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The phase behavior is investigated for systems composed of a large number of macromolecular components N, with N greater or equal to 2. Liquid-liquid phase separation is modelled using a virial expansion up to the second order of the…

软凝聚态物质 · 物理学 2024-05-29 Arjen Bot , Erik van der Linden , Paul Venema

This chapter summarizes several approaches combining theory, simulation and experiment that aim for a better understanding of phenomena in lipid bilayers and membrane protein systems, covering topics such as lipid rafts, membrane mediated…

生物物理 · 物理学 2014-12-17 Markus Deserno , Kurt Kremer , Harald Paulsen , Christine Peter , Friederike Schmid

Phase separation between two fluids in two-dimensions is investigated by means of Direct Numerical Simulations of coupled Navier-Stokes and Cahn-Hilliard equations. We study the phase ordering process in the presence of an external stirring…

混沌动力学 · 物理学 2009-11-11 S. Berti , G. Boffetta , M. Cencini , A. Vulpiani

Liquid-liquid phase separation has emerged as a fundamental mechanism underlying intracellular organization, with evidence for it being reported in numerous different systems. However, there is a growing concern regarding the lack of…

软凝聚态物质 · 物理学 2022-12-09 Mrityunjay Kothari , Tal Cohen

Solvent-based techniques usually involve preparing dilute blends of electron-donor and electron-acceptor materials dissolved in a volatile solvent. After some form of coating onto a substrate, the solvent evaporates. An initially…

介观与纳米尺度物理 · 物理学 2012-03-01 Olga Wodo , Baskar Ganapathysubramanian

We present an adaptive variational procedure for unstructured meshes to capture fluid-fluid interfaces in two-phase flows. The two phases are modeled by the phase-field finite element formulation, which involves the conservative Allen-Cahn…

流体动力学 · 物理学 2018-07-05 Vaibhav Joshi , Rajeev K. Jaiman

Multicomponent lipid mixtures exhibit complex phase behavior, including coexistence of nanoscopic fluid phases in ternary mixtures mimicking the composition of the outer leaflet of mammalian plasma membrane. The physical mechanisms…

软凝聚态物质 · 物理学 2011-06-01 Frederick A. Heberle , Gerald W. Feigenson

In this work, we review previously developed coarse-grained (CG) particle models for biological membrane and red blood cells (RBCs) and discuss the advantages of the CG particle method over the continuum and atomic simulations on modeling…

软凝聚态物质 · 物理学 2017-07-18 He Li , Hung-yu Chang , Jun Yang , Lu Lu , George Lykotrafitis

There is some literature on the application of linear boundary element method (BEM) for real-time simulation of biological organs. However, literature is scant when it comes to the application of nonlinear BEM, although there is a…

计算工程、金融与科学 · 计算机科学 2024-05-10 Kirana Kumara P

The development of complex multicellular organisms from a single parent cell is a highly orchestrated process that cells conduct collectively without central guidance, creating intricate dynamic patterns essential for development and…

软凝聚态物质 · 物理学 2025-05-29 Siavash Monfared , Aleksandra Ardaševa , Amin Doostmohammadi

The process of programmed cell death, namely apoptosis, is a natural mechanism that regulates healthy tissue, multicellular structures, and homeostasis. An improved understanding of apoptosis can significantly enhance our knowledge of…

In this paper, we consider the numerical approximation for a diffuse interface model of the two-phase incompressible inductionless magnetohydrodynamics problem. This model consists of Cahn-Hilliard equations, Navier-Stokes equations and…

数值分析 · 数学 2022-02-01 Xiaorong Wang , Xiaodi Zhang

We introduce a novel model, comprising self-avoiding surfaces and incorporating edges and tubules, that is designed to characterize the structural morphologies and transitions observed within the endoplasmic reticulum (ER). By employing…

软凝聚态物质 · 物理学 2024-04-09 Jaya Kumar Alageshan , Yashodhan Hatwalne , Rahul Pandit

Understanding the flow of deformable particles such as liquid drops, synthetic capsules and vesicles, and biological cells confined in a small channel is essential to a wide range of potential chemical and biomedical engineering…

流体动力学 · 物理学 2020-11-18 J. M. Lyu , Paul G. Chen , G. Boedec , M. Leonetti , M. Jaeger

Phase field methods have been widely used to study phase transitions and polarization switching in ferroelectric thin films. In this paper, we develop an efficient numerical scheme for the variational phase field model based on variational…

计算物理 · 物理学 2020-12-22 Ruotai Li , Qiang Du , Lei Zhang

We study the coarsening of strongly microphase separated membrane domains in the presence of recycling of material. We study the dynamics of the domain size distribution under both scale-free and size-dependent recycling. Closed form…

亚细胞过程 · 定量生物学 2018-05-11 S. Alex Rautu , G. Rowlands , M. S. Turner

In the microscopic modeling of new-generation electronic quantum nanodevices a variety of simulation strategies have been proposed and employed. Aim of this Letter is to point out virtues versus intrinsic limitations of non-Markovian…

介观与纳米尺度物理 · 物理学 2016-01-28 Rita Claudia Iotti , Fausto Rossi

Inspired by recent experiments, we present a phase-field model of microphase separation in an elastomer swollen with a solvent. The imbalance between the molecular scale of demixing and the mesoscopic scale beyond which elasticity operates…

软凝聚态物质 · 物理学 2025-09-05 Manu Mannattil , Haim Diamant , David Andelman

Numerical simulations of brittle fracture using phase-field approaches often employ a discrete approximation framework that applies the same order of interpolation for the displacement and phase-field variables. Most common is to use linear…

Theories of self-organized active fluid surfaces have emerged as an important class of minimal models for the shape dynamics of biological membranes, cells and tissues. However, due to their inherent geometric nonlinearities and the absence…

软凝聚态物质 · 物理学 2025-07-16 Da Gao , Huayang Sun , Rui Ma , Alexander Mietke