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In this work we focus on examination and comparison of whole-brain functional connectivity patterns measured with fMRI across experimental conditions. Direct examination and comparison of condition-specific matrices is challenging due to…

应用统计 · 统计学 2013-01-02 Svetlana V. Shinkareva , Vladimir Gudkov , Jing Wang

The MRI-derived brain network serves as a pivotal instrument in elucidating both the structural and functional aspects of the brain, encompassing the ramifications of diseases and developmental processes. However, prevailing methodologies,…

机器学习 · 计算机科学 2024-05-24 Haoteng Tang , Guodong Liu , Siyuan Dai , Kai Ye , Kun Zhao , Wenlu Wang , Carl Yang , Lifang He , Alex Leow , Paul Thompson , Heng Huang , Liang Zhan

Dynamic functional connectivity is an effective measure for the brain's responses to continuous stimuli. We propose an inferential method to detect the dynamic changes of brain networks based on time-varying graphical models. Whereas most…

应用统计 · 统计学 2020-06-23 Dingjue Ji , Junwei Lu , Yiliang Zhang , Hongyu Zhao , Siyuan Gao

Dynamic networks have been increasingly used to characterize brain connectivity that varies during resting and task states. In such characterizations, a connectivity network is typically measured at each time point for a subject over a…

统计方法学 · 统计学 2023-03-23 Maoyu Zhang , Biao Cai , Wenlin Dai , Dehan Kong , Hongyu Zhao , Jingfei Zhang

Anatomic connections between brain areas affect information flow between neuronal circuits and the synchronization of neuronal activity. However, such structural connectivity does not coincide with effective connectivity, related to the…

神经元与认知 · 定量生物学 2015-06-03 Demian Battaglia , Annette Witt , Fred Wolf , Theo Geisel

In this paper, we study the dynamics of epidemic processes taking place in adaptive networks of arbitrary topology. We focus our study on the adaptive susceptible-infected-susceptible (ASIS) model, where healthy individuals are allowed to…

社会与信息网络 · 计算机科学 2016-06-29 Masaki Ogura , Victor M. Preciado

Brain connectivity analysis is now at the foreground of neuroscience research. A connectivity network is characterized by a graph, where nodes represent neural elements such as neurons and brain regions, and links represent statistical…

统计方法学 · 统计学 2015-11-04 Yin Xia , Lexin Li

The main result of this thesis is the development of a novel connectivity estimation method, called Total Spiking Probability Edges (TSPE). Based on cross-correlation and edge filtering at different time scales this method is proposed and…

信号处理 · 电气工程与系统科学 2020-05-15 Stefano De Blasi

Functional Magnetic Resonance Imaging (fMRI) is an imaging technique widely used to study human brain activity. fMRI signals in areas across the brain transiently synchronise and desynchronise their activity in a highly structured manner,…

机器学习 · 计算机科学 2025-08-12 Yiran Huang , Amirhossein Nouranizadeh , Christine Ahrends , Mengjia Xu

Estimating causal networks from biological data is a critical step in systems biology. When evaluating the inferred network, assessing the networks based on their intervention effects is particularly important for downstream probabilistic…

分子网络 · 定量生物学 2025-11-18 Noriaki Sato , Marco Scutari , Shuichi Kawano , Rui Yamaguchi , Seiya Imoto

The representation of the flow of information between neurons in the brain based on their activity is termed the causal functional connectome. Such representation incorporates the dynamic nature of neuronal activity and causal interactions…

神经元与认知 · 定量生物学 2022-11-16 Rahul Biswas , Eli Shlizerman

Plasticity is one of the most important properties of the nervous system, which enables animals to adjust their behavior to the ever-changing external environment. Changes in synaptic efficacy between neurons constitute one of the major…

神经元与认知 · 定量生物学 2018-01-23 Taishi Iwasaki , Hideitsu Hino , Masami Tatsuno , Shotaro Akaho , Noboru Murata

Estimating causal interactions in the brain from functional magnetic resonance imaging (fMRI) data remains a challenging task. Multiple studies have demonstrated that all current approaches to determine direction of connectivity perform…

神经元与认知 · 定量生物学 2019-05-31 Natalia Bielczyk , Alberto Llera , Jan Buitelaar , Jeffrey Glennon , Christian Beckmann

Functional connectivity (FC) analysis of resting-state fMRI data provides a framework for characterizing brain networks and their association with participant-level covariates. Due to the high dimensionality of neuroimaging data, standard…

统计方法学 · 统计学 2025-08-18 Wei Zhao , Brian J. Reich , Emily C. Hector

Intrinsic brain activity is characterized by highly structured co-activations between different regions, whose origin is still under debate. In this paper, we address the question whether it is possible to unveil how the underlying…

Brain networks from functional MRI have advanced our understanding of cortical activity and its disruption in neurodegenerative disorders. Recent work has increasingly focused on dynamic (time-varying) brain networks that capture both…

神经元与认知 · 定量生物学 2026-04-14 Nicolas Rubido , Venia Batziou , Marwan Fuad , Vesna Vuksanovic

Functional connectivity refers to the temporal statistical relationship between spatially distinct brain regions and is usually inferred from the time series coherence/correlation in brain activity between regions of interest. In human…

机器学习 · 统计学 2015-03-02 Shaurabh Nandy , Richard M. Golden

Cellular neural circuit and networks consisting of interconnected neurons and glia are ulti- mately responsible for the information processing associated with information processing in the brain. While there are major efforts aimed at…

神经元与认知 · 定量生物学 2015-05-18 Marius Buibas , Gabriel A. Silva

Resting-state brain functional connectivity quantifies the synchrony between activity patterns of different brain regions. In functional magnetic resonance imaging (fMRI), each region comprises a set of spatially contiguous voxels at which…

统计方法学 · 统计学 2025-11-07 Ruobin Liu , Chao Zhang , Chau Tran , Sophie Achard , Wendy Meiring , Alexander Petersen

Functional Connectivity between brain regions is known to be altered in Alzheimer's disease, and promises to be a biomarker for early diagnosis of the disease. While several approaches for functional connectivity obtain an un-directed…

神经元与认知 · 定量生物学 2024-02-21 Rahul Biswas , SuryaNarayana Sripada