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Recent research into analog computing has introduced new notions of computing real numbers. Huang, Klinge, Lathrop, Li, and Lutz defined a notion of computing real numbers in real-time with chemical reaction networks (CRNs), introducing the…

新兴技术 · 计算机科学 2021-09-08 Willem Fletcher , Titus H. Klinge , James I. Lathrop , Dawn A. Nye , Matthew Rayman

The Turing completeness of continuous chemical reaction networks (CRNs) states that any computable real function can be computed by a continuous CRN on a finite set of molecular species, possibly restricted to elementary reactions, i.e.…

分子网络 · 定量生物学 2022-06-22 Mathieu Hemery , François Fages

We study the model of continuous chemical reaction networks (CRNs), consisting of reactions such as $A+B \to C+D$ that can transform some continuous, nonnegative real-valued quantity (called a *concentration*) of chemical species $A$ and…

新兴技术 · 计算机科学 2024-11-26 Kim Calabrese , David Doty

Chemical reaction networks (CRNs) formally model chemistry in a well-mixed solution. CRNs are widely used to describe information processing occurring in natural cellular regulatory networks, and with upcoming advances in synthetic biology,…

计算复杂性 · 计算机科学 2015-03-20 Ho-Lin Chen , David Doty , David Soloveichik

The concept of input-independent computational time for chemistry-based analog computers was introduced in Anderson-Joshi (2025), where it was shown that arithmetic operations can be computed in a fixed time independent of the input values.…

动力系统 · 数学 2026-04-15 David F. Anderson , Badal Joshi , Tung D. Nguyen

Chemical reaction networks, or CRNs, are known to stably compute semilinear Boolean-valued predicates and functions, provided that all reactions are irreversible. However, this property does not hold for wet-lab implementations, as all…

计算复杂性 · 计算机科学 2026-04-17 Ravi Kini , David Doty

The power of real-time Turing machines using sublinear space is investigated. In contrast to a claim appearing in the literature, such machines can accept non-regular languages, even if working in deterministic mode. While maintaining a…

计算复杂性 · 计算机科学 2019-02-05 Holger Petersen

Chemical reaction networks (CRNs) formally model chemistry in a well-mixed solution. CRNs are widely used to describe information processing occurring in natural cellular regulatory networks, and with upcoming advances in synthetic biology,…

计算复杂性 · 计算机科学 2013-04-17 David Doty

Chemical reaction networks (CRNs) model the behavior of chemical reactions in well-mixed solutions and they can be designed to perform computations. In this tutorial we give an overview of various computational models for CRNs. Moreover, we…

新兴技术 · 计算机科学 2018-11-27 Robert Brijder

The Turing completeness of continuous Chemical Reaction Networks (CRNs) states that any computable real function can be computed by a continuous CRN on a finite set of molecular species, possibly restricted to elementary reactions, i.e.…

定量方法 · 定量生物学 2023-10-24 Mathieu Hemery , François Fages

Coupled chemical interactions in a well-mixed solution are commonly formalized as chemical reaction networks (CRNs). However, despite the widespread use of CRNs in the natural sciences, the range of computational behaviors exhibited by CRNs…

新兴技术 · 计算机科学 2023-04-11 Ho-Lin Chen , David Doty , Wyatt Reeves , David Soloveichik

We propose the chemlambda artificial chemistry, whose behavior strongly suggests that real molecules which embed Interaction Nets patterns and real chemical reactions which resemble Interaction Nets graph rewrites could be a realistic path…

新兴技术 · 计算机科学 2018-11-14 Marius Buliga

Informally, a chemical reaction network is "atomic" if each reaction may be interpreted as the rearrangement of indivisible units of matter. There are several reasonable definitions formalizing this idea. We investigate the computational…

计算复杂性 · 计算机科学 2017-10-03 David Doty , Shaopeng Zhu

The behavior of some stochastic chemical reaction networks is largely unaffected by slight inaccuracies in reaction rates. We formalize the robustness of state probabilities to reaction rate deviations, and describe a formal connection…

计算复杂性 · 计算机科学 2009-01-28 David Soloveichik

We present a novel method for identifying a biochemical reaction network based on multiple sets of estimated reaction rates in the corresponding reaction rate equations arriving from various (possibly different) experiments. The current…

应用统计 · 统计学 2008-10-06 Gheorghe Craciun , Casian Pantea , Grzegorz A. Rempala

We review in a unified way results for two types of stochastic chemical reaction systems for which moments can be effectively computed: feedforward networks and complex-balanced networks.

最优化与控制 · 数学 2016-12-08 Eduardo D. Sontag

Reaction systems are a formal model that has been introduced to investigate the interactive behaviors of biochemical reactions. Based on the formal framework of reaction systems, we propose new computing models called reaction automata that…

形式语言与自动机理论 · 计算机科学 2011-11-29 Fumiya Okubo , Satoshi Kobayashi , Takashi Yokomori

The automated inference of physically interpretable (bio)chemical reaction network models from measured experimental data is a challenging problem whose solution has significant commercial and academic ramifications. It is demonstrated,…

神经与进化计算 · 计算机科学 2014-12-22 Dominic P. Searson , Mark J. Willis , Allen Wright

In the theory of algorithmic randomness, one of the central notions is that of computable randomness. An infinite binary sequence X is computably random if no recursive martingale (strategy) can win an infinite amount of money by betting on…

计算机科学与博弈论 · 计算机科学 2015-05-18 Laurent Bienvenu , Frank Stephan , Jason Teutsch

Discrete chemical reaction networks formalize the interactions of molecular species in a well-mixed solution as stochastic events. Given their basic mathematical and physical role, the computational power of chemical reaction networks has…

计算复杂性 · 计算机科学 2023-07-07 Austin Luchsinger , David Doty , David Soloveichik
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