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Self-assembly in natural and synthetic molecular systems can create complex aggregates or materials whose properties and functionality rises from their internal structure and molecular arrangement. The key microscopic features that control…

软凝聚态物质 · 物理学 2021-09-03 Alberto Scacchi , Maria Sammalkorpi , Tapio Ala-Nissila

In the current industry, the development of optimized mechanical components able to satisfy the customer requirements evolves quickly. Therefore, companies are asked for efficient solutions to improve their products in terms of stiffness…

计算工程、金融与科学 · 计算机科学 2023-07-31 Rafael Merli , Antolín Martínez-Martínez , Juan José Ródenas , Marc Bosch-Galera , Enrique Nadal

The biological membrane, which compartmentalizes the cell and its organelles, exhibit wide variety of macroscopic shapes of varying morphology and topology. A systematic understanding of the relation of membrane shapes to composition,…

生物物理 · 物理学 2011-09-23 N. Ramakrishnan , P. B. Sunil Kumar , John H. Ipsen

Thin cylindrical tethers are common lipid bilayer membrane structures, arising in situations ranging from micromanipulation experiments on artificial vesicles to the dynamic structure of the Golgi apparatus. We study the shape and formation…

软凝聚态物质 · 物理学 2009-11-07 Thomas R. Powers , Greg Huber , Raymond E. Goldstein

We propose a new statistical model that can reproduce the hierarchical nature of the ubiquitous filamentary structures of molecular clouds. This model is based on the multiplicative random cascade, which is designed to replicate the…

Isotropic pairwise interactions that promote the self assembly of complex particle morphologies have been discovered by inverse design strategies derived from the molecular coarse-graining literature. While such approaches provide an avenue…

统计力学 · 物理学 2019-10-15 Beth A. Lindquist , Ryan B. Jadrich , Michael P. Howard , Thomas M. Truskett

Living cells establish long-range orientational order through collective alignment, giving rise to topological defects whose functional relevance is increasingly recognized in tissue organization and morphogenesis. Engineered topographical…

软凝聚态物质 · 物理学 2025-12-01 Prasoon Awasthi , Aniruddh Murali , Ellen Juel Pørtner , Adam Cohen Simonsen , Francesca Serra

Many types of mammalian cells exert active contractile forces and mechanically deform their elastic substrate, to accomplish biological functions such as cell migration. These substrate deformations provide a mechanism by which cells can…

软凝聚态物质 · 物理学 2022-02-22 Subhaya Bose , Patrick S. Noerr , Ajay Gopinathan , Arvind Gopinath , Kinjal Dasbiswas

There is now growing evidence of the emergence and biological functionality of liquid crystal features, including nematic order and topological defects, in cellular tissues. However, how such features that intrinsically rely on particle…

软凝聚态物质 · 物理学 2019-02-06 Romain Mueller , Julia Yeomans , Amin Doostmohammadi

Nature-occurring structures exhibiting unique topological features such as complex and gradient porosity has been the basis to create new materials and/or structures. Most studies have been focused on complex periodic porous structures but…

A cell is polarised when it has developed a main axis of organisation through the reorganisation of its cytosqueleton and its intracellular organelles. Polarisation can occur spontaneously or be triggered by external signals, like gradients…

偏微分方程分析 · 数学 2013-01-17 Vincent Calvez , Nicolas Meunier , Nicolas Muller , Raphael Voituriez

We use the first Betti number of a complex to characterize the morphological structure of granular samples in mechanical equilibrium. We analyze two-dimensional granular packings after a tapping process by means of both simulations and…

软凝聚态物质 · 物理学 2013-11-07 Sergio Ardanza-Trevijano , Iker Zuriguel , Roberto Arevalo , Diego Maza

A 3D unit cell model containing eight different spherical particles embedded in a homogeneous strain gradient plasticity (SGP) matrix material is presented. The interaction between particles and matrix is controlled by an interface model…

材料科学 · 物理学 2021-06-18 Mohammadali Asgharzadeh , Jonas Faleskog

Bacteria can form a great variety of spatially heterogeneous cell density patterns, ranging from simple concentric rings to dynamical spiral waves appearing in growing colonies. These pattern formation phenomena are important as they…

种群与进化 · 定量生物学 2025-01-17 John S. Chuang , Riccardo Rao , Stanislas Leibler

Topology optimization of modular structures and mechanisms enables balancing the performance of automatically-generated individualized designs, as required by Industry 4.0, with enhanced sustainability by means of component reuse. For…

材料科学 · 物理学 2022-05-25 Marek Tyburec , Martin Doškář , Jan Zeman , Martin Kružík

We present a new framework for the simultaneous optimiziation of both the topology as well as the relative density grading of cellular structures and materials, also known as lattices. Due to manufacturing constraints, the optimization…

计算工程、金融与科学 · 计算机科学 2025-05-27 Jonathan Stollberg , Tarun Gangwar , Oliver Weeger , Dominik Schillinger

Many interesting shapes appearing in the biological world are formed by the onset of mechanical instability. In this work we consider how the build-up of residual stress can cause a solid to buckle. In all past studies a fictitious…

软凝聚态物质 · 物理学 2020-09-15 Pasquale Ciarletta , Michel Destrade , Artur L. Gower , Matteo Taffetani

Systematic expansion schemes in functional approaches require the inclusion of higher order vertices. These vertices are expanded in independent tensor bases with a rapidly increasing number of basis elements. Amongst the related tasks are…

高能物理 - 理论 · 物理学 2025-03-10 Jens Braun , Andreas Geißel , Jan M. Pawlowski , Franz R. Sattler , Nicolas Wink

A constitutive relation between stress and strain relative to a reference state is the basic assumption of elasticity theory. However, in living matter, force generation is governed by motor molecule activity, which does not depend on…

软凝聚态物质 · 物理学 2026-03-17 Nikolas H. Claussen , Fridtjof Brauns , Boris I. Shraiman

Cell-cell adhesion is one the most fundamental mechanisms regulating collective cell migration during tissue development, homeostasis and repair, allowing cell populations to self-organize and eventually form and maintain complex tissue…

细胞行为 · 定量生物学 2022-11-16 Carles Falcó , Ruth E. Baker , José A. Carrillo
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