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Brownian dynamics (BD) simulations are used to study the translocation dynamics of a coarse-grained polymer through a cylindrical nanopore. We consider the case of short polymers, with a polymer length, N, in the range N=21-61. The rate of…

软凝聚态物质 · 物理学 2015-06-18 James M. Polson , Taylor Dunn

Monte Carlo (MC) simulations are used to study the dynamics of polymer translocation through a nanopore in the limit where the translocation rate is sufficiently slow that the polymer maintains a state of conformational quasi-equilibrium.…

软凝聚态物质 · 物理学 2015-06-12 James M. Polson , Anthony C. M. McCaffrey

Most of the theoretical models describing the translocation of a polymer chain through a nanopore use the hypothesis that the polymer is always relaxed during the complete process. In other words, models generally assume that the…

生物大分子 · 定量生物学 2009-11-13 Michel G. Gauthier , Gary W. Slater

We revisit the Fokker-Planck based theory of driven polymer translocation through a narrow nanopore. A bead-spring model of a uniformly charged polyelectrolyte chain translocating through a semi-implicit model of a nanopore embedded in a…

软凝聚态物质 · 物理学 2025-12-02 Bhavesh R. Sarode , Harshwardhan H. Katkar

We study the driven translocation of a semi-flexible polymer through a nanopore by means of a modified version of the iso-flux tension propagation theory (IFTP), and extensive molecular dynamics (MD) simulations. We show that in contrast to…

软凝聚态物质 · 物理学 2016-12-28 Jalal Sarabadani , Timo Ikonen , Harri Mökkönen , Tapio Ala-Nissila , Spencer Carson , Meni Wanunu

The translocation time of a polymer chain through an interaction energy gradient nanopore was studied by Monte Carlo simulations and the Fokker-Planck equation with double-absorbing boundary conditions. Both the simulation and calculation…

软凝聚态物质 · 物理学 2017-01-04 Meng-Bo Luo , Shuang Zhang , Fan Wu , Li-Zhen Sun

We suggest a theoretical description of the force-induced translocation dynamics of a polymer chain through a nanopore. Our consideration is based on the tensile (Pincus) blob picture of a pulled chain and the notion of propagating front of…

软凝聚态物质 · 物理学 2012-04-17 J. L. A. Dubbeldam , V. G. Rostiashvili , A. Milchev , T. A. Vilgis

We consider the dynamics of pore-driven polymer translocation through a nanopore to semi-infinite space when the chain is initially confined and equilibrated in a narrow channel. To this end, we use Langevin dynamics (LD) simulations and…

软凝聚态物质 · 物理学 2025-03-11 Soheila Emamyari , Jalal Sarabadani , Ralf Metzler , Tapio Ala-Nissila

We investigate the dynamics of pore-driven polymer translocation by theoretical analysis and molecular dynamics (MD) simulations. Using the tension propagation theory within the constant flux approximation we derive an explicit equation of…

软凝聚态物质 · 物理学 2015-06-23 Jalal Sarabadani , Timo Ikonen , Tapio Ala-Nissila

We investigate the dynamics of polymer translocation through a nanopore using two-dimensional Langevin dynamics simulations. In the absence of external driving force, we consider a polymer which is initially placed in the middle of the pore…

软凝聚态物质 · 物理学 2007-05-23 Ilkka Huopaniemi , Kaifu Luo , Tapio Ala-Nissila , See-Chen Ying

Polymer translocation through a nano-pore in a thin membrane is studied using a coarse-grained bead-spring model and Langevin dynamics simulation with a particular emphasis to explore out of equilibrium characteristics of the translocating…

软凝聚态物质 · 物理学 2015-05-14 Aniket Bhattacharya , Kurt Binder

We consider the translocation dynamics of a polymer chain forced through a nanopore by an external force on its head monomer on the trans side. For a proper theoretical treatment we generalize the iso-flux tension propagation (IFTP) theory…

软凝聚态物质 · 物理学 2018-02-14 Jalal Sarabadani , Bappa Ghosh , Srabanti Chaudhury , Tapio Ala-Nissila

We study translocation of semiflexible polymers driven by force $f_d$ inside a nanometer-scale pore using our three-dimensional Langevin dynamics model. We show that the translocation time $\tau$ increases with increasing bending rigidity…

生物物理 · 物理学 2018-06-27 Pauli M. Suhonen , Riku P. Linna

Polymer translocation has long been a topic of interest in the field of biological physics given its relevance in both biological (protein and DNA/RNA translocation through nuclear and cell membranes) and technological processes (nanopore…

软凝聚态物质 · 物理学 2023-09-11 Alejandro Sainz-Agost , Fernando Falo , Alessandro Fiasconaro

We study the translocation dynamics of a polymer chain threaded through a nanopore by an external force. By means of diverse methods (scaling arguments, fractional calculus and Monte Carlo simulation) we show that the relevant dynamic…

统计力学 · 物理学 2007-07-29 J. L. A. Dubbeldam , A. Milchev , V. G. Rostiashvili , T. A. Vilgis

We investigate the dynamics of polymer translocation through a nanopore under an externally applied field using the 2D fluctuating bond model with single-segment Monte Carlo moves. We concentrate on the influence of the field strength $E$,…

软凝聚态物质 · 物理学 2011-08-26 Kaifu Luo , Ilkka Huopaniemi , Tapio Ala-Nissila , See-Chen Ying

We employ 3D Langevin Dynamics simulations to study the dynamics of polymer chains translocating through a nanopore in presence of asymmetric solvent conditions. Initially a large fraction ($>$ 50%) of the chain is placed at the…

软凝聚态物质 · 物理学 2010-06-09 Christopher Lorscher , Tapio Ala-Nissila , Aniket Bhattacharya

We present a theoretical description of the dynamics of a semi-flexible polymer being pulled through a nanopore by an external force acting at the pore. Our theory is based on the tensile blob picture of Pincus in which the front of the…

统计力学 · 物理学 2015-09-16 Pui-Man Lam , Yi Zhen

The impact of thermal fluctuations on the translocation dynamics of a polymer chain driven through a narrow pore has been investigated theoretically and by means of extensive Molecular-Dynamics (MD) simulation. The theoretical consideration…

软凝聚态物质 · 物理学 2015-06-12 J. L. A. Dubbeldam , V. G. Rostiashvili , A. Milchev , T. A. Vilgis

We investigate polymer translocation through a nanopore under a pulling force using Langevin dynamics simulations. We concentrate on the influence of the chain length $N$ and the pulling force $F$ on the translocation time $\tau$. The…

软凝聚态物质 · 物理学 2007-06-27 Ilkka Huopaniemi , Kaifu luo , Tapio Ala-Nissila , See-Chen Ying
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