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For chemical reaction networks described by a master equation, we define energy and entropy on a stochastic trajectory and develop a consistent nonequilibrium thermodynamic description along a single stochastic trajectory of reaction…

统计力学 · 物理学 2009-11-11 Tim Schmiedl , Udo Seifert

We address a fundamental question: under which conditions do the dynamics and thermodynamics of open chemical reaction networks (CRNs), grounded on the notion of idealized chemostats that exchange selected species, emerge from underlying…

统计力学 · 物理学 2026-04-17 Benedikt Remlein , Massimiliano Esposito , Francesco Avanzini

Understanding the emergent behavior of chemical reaction networks (CRNs) is a fundamental aspect of biology and its origin from inanimate matter. A closed CRN monotonically tends to thermal equilibrium, but when it is opened to external…

分子网络 · 定量生物学 2024-05-16 Masanari Shimada , Pegah Behrad , Eric De Giuli

Living systems operate out of equilibrium, continuously consuming energy to sustain organised, functional states. Their emergent behaviour usually relies on a set of interconnected chemical reaction networks (CRNs) driven by external fluxes…

统计力学 · 物理学 2026-02-03 Shiling Liang , Paolo De Los Rios , Daniel Maria Busiello

Stochastic chemical reaction networks (CRNs) are complex systems which combine the features of concurrent transformation of multiple variables in each elementary reaction event, and nonlinear relations between states and their rates of…

化学物理 · 物理学 2017-12-06 Eric Smith , Supriya Krishnamurthy

Power law dynamics is used to describe the stability behavior in metabolic networks such as chemical reaction networks (CRN's). These systems allow multiple steady states within a single stoichiometric class. On the other side thermodynamic…

动力系统 · 数学 2020-07-10 Gunther Friedrich Neumann

A chemical reaction network (CRN) is composed of reactions that can be seen as interactions among entities called species, which exist within the system. Endowed with kinetics, CRN has a corresponding set of ordinary differential equations…

动力系统 · 数学 2021-04-20 Bryan S. Hernandez , Ralph John L. De la Cruz

Materials that are constantly driven out of thermodynamic equilibrium, such as active and living systems, typically violate the Einstein relation. This may arise from active contributions to particle fluctuations which are unrelated to the…

统计力学 · 物理学 2025-01-07 Benjamin Sorkin , Haim Diamant , Gil Ariel , Tomer Markovich

Based on the observation that the thermodynamic equilibrium free energy of an open quantum system in contact with a thermal environment can be understood as the difference between the free energy of the total system and that of the bare…

统计力学 · 物理学 2009-06-01 Michele Campisi , Peter Talkner , Peter Hänggi

We establish a generalized work theorem for stochastic chemical reaction networks (CRNs). By using a compensated Poisson jump process, we identify a martingale structure in a generalized entropy defined relative to an auxiliary backward…

统计力学 · 物理学 2026-01-21 Xiangting Li , Tom Chou

We build a rigorous nonequilibrium thermodynamic description for open chemical reaction networks of elementary reactions. Their dynamics is described by deterministic rate equations satisfying mass action law. Our most general framework…

统计力学 · 物理学 2017-01-13 Riccardo Rao , Massimiliano Esposito

Previous studies have primarily focused on the nonequilibrium thermodynamics of chemical reaction networks (CRNs) occurring in closed systems. In contrast, CRNs in open systems exhibit much richer nonequilibrium phenomena due to sustained…

化学物理 · 物理学 2025-04-14 Xinyu Zhang , Haiyang Jia , Liangrong Peng , Liu Hong

We obtain the Crooks and the Jarzynski non-equilibrium fluctuation relations using a direct quantum-mechanical approach for a finite system that is either isolated or coupled not too strongly to a heat bath. These results were hitherto…

统计力学 · 物理学 2012-07-11 Doron Cohen , Yoseph Imry

Chemical reaction networks (CRNs) are prototypical complex systems because reactions are nonlinear and connected in intricate ways, and they are also essential to understand living systems. Here, I discuss how recent developments in…

统计力学 · 物理学 2020-12-23 Massimiliano Esposito

Starting from the most general formulation of stochastic thermodynamics---i.e. a thermodynamically consistent nonautonomous stochastic dynamics describing systems in contact with several reservoirs---, we define a procedure to identify the…

统计力学 · 物理学 2018-02-07 Riccardo Rao , Massimiliano Esposito

There are only a very few known relations in statistical dynamics that are valid for systems driven arbitrarily far-from-equilibrium. One of these is the fluctuation theorem, which places conditions on the entropy production probability…

统计力学 · 物理学 2009-09-25 Gavin E. Crooks

A theory for non-equilibrium systems is derived from a maximum entropy approach similar in spirit to the equilibrium theory given by Gibbs. Requiring Hamilton's principle of stationary action to be satisfied on average during a trajectory,…

统计力学 · 物理学 2019-02-04 David M. Rogers , Susan B. Rempe

We demonstrate that the Gibbs-Shannon entropy is applicable to non-equilibrium systems of any size and boundary conditions. The change in microscopic entropy can be attributed to the stochastic nature of dynamic processes and to the…

统计力学 · 物理学 2020-10-13 Jianzhong Wu

For classical systems driven out of equilibrium, Crooks derived a relation (the Crooks-Jarzynski relation), whose special cases include a relation (the Crooks relation) equivalent to the Kawasaki non-linear response relation. We derive a…

统计力学 · 物理学 2014-05-26 Hiroshi Matsuoka

Bridging equilibrium and nonequilibrium statistical physics attracts sustained interest. Hallmarks of nonequilibrium systems include a breakdown of detailed balance, and an absence of a priori potential function corresponding to the…

统计力学 · 物理学 2015-04-24 Ying Tang , Ruoshi Yuan , Jianhong Chen , Ping Ao
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