相关论文: Automated identification of flagella from videomic…

To swim through a viscous fluid, a flagellated bacterium must overcome the fluid drag on its body by rotating a flagellum or a bundle of multiple flagella. Because the drag increases with the size of bacteria, it is expected theoretically…

The motility of microorganisms is influenced greatly by their hydrodynamic interactions with the fluidic environment they inhabit. We show by direct experimental observation of the bi-flagellated alga Chlamydomonas reinhardtii that fluid…

A growing body of work aims at designing and testing micron-scale synthetic swimmers. One method, inspired by the locomotion of flagellated bacteria, consists of applying a rotating magnetic field to a rigid, helically-shaped, propeller…

A fundamental issue in biology is the nature of evolutionary transitions from unicellular to multicellular organisms. Volvocine algae are models for this transition, as they span from the unicellular biflagellate Chlamydomonas to…

Organelles of optimum size are crucial for proper functioning of a living cell. The cell employs various mechanisms for actively sensing and controlling the size of its organelles. Recently Bauer et al have opened a new research frontier in…

The modeling of the beating of cilia and flagella in fluids is a particularly active field of study, given the biological relevance of these organelles. Various mathematical models have been proposed to represent the nonlinear dynamics of…

Traditional locomotion strategies become ineffective at low Reynolds numbers, where viscous forces predominate over inertial forces. To adapt, microorganisms have evolved specialized structures like cilia and flagella for efficient…

Cellular appendages such as cilia and flagella represent universal tools enabling cells and microbes, among other essential functionalities, to propel themselves in diverse environments. In its planktonic, i.e. freely swimming, state the…

Here we present the first method for tracking each leg of a fruit fly behaving spontaneously upon a trackball, in real time. Legs were tracked with infrared-fluorescent dye invisible to the fly, and compatible with two-photon microscopy and…

Although the auger-like 'swimming' motility of the African trypanosome was described upon its discovery over one hundred years ago, the precise biomechanical and biophysical properties of trypanosome flagellar motion has not been…

We introduce a device developed to perform a 3D tracking of passive or active particles under flow, confined in a medium of hundreds micrometers wide. Micro-objects are placed inside a vertical glass capillary and two mirrors are set behind…

Flagella allow eukaryotic cells to move and pump fluid. We present the first three-dimensional, time-resolved imaging of the flagellar waveform of Chlamydomonas reinhardtii, a model alga found in fresh water. During the power stroke, we…

Papilledema is an ophthalmic neurologic disorder in which increased intracranial pressure leads to swelling of the optic nerves. Undiagnosed papilledema in children may lead to blindness and may be a sign of life-threatening conditions,…

Flagellated microswimmers are ubiquitous in natural habitats. Understanding the hydrodynamic behavior of these cells is of paramount interest, owing to their applications in bio-medical engineering and disease spreading. Since the last two…

Multi-flagellated bacteria utilize the hydrodynamic interaction between their filamentary tails, known as flagella, to swim and change their swimming direction in low Reynolds number flow. This interaction, referred to as bundling and…

The course of a peritrichous bacterium such as E. coli crucially depends on the level of synchronization and self-organization of several rotating flagella. However, the rotation of each flagellum generates counter body movements which in…

Peritrichous bacteria such as Escherichia coli swim in viscous fluids by forming a helical bundle of flagellar filaments. The filaments are spatially distributed around the cell body to which they are connected via a flexible hook. To…

We focus on the biological problem of tracking organelles as they move through cells. In the past, most intracellular movements were recorded manually, however, the results are too incomplete to capture the full complexity of organelle…

Studying animal locomotion improves our understanding of motor control and aids in the treatment of motor impairment. Mice are a premier model of human disease and are the model system of choice for much of basic neuroscience. High frame…

Microorganism motility often takes place within complex, viscoelastic fluid environments, e.g., sperm in cervicovaginal mucus and bacteria in biofilms. In such complex fluids, strains and stresses generated by the microorganism are stored…