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The increased availability of medical data has significantly impacted healthcare by enabling the application of machine / deep learning approaches in various instances. However, medical datasets are usually small and scattered across…

Distributed representations of medical concepts have been used to support downstream clinical tasks recently. Electronic Health Records (EHR) capture different aspects of patients' hospital encounters and serve as a rich source for…

计算与语言 · 计算机科学 2020-01-07 Shaika Chowdhury , Chenwei Zhang , Philip S. Yu , Yuan Luo

Clinical diagnosis guidelines aim at specifying the steps that may lead to a diagnosis. Inspired by guidelines, we aim to learn the optimal sequence of actions to perform in order to obtain a correct diagnosis from electronic health…

机器学习 · 计算机科学 2023-11-16 Lillian Muyama , Antoine Neuraz , Adrien Coulet

To overcome the limitations of manual administrative coding in geriatric Cardiovascular Risk Management, this study introduces an automated classification framework leveraging unstructured Electronic Health Records (EHRs). Using a dataset…

The sequential treatment decisions made by physicians to treat chronic diseases are formalized in the statistical literature as dynamic treatment regimes. To date, methods for dynamic treatment regimes have been developed under the…

统计方法学 · 统计学 2022-02-22 Janie Coulombe , Erica E. M. Moodie , Susan M. Shortreed , Christel Renoux

The advent of the Internet era has led to an explosive growth in the Electronic Health Records (EHR) in the past decades. The EHR data can be regarded as a collection of clinical events, including laboratory results, medication records,…

机器学习 · 计算机科学 2019-11-14 Zichang Wang , Haoran Li , Luchen Liu , Haoxian Wu , Ming Zhang

Identifying patient subgroups with different treatment responses is an important task to inform medical recommendations, guidelines, and the design of future clinical trials. Existing approaches for treatment effect estimation primarily…

统计方法学 · 统计学 2025-12-10 Vincent Jeanselme , Chang Ho Yoon , Fabian Falck , Brian Tom , Jessica Barrett

The widespread application of Electronic Health Records (EHR) data in the medical field has led to early successes in disease risk prediction using deep learning methods. These methods typically require extensive data for training due to…

机器学习 · 计算机科学 2024-11-28 Shibo Li , Hengliang Cheng , Weihua Li

Deep Learning (DL) have greatly contributed to bioelectric signals processing, in particular to extract physiological markers. However, the efficacy and applicability of the results proposed in the literature is often constrained to the…

机器学习 · 统计学 2021-10-27 Andrea Bizzego , Giulio Gabrieli , Michelle Jin-Yee Neoh , Gianluca Esposito

Understanding the latent processes from Electronic Medical Records could be a game changer in modern healthcare. However, the processes are complex due to the interaction between at least three dynamic components: the illness, the care and…

机器学习 · 计算机科学 2017-11-23 Phuoc Nguyen , Truyen Tran , Svetha Venkatesh

Researchers are increasingly turning to machine learning (ML) algorithms to investigate causal heterogeneity in randomized experiments. Despite their promise, ML algorithms may fail to accurately ascertain heterogeneous treatment effects…

统计方法学 · 统计学 2024-04-23 Kosuke Imai , Michael Lingzhi Li

An individualized treatment rule (ITR) tailors treatments to a patient's specific characteristics. However, randomized controlled trials (RCTs) are often underpowered to detect the treatment effect heterogeneity needed for reliable ITR…

统计方法学 · 统计学 2026-04-14 Yuan Bian , Donglin Zeng , Hyun-Joon Yang , Leanne M. Williams , Yuanjia Wang

Establishing causality is a fundamental goal in fields like medicine and social sciences. While randomized controlled trials are the gold standard for causal inference, they are not always feasible or ethical. Observational studies can…

统计理论 · 数学 2024-12-03 Andrew Ying

Electronic Health Records (EHRs) provide vital contextual information to radiologists and other physicians when making a diagnosis. Unfortunately, because a given patient's record may contain hundreds of notes and reports, identifying…

There has been significant attention given to developing data-driven methods for tailoring patient care based on individual patient characteristics. Dynamic treatment regimes formalize this through a sequence of decision rules that map…

统计方法学 · 统计学 2022-02-22 Eric J. Rose , Erica E. M. Moodie , Susan Shortreed

Our aging population increasingly suffers from multiple chronic diseases simultaneously, necessitating the comprehensive treatment of these conditions. Finding the optimal set of drugs for a combinatorial set of diseases is a combinatorial…

Personalized decision-making, aiming to derive optimal treatment regimes based on individual characteristics, has recently attracted increasing attention in many fields, such as medicine, social services, and economics. Current literature…

统计方法学 · 统计学 2023-02-28 Jianing Chu , Wenbin Lu , Shu Yang

A treatment regime is a function that maps individual patient information to a recommended treatment, hence explicitly incorporating the heterogeneity in need for treatment across individuals. Patient responses are dichotomous and can be…

机器学习 · 统计学 2016-07-07 Yingfei Wang , Warren Powell

Clinical decision making regarding treatments based on personal characteristics leads to effective health improvements. Machine learning (ML) has been the primary concern of diagnosis support according to comprehensive patient information.…

An optimal dynamic treatment regime (DTR) is a sequence of decision rules aimed at providing the best course of treatments individualized to patients. While conventional DTR estimation uses longitudinal data, such data can also be…

统计方法学 · 统计学 2025-02-06 Larry Dong , Eleanor Pullenayegum , Rodolphe Thiébaut , Olli Saarela