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Blood oxygenation level-dependent (BOLD) functional magnetic resonance imaging (fMRI) is widely used to visualize brain activation regions by detecting hemodynamic responses associated with increased metabolic demand. While alternative MRI…

定量方法 · 定量生物学 2024-09-13 Kyu-Jin Jung , Chuanjiang Cui , Soo-Hyung Lee , Chan-Hee Park , Ji-Won Chun , Dong-Hyun Kim

We present generalized additive latent and mixed models (GALAMMs) for analysis of clustered data with responses and latent variables depending smoothly on observed variables. A scalable maximum likelihood estimation algorithm is proposed,…

统计方法学 · 统计学 2023-03-29 Øystein Sørensen , Anders M. Fjell , Kristine B. Walhovd

Alzheimer's disease (AD) is characterized by a sequence of pathological changes, which are commonly assessed in vivo using MRI and PET. Currently, the most approaches to analyze statistical associations between brain regions rely on Pearson…

神经元与认知 · 定量生物学 2020-03-30 Martin Dyrba , Reza Mohammadi , Michel J. Grothe , Thomas Kirste , Stefan J. Teipel

Thul et al. (2020) called attention to problems that arise when chronometric experiments implementing specific factorial designs are analysed with the generalized additive mixed model (GAMM), using factor smooths to capture trial-to-trial…

统计方法学 · 统计学 2021-11-19 R. Harald Baayen , Matteo Fasiolo , Simon Wood , Yu-Ying Chuang

Random Effects analysis has been introduced into fMRI research in order to generalize findings from the study group to the whole population. Generalizing findings is obviously harder than detecting activation in the study group since in…

应用统计 · 统计学 2013-09-03 Jonathan D. Rosenblatt , Matthijs Vink , Yoav Benjamini

Regression models are popular tools in empirical sciences to infer the influence of a set of variables onto a dependent variable given an experimental dataset. In neuroscience and cognitive psychology, Generalized Linear Models (GLMs)…

应用统计 · 统计学 2020-02-04 Vincent Adam , Alexandre Hyafil

Functional magnetic resonance imaging (fMRI) technology is popularly used in many fields for studying how the brain reacts to mental stimuli. The identification of optimal fMRI experimental designs is crucial for rendering precise…

统计理论 · 数学 2015-10-30 Ching-Shui Cheng , Ming-Hung Kao

Dynamic Random Access Memory (DRAM) is the de-facto choice for main memory devices due to its cost-effectiveness. It offers a larger capacity and higher bandwidth compared to SRAM but is slower than the latter. With each passing generation,…

硬件体系结构 · 计算机科学 2022-01-19 Kaustav Goswami , Hemanta Kumar Mondal , Shirshendu Das , Dip Sankar Banerjee

Inevitable domain and task discrepancies in real-world scenarios can impair the generalization performance of the pre-trained deep models for medical data. Therefore, we audaciously propose that we should build a general-purpose medical AI…

计算机视觉与模式识别 · 计算机科学 2023-03-14 Huahui Yi , Ziyuan Qin , Qicheng Lao , Wei Xu , Zekun Jiang , Dequan Wang , Shaoting Zhang , Kang Li

Large language models (LLMs) have demonstrated that large-scale pretraining enables systems to adapt rapidly to new problems with little supervision in the language domain. This success, however, has not translated as effectively to the…

计算机视觉与模式识别 · 计算机科学 2025-11-04 Pablo Acuaviva , Aram Davtyan , Mariam Hassan , Sebastian Stapf , Ahmad Rahimi , Alexandre Alahi , Paolo Favaro

Generative models based on deep learning have shown significant potential in medical imaging, particularly for modality transformation and multimodal fusion in MRI-based brain imaging. This study introduces GM-LDM, a novel framework that…

图像与视频处理 · 电气工程与系统科学 2025-06-17 Hu Xu , Yang Jingling , Jia Sihan , Bi Yuda , Calhoun Vince

With our ability to record more neurons simultaneously, making sense of these data is a challenge. Functional connectivity is one popular way to study the relationship between multiple neural signals. Correlation-based methods are a set of…

神经元与认知 · 定量生物学 2017-06-09 Tiger W. Lin , Anup Das , Giri P. Krishnan , Maxim Bazhenov , Terrence J. Sejnowski

Functional connectivity refers to the temporal statistical relationship between spatially distinct brain regions and is usually inferred from the time series coherence/correlation in brain activity between regions of interest. In human…

机器学习 · 统计学 2015-03-02 Shaurabh Nandy , Richard M. Golden

Large Language Models (LLMs) have demonstrated strong semantic reasoning across multimodal domains. However, their integration with graph-based models of brain connectivity remains limited. In addition, most existing fMRI analysis methods…

图像与视频处理 · 电气工程与系统科学 2026-05-27 Yasaman Torabi , Parsa Razmara , Hamed Ajorlou , Bardia Baraeinejad

Functional magnetic resonance imaging (fMRI) techniques have contributed significantly to our understanding of brain function. Current methods are based on the analysis of \emph{gradual and continuous} changes in the brain blood oxygenated…

神经元与认知 · 定量生物学 2011-07-25 Enzo Tagliazucchi , Pablo Balenzuela , Daniel Fraiman , Dante R. Chialvo

Functional magnetic resonance imaging or functional MRI (fMRI) is a very popular tool used for differing brain regions by measuring brain activity. It is affected by physiological noise, such as head and brain movement in the scanner from…

统计方法学 · 统计学 2023-10-30 Fangyijie Wang , Michael Salter-Townshend

Motivated by recent work studying massive imaging data in the neuroimaging literature, we propose multivariate varying coefficient models (MVCM) for modeling the relation between multiple functional responses and a set of covariates. We…

统计理论 · 数学 2013-02-19 Hongtu Zhu , Runze Li , Linglong Kong

The field of neuroimaging has truly become data rich, and novel analytical methods capable of gleaning meaningful information from large stores of imaging data are in high demand. Those methods that might also be applicable on the level of…

Irregular sampling and high missingness are intrinsic challenges in modeling time series derived from electronic health records (EHRs),where clinical variables are measured at uneven intervals depending on workflow and intervention timing.…

机器学习 · 计算机科学 2025-09-29 Jeong Eul Kwon , Joo Heung Yoon , Hyo Kyung Lee

Recent research on Vision Language Models (VLMs) suggests that they rely on inherent biases learned during training to respond to questions about visual properties of an image. These biases are exacerbated when VLMs are asked highly…

计算机视觉与模式识别 · 计算机科学 2025-09-11 Saurav Sengupta , Nazanin Moradinasab , Jiebei Liu , Donald E. Brown