相关论文: Modelling pulsatile blood flow through surgically …
Aspiration thrombectomy is a treatment option for ischemic stroke due to occlusions in large vessels. During the therapy a device is inserted into the vessel and suction is applied. A new one-dimensional model is introduced that is capable…
Predicting the long-term success of endovascular interventions in the clinical management of cerebral aneurysms requires detailed insight into the patient-specific physiological conditions. In this work, we not only propose numerical…
Focused ultrasound stimulated microbubbles have been shown to be capable of inducing blood flow shutdown and necrosis in a range of tissue types in an approach termed antivascular ultrasound or mechanical ablation. In oncology, this…
Acoustic microstreaming has several industrial, therapeutic, and biomedical applications - Acoustic cleaning, micromixing, microfluid transport, hemolysis, sonoporation. The acoustic microstreaming due to the oscillation of ultrasound…
Thrombosis is a common complication following the surgical implantation of blood contacting devices, and is strongly influenced by the phenomenon of near-wall enrichment of platelets. This paper describes a multi-constituent continuum…
Endovascular treatment of cerebral aneurysms aims to achieve functional occlusion and isolation of the aneurysm sac from bloodflow. In clinical practice, treatment success is assessed primarily through digital subtraction angiography (DSA),…
The study of thrombosis is crucial to understand and develop new therapies for diseases like deep vein thrombosis, diabetes related strokes, pulmonary embolism etc. The last two decades have seen an exponential growth in studies related to…
We study a simplified stochastic model for the vascularization of a growing tumor, incorporating the formation of new blood vessels at the tumor periphery as well as their regression in the tumor center. The resulting morphology of the…
Interfacing atomistic-based with continuum-based simulation codes is now required in many multiscale physical and biological systems. We present the first results from coupled atomistic-continuum simulations on 190,000 processors. Platelet…
Some existing models of the atherosclerosis development are discussed and a new improved mathematical model, which takes into account new experimental results about diverse roles of macrophages in atherosclerosis, is proposed. Using technic…
A new mathematical model and numerical approach are proposed for the simulation of fluid and chemical exchanges between a growing capillary network and the surrounding tissue, in the context of tumor-induced angiogenesis. Thanks to proper…
Mathematical models and numerical simulations are widely used in the field of hemodynamics, representing a valuable resource to better understand physiological and pathological processes. The theory behind the phenomenon is closely related…
Microfluidic technology has emerged as a powerful tool for studying complex biological processes with enhanced precision and control. A microfluidic chip was designed to emulate human-like microvascular networks with precise control over…
We present a two dimensional model describing the elastic behaviour of the wall of a curved blood vessel. The wall has a laminate structure consisting of several anisotropic layers of varying thickness and is assumed to be much smaller in…
Subclinical leaflet thrombosis (SLT) is a potentially serious complication of aortic valve replacement with a bioprosthetic valve in which blood clots form on the replacement valve. SLT is associated with increased risk of transient…
In this work, we consider two kinds of model reduction techniques to simulate blood flow through the largest systemic arteries, where a stenosis is located in a peripheral artery i.e. in an artery that is located far away from the heart.…
Blood clots, consisting of red blood cells (RBCs) entrapped within a fibrin network, can cause life-threatening conditions such as stroke and heart attack. The recently developed milli-spinner thrombectomy device presents a promising…
Hemostasis and thrombosis are often thought as two sides of the same clotting mechanism whereas hemostasis is a natural protective mechanism to prevent bleeding and thrombosis is a blood clot abnormally formulated inside a blood vessel,…
Wounds in epithelial tissues compromise their vital role in homeostasis. A rapid and efficient wound healing encompasses different mechanisms, which includes the formation of a contractile actin-myosin cable around its edge, known as the…
In cases when it is desirable to transport medication through blood vessels, especially when dealing with brain cancer being confronted with the narrow arteries in the brain, the blood-brain barrier makes the medical treatment difficult.…