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Schizophrenia (SZ) is a brain disorder leading to detached mind's normally integrated processes. Hence, the exploration of the symptoms in relation to functional connectivity (FC) had great relevance in the field. FC can be investigated on…

神经元与认知 · 定量生物学 2026-04-08 Davide Coluzzi , Giuseppe Baselli

Clinical studies reveal disruptions in brain structural connectivity (SC) and functional connectivity (FC) in neuropsychiatric disorders such as schizophrenia (SZ). Traditional approaches might rely solely on SC due to limited functional…

图像与视频处理 · 电气工程与系统科学 2026-01-27 Badhan Mazumder , Ayush Kanyal , Lei Wu , Vince D. Calhoun , Dong Hye Ye

We investigate assortativity of functional brain networks before, during, and after one-hundred epileptic seizures with different anatomical onset locations. We construct binary functional networks from multi-channel electroencephalographic…

数据分析、统计与概率 · 物理学 2013-09-24 Stephan Bialonski , Klaus Lehnertz

Functional Magnetic Resonance Imaging (fMRI) is commonly utilized to study human brain activity, including abnormal functional properties related to neurodegenerative diseases. This study aims to investigate the differences in the…

神经元与认知 · 定量生物学 2023-05-17 Yongcheng Yao

Personal space (PS) regulation is a key component of effective social engagement. PS varies among individuals and is regulated by brain circuits involving the amygdala and the frontoparietal network. Others have reported that simulated PS…

In spite of years of research, the mechanisms that underlie the development of schizophrenia, as well as its relapse, symptomatology, and treatment, continue to be a mystery. The absence of appropriate analytic tools to deal with the…

计算机视觉与模式识别 · 计算机科学 2022-10-12 Vigneshwaran Shankaran , Bhaskaran V

Schizophrenia is a globally prevalent psychiatric disorder that severely impairs daily life. Schizophrenia is caused by dopamine imbalances in the fronto-striatal pathways of the brain, which influences fine motor control in the cerebellum.…

计算机视觉与模式识别 · 计算机科学 2024-08-14 Rafael Castro , Ishaan Patel , Tarun Patanjali , Priya Iyer

Open problems abound in the theory of complex networks, which has found successful application to diverse fields of science. With the aim of further advancing the understanding of the brain's functional connectivity, we propose to evaluate…

神经元与认知 · 定量生物学 2019-02-20 A. Viol , Fernanda Palhano-Fontes , Heloisa Onias , Draulio B. de Araujo , Philipp Hövel , G. M. Viswanathan

Schizophrenia (SZ) is a mental disorder that typically emerges in late adolescence or early adulthood. It reduces the life expectancy of patients by 15 years. Abnormal behavior, perception of emotions, social relationships, and reality…

Delirium occurs in about 80% cases in the Intensive Care Unit (ICU) and is associated with a longer hospital stay, increased mortality and other related issues. Delirium does not have any biomarker-based diagnosis and is commonly treated…

机器学习 · 计算机科学 2022-05-03 Riddhiman Adib , Md Osman Gani , Sheikh Iqbal Ahamed , Mohammad Adibuzzaman

Basic understanding of biological membranes is of paramount importance as these membranes comprise the very building blocks of life itself. Cells depend in their function on a range of properties of the membrane, which are important for the…

Background: A therapeutic intervention in psychiatry can be viewed as an attempt to influence the brain's large-scale, dynamic network state transitions underlying cognition and behavior. Building on connectome-based graph analysis and…

Coherence is a widely used measure to assess linear relationships between time series. However, it fails to capture nonlinear dependencies. To overcome this limitation, this paper introduces the notion of residual spectral density as a…

统计理论 · 数学 2024-05-21 Yuichi Goto , Xuze Zhang , Benjamin Kedem , Shuo Chen

Face-to-face social interactions are an important aspect of peoples' social lives. A lack of interactions can explain how individuals develop depressive symptoms, but depressive symptoms can also explain how individuals engage in social…

应用统计 · 统计学 2018-11-20 Timon Elmer , Christoph Stadtfeld

Understanding prescription patterns have relied largely on aggregate statistical measures. Evidence of doctor-shopping, inappropriate prescribing, drug diversion and patient seeking prescription drugs across multiple prescribers demand…

应用统计 · 统计学 2018-11-27 Radhakrishnan Nagarajan , Jeffery Talbert

Background: The treatment of depressive episodes is well established, with clearly demonstrated effectiveness of antidepressants and psychotherapies. However, more than one-third of depressed patients do not respond to treatment.…

神经元与认知 · 定量生物学 2024-03-29 Sébastien Dam , Jean-Marie Batail , Gabriel H Robert , Dominique Drapier , Pierre Maurel , Julie Coloigner

Alzheimer's disease (AD) causes alterations of brain network structure and function. The latter consists of connectivity changes between oscillatory processes at different frequency channels. We proposed a multi-layer network approach to…

The physical basis of consciousness is one of the most intriguing open questions that contemporary science aims to solve. By approaching the brain as an interactive information system, complex network theory has greatly contributed to…

Reward processing and derangements thereof, such as drug addiction, involve the coordinated activity of many brain areas. Prior work has identified many behavioral, molecular biological and single neuron changes throughout the…

神经元与认知 · 定量生物学 2012-09-18 Michael Chary

The psychosis spectrum is associated with structural dysconnectivity concentrated in transmodal association cortex. However, understanding of this pathophysiology has been limited by an exclusive focus on the direct connections to a region.…