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Segmentation and quantification of white matter hyperintensities (WMHs) are of great importance in studying and understanding various neurological and geriatric disorders. Although automatic methods have been proposed for WMH segmentation…

计算机视觉与模式识别 · 计算机科学 2018-03-20 Dakai Jin , Ziyue Xu , Adam P. Harrison , Daniel J. Mollura

Automated segmentation of white matter hyperintensities (WMHs) is an essential step in neuroimaging analysis of Magnetic Resonance Imaging (MRI). Fluid Attenuated Inversion Recovery (FLAIR-weighted) is an MRI contrast that is particularly…

图像与视频处理 · 电气工程与系统科学 2023-05-15 Martin Soria Røvang , Per Selnes , Bradley John MacIntosh , Inge Rasmus Groote , Lene Paalhaugen , Sudre Carole , Tormod Fladby , Atle Bjørnerud

White Matter Hyperintensities (WMH) are areas of the brain that have higher intensity than other normal brain regions on Magnetic Resonance Imaging (MRI) scans. WMH is often associated with small vessel disease in the brain, making early…

图像与视频处理 · 电气工程与系统科学 2023-05-09 Muhammad Noor Dwi Eldianto , Muhammad Febrian Rachmadi , Wisnu Jatmiko

The accurate assessment of White matter hyperintensities (WMH) burden is of crucial importance for epidemiological studies to determine association between WMHs, cognitive and clinical data. The manual delineation of WMHs is tedious, costly…

组织与器官 · 定量生物学 2018-01-03 R. Guerrero , C. Qin , O. Oktay , C. Bowles , L. Chen , R. Joules , R. Wolz , M. C. Valdes-Hernandez , D. A. Dickie , J. Wardlaw , D. Rueckert

White matter hyperintensities (WMH) are radiological markers of small vessel disease and neurodegeneration, whose accurate segmentation and spatial localization are crucial for diagnosis and monitoring. While multimodal MRI offers…

图像与视频处理 · 电气工程与系统科学 2025-06-30 Julia Machnio , Sebastian Nørgaard Llambias , Mads Nielsen , Mostafa Mehdipour Ghazi

White matter hyperintensity (WMH) is commonly found in elder individuals and appears to be associated with brain diseases. U-net is a convolutional network that has been widely used for biomedical image segmentation. Recently, U-net has…

计算机视觉与模式识别 · 计算机科学 2018-07-30 Yue Zhang , Wanli Chen , Yifan Chen , Xiaoying Tang

The relationship between cognition and white matter hyperintensities (WMH) volumes often depends on the accuracy of the lesion segmentation algorithm used. As such, accurate detection and quantification of WMH is of great interest. Here, we…

图像与视频处理 · 电气工程与系统科学 2020-12-25 Lavanya Umapathy , Gloria Guzman Perez-Carillo , Blair Winegar , Srinivasan Vedantham , Maria Altbach , Ali Bilgin

Segmentation of both large and small white matter hyperintensities/lesions in brain MR images is a challenging task which has drawn much attention in recent years. We propose a multi-scale aggregation model framework to deal with…

计算机视觉与模式识别 · 计算机科学 2019-02-28 Hongwei Li , Jianguo Zhang , Mark Muehlau , Jan Kirschke , Bjoern Menze

White matter hyperintensities (WMH) are key imaging markers in cognitive aging, Alzheimer's disease (AD), and related dementias. Although automated methods for WMH segmentation have advanced, most provide only global lesion load and…

计算机视觉与模式识别 · 计算机科学 2025-11-19 Julia Machnio , Mads Nielsen , Mostafa Mehdipour Ghazi

In this paper, we develop a two-stage neural network solution for the challenging task of white-matter lesion segmentation. To cope with the vast vari- ability in lesion sizes, we sample brain MR scans with patches at three differ- ent…

计算机视觉与模式识别 · 计算机科学 2018-07-26 Zhewei Wang , Charles D. Smith , Jundong Liu

White Matter Hyperintensities (WMH) are the most common manifestation of cerebral small vessel disease (cSVD) on the brain MRI. Accurate WMH segmentation algorithms are important to determine cSVD burden and its clinical consequences. Most…

图像与视频处理 · 电气工程与系统科学 2020-12-23 Zicong Zhang , Kimerly Powell , Changchang Yin , Shilei Cao , Dani Gonzalez , Yousef Hannawi , Ping Zhang

Brain atrophy and white matter hyperintensity (WMH) are critical neuroimaging features for ascertaining brain injury in cerebrovascular disease and multiple sclerosis. Automated segmentation and quantification is desirable but existing…

White matter hyperintensity (WMH) remains the top imaging biomarker for neurodegenerative diseases. Robust and accurate segmentation of WMH holds paramount significance for neuroimaging studies. The growing shift from 3T to 7T MRI…

图像与视频处理 · 电气工程与系统科学 2024-02-21 Jinghang Li , Tales Santini , Yuanzhe Huang , Joseph M. Mettenburg , Tamer S. Ibrahim , Howard J. Aizenstein , Minjie Wu

Multiple sclerosis (MS) is a demyelinating disease that affects more than 2 million people worldwide. The most used imaging technique to help in its diagnosis and follow-up is magnetic resonance imaging (MRI). Fluid Attenuated Inversion…

计算机视觉与模式识别 · 计算机科学 2018-07-26 Paulo G. L. Freire , Ricardo J. Ferrari

White Matter Hyperintensity (WMH) is an imaging feature related to various diseases such as dementia and stroke. Accurately segmenting WMH using computer technology is crucial for early disease diagnosis. However, this task remains…

图像与视频处理 · 电气工程与系统科学 2025-07-08 Changlu Guo

Segmenting vascular pathologies such as white matter lesions in Brain magnetic resonance images (MRIs) require acquisition of multiple sequences such as T1-weighted (T1-w) --on which lesions appear hypointense-- and fluid attenuated…

计算机视觉与模式识别 · 计算机科学 2018-08-21 Mauricio Orbes-Arteaga , M. Jorge Cardoso , Lauge Sørensen , Marc Modat , Sébastien Ourselin , Mads Nielsen , Akshay Pai

Deep learning (DL) methods for white matter lesion (WML) segmentation in MRI suffer a reduction in performance when applied on data from a scanner or centre that is out-of-distribution (OOD) from the training data. This is critical for…

图像与视频处理 · 电气工程与系统科学 2023-07-11 Abdollah Ghazvanchahi , Pejman Jahbedar Maralani , Alan R. Moody , April Khademi

Purpose: Multiple sclerosis (MS) diagnosis requires accurate assessment of white matter hyperintensities (WMH) and ventricular changes on brain MRI. Current methods treat these structures independently, struggle to differentiate normal from…

图像与视频处理 · 电气工程与系统科学 2026-02-20 Mahdi Bashiri Bawil , Mousa Shamsi , Abolhassan Shakeri Bavil

White matter hyperintensities (WMH) are a hallmark of cerebrovascular disease and multiple sclerosis. Automated WMH segmentation methods enable quantitative analysis via estimation of total lesion load, spatial distribution of lesions, and…

图像与视频处理 · 电气工程与系统科学 2024-03-22 Xiaoling Hu , Annabel Sorby-Adams , Frederik Barkhof , W Taylor Kimberly , Oula Puonti , Juan Eugenio Iglesias
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