisms…

Binary droplet collisions are of importance in a variety of practical applications comprising dispersed two-phase flows. The background of our research is the prediction of properties of particulate products formed in spray processes. To…

流体动力学 · 物理学 2012-10-24 C. Focke , D. Bothe , M. Kuschel , M. Sommerfeld

Soft particles such as microgels and core-shell particles can undergo significant and anisotropic deformations when adsorbed to a liquid interface. This, in turn, leads to a complex phase behavior upon compression. Here we develop a…

Protein-stabilised emulsion gels can be studied in the theoretical framework of colloidal gels, because both protein assemblies and droplets may be considered as soft colloids. These particles differ in their nature, size and softness, and…

软凝聚态物质 · 物理学 2020-07-10 Marion Roullet , Paul S. Clegg , William J. Frith

Multivariate data analysis and machine-learning classification become popular tools to extract features without physical models for complex environments recognition. For electronic noses, time sampling over multiple sensors must be a fair…

软凝聚态物质 · 物理学 2023-08-25 Wiem Haj Ammar , Aicha Boujnah , Aimen Boubaker , Adel Kalboussi , Kamal Lmimouni , Sébastien Pecqueur

Real-time monitoring of the gastrointestinal tract in a safe and comfortable manner is valuable for the diagnosis and therapy of many diseases. Within this realm, our review captures the trends in ingestible capsule systems with a focus on…

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