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Bacteria can form a great variety of spatially heterogeneous cell density patterns, ranging from simple concentric rings to dynamical spiral waves appearing in growing colonies. These pattern formation phenomena are important as they…

种群与进化 · 定量生物学 2025-01-17 John S. Chuang , Riccardo Rao , Stanislas Leibler

Swarm stability is concerned for descriptor compartmental networks with linear time-invariant protocol. Compartmental network is a specific type of dynamical multi-agent system. Necessary and sufficient conditions for both consensus and…

系统与控制 · 计算机科学 2015-01-13 Ning Cai , M. Junaid Khan

Cooperative mutualism is a major force driving evolution and sustaining ecosystems. Although the importance of spatial degrees of freedom and number fluctuations is well-known, their effects on mutualism are not fully understood. With range…

种群与进化 · 定量生物学 2015-05-27 K. S. Korolev , David R. Nelson

Standard models of population dynamics focus on the the interaction, survival, and extinction of the competing species individually. Real ecological systems, however, are characterized by an abundance of species (or strategies, in the…

种群与进化 · 定量生物学 2014-05-27 Alexander Dobrinevski , Mikko Alava , Tobias Reichenbach , Erwin Frey

Compartmental models based on tracer mass balance are extensively used in clinical and pre-clinical nuclear medicine in order to obtain quantitative information on tracer metabolism in the biological tissue. This paper is the first of a…

定量方法 · 定量生物学 2018-08-21 Fabrice Delbary , Sara Garbarino , Valentina Vivaldi

Variable selection is an important statistical problem. This problem becomes more challenging when the candidate predictors are of mixed type (e.g. continuous and binary) and impact the response variable in nonlinear and/or non-additive…

统计方法学 · 统计学 2021-12-30 Chuji Luo , Michael J. Daniels

In this paper, we extend a model of host-parasite co-evolution to incorporate the semi-conservative nature of DNA replication for both the host and the parasite. We find that the optimal mutation rate for the semi-conservative and…

种群与进化 · 定量生物学 2009-11-10 Yisroel Brumer , Eugene I. Shakhnovich

By generalizing a class of models recently introduced to account for protracted transients in biological systems, we identify a novel mechanism for hyperuniformity. In this model, competition of particles over a shared resource guides the…

统计力学 · 物理学 2025-12-11 Tal Agranov , Natan Wiegenfeld , Omer Karin , Benjamin D. Simons

We study the large-time behavior of an ensemble of entities obeying replicator-like stochastic dynamics with mean-field interactions as a model for a primordial ecology. We prove the propagation-of-chaos property and establish conditions…

The spread of infectious disease and the evolution of antigenically distinct strains are often modeled separately, despite strong feedbacks mediated by host immune memory and heterogeneous contacts. To tackle this challenging problem, we…

种群与进化 · 定量生物学 2026-04-01 Davide Zanchetta , Vittoria Bettio , Sandro Azaele , Manlio De Domenico

With the attention mechanism, transformers achieve significant empirical successes. Despite the intuitive understanding that transformers perform relational inference over long sequences to produce desirable representations, we lack a…

机器学习 · 计算机科学 2024-04-02 Yufeng Zhang , Boyi Liu , Qi Cai , Lingxiao Wang , Zhaoran Wang

As pathogens spread in a population of hosts, immunity is built up and the pool of susceptible individuals is depleted. This generates selective pressure, to which many human RNA viruses, such as influenza virus or SARS-CoV-2, respond with…

种群与进化 · 定量生物学 2024-08-29 Pierre Barrat-Charlaix , Richard A. Neher

We study the population dynamics of lytic viruses which replicate slowly in dividing host cells within an organism or cell culture, and find a range of viral replication rates that allows viruses to persist, avoiding extinction of host…

种群与进化 · 定量生物学 2013-05-29 Jingshan Zhang , Eugene I. Shakhnovich

We study the competition of two spreading entities, for example innovations, in complex contagion processes in complex networks. We develop an analytical framework and examine the role of dual users, i.e. agents using both technologies.…

物理与社会 · 物理学 2018-11-30 Byungjoon Min , Maxi San Miguel

In this paper we present a network model to study the impact of spatial distribution of constituents, coupling between them and diffusive processes in the context of biological situations. The model is in terms of network of mobile elements…

分子网络 · 定量生物学 2007-05-23 Kanchan Thadani , Ashutosh

During recent years, the study of long transients has been expanded in ecological theory to account for shifts in long-term behavior of ecological systems. These long transients may lead to regime shifts between alternative states that…

种群与进化 · 定量生物学 2023-05-02 Jorge Arroyo-Esquivel , Alan Hastings , Marissa L Baskett

Metagenomics has revealed hundreds of bacterial species in almost all microbiota. In a few well-studied cases, bacterial communities have been observed to coordinate their metabolic fluxes. In principle, bacteria can divide tasks to reap…

种群与进化 · 定量生物学 2016-04-12 Thibaud Taillefumier , Anna Posfai , Yigal Meir , Ned S. Wingreen

Artificial ecosystems provide an additional experimental tool to support laboratory work, field work, and theoretical development in competitive exclusion research. A novel application of a spatiotemporal agent based model is presented…

种群与进化 · 定量生物学 2023-06-01 John C. Stevenson

Membrane pores are implicated in several critical functions, including cell fusion and the transport of signaling molecules for intercellular communication. However, these structural features are often difficult to probe directly. Droplet…

Cooperation is ubiquitous across all levels of biological systems ranging from microbial communities to human societies. It, however, seemingly contradicts the evolutionary theory, since cooperators are exploited by free-riders and thus are…

种群与进化 · 定量生物学 2019-09-23 Yunming Xiao , Bin Wu
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