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Rare variants are hypothesized to be largely responsible for heritability and susceptibility to disease in humans. So rare variants association studies hold promise for understanding disease. Conversely though, the rareness of the variants…

统计方法学 · 统计学 2021-12-06 Lorenzo Masoero , Joshua Schraiber , Tamara Broderick

Researchers often turn to block randomization to increase the precision of their inference or due to practical considerations, such as in multisite trials. However, if the number of treatments under consideration is large it might not be…

统计方法学 · 统计学 2025-08-26 Taehyeon Koo , Nicole E. Pashley

In this paper, we consider nonparametric multidimensional finite mixture models and we are interested in the semiparametric estimation of the population weights. Here, the i.i.d. observations are assumed to have at least three components…

统计理论 · 数学 2017-12-14 Elisabeth Gassiat , Judith Rousseau , Elodie Vernet

We consider the problem of integrating a small probability sample (ps) and a non-probability sample (nps). By definition, for the nps, there are no survey weights, but for the ps, there are survey weights. The key issue is that the nps,…

统计方法学 · 统计学 2023-05-17 Balgobin Nandram , JNK Rao

Stochastic models of sequential mutation acquisition are widely used to quantify cancer and bacterial evolution. Across manifold scenarios, recurrent research questions are: how many cells are there with $n$ alterations, and how long will…

种群与进化 · 定量生物学 2023-07-07 Michael D. Nicholson , David Cheek , Tibor Antal

We characterize the identified sets of a wide range of stochastic choice models, including random utility, various models of boundedly-rational behavior, and dynamic discrete choice. In each of these settings, we show two distributions over…

理论经济学 · 经济学 2026-02-24 Peter Caradonna , Christopher Turansick

Complex system design problems, such as those involved in aerospace engineering, require the use of numerically costly simulation codes in order to predict the performance of the system to be designed. In this context, these codes are often…

最优化与控制 · 数学 2024-02-14 Loic Brevault , Mathieu Balesdent

We develop a model-based empirical Bayes approach to variable selection problems in which the number of predictors is very large, possibly much larger than the number of responses (the so-called 'large p, small n' problem). We consider the…

统计方法学 · 统计学 2015-10-14 Haim Y. Bar , James G. Booth , Martin T. Wells

We describe a general strategy for sampling configurations from a given (Gibbs-Boltzmann or other) distribution. It is {\it not} based on the Metropolis concept of establishing a Markov process whose stationary state is the wanted…

统计力学 · 物理学 2007-05-23 P. Grassberger , W. Nadler

A multi-type neutral Cannings population model with mutation and fixed subpopulation sizes is analyzed. Under appropriate conditions, as all subpopulation sizes tend to infinity, the ancestral process, properly time-scaled, converges to a…

概率论 · 数学 2023-04-13 Martin Möhle

Most population models assume that individuals within a given population are identical, that is, the fundamental role of variation is ignored. Inhomogeneous models of populations and communities allow for birth and death rates to vary among…

种群与进化 · 定量生物学 2007-05-23 Georgy P. Karev

Products manufactured from the same batch or utilized in the same region often exhibit correlated lifetime observations due to the latent heterogeneity caused by the influence of shared but unobserved covariates. The unavailable…

统计方法学 · 统计学 2021-07-15 Xuxue Sun , Mingyang Li

This paper introduces a variational formulation of natural selection, paying special attention to the nature of "things" and the way that different "kinds" of "things" are individuated from - and influence - each other. We use the Bayesian…

种群与进化 · 定量生物学 2023-07-05 Karl Friston , Daniel Ari Friedman , Axel Constant , V. Bleu Knight , Thomas Parr , John O. Campbell

Survival regression is widely used to model time-to-events data, to explore how covariates may influence the occurrence of events. Modern datasets often encompass a vast number of covariates across many subjects, with only a subset of the…

统计方法学 · 统计学 2024-09-18 Abhishek Mandal , Abhisek Chakraborty

We study the problem of approximately transforming a sample from a source statistical model to a sample from a target statistical model without knowing the parameters of the source model, and construct several computationally efficient such…

统计理论 · 数学 2024-09-19 Mengqi Lou , Guy Bresler , Ashwin Pananjady

Machine learning methods for computational imaging require uncertainty estimation to be reliable in real settings. While Bayesian models offer a computationally tractable way of recovering uncertainty, they need large data volumes to be…

机器学习 · 计算机科学 2020-08-24 Francesco Tonolini , Jack Radford , Alex Turpin , Daniele Faccio , Roderick Murray-Smith

Bootstrap methods are increasingly accepted as one of the common approaches in constructing confidence intervals in bibliometric studies. Typical bootstrap methods assume that the statistical population is infinite. When the statistical…

应用统计 · 统计学 2018-04-17 Tina Nane , Kasper Kooijman

In conventional randomized controlled trials, adjustment for baseline values of covariates known to be at least moderately associated with the outcome increases the power of the trial. Recent work has shown particular benefit for more…

统计方法学 · 统计学 2023-11-27 James Willard , Shirin Golchi , Erica EM Moodie

Analysing age-specific mortality, fertility, and migration patterns is a crucial task in demography with significant policy relevance. In practice, such analysis is challenging when studying a large number of subpopulations, due to small…

应用统计 · 统计学 2025-05-29 Gregor Zens

Following the Bayesian communication learning paradigm, we propose a finite population learning concept to capture the level of information aggregation in any given network, where agents are allowed to communicate with neighbors repeatedly…

社会与信息网络 · 计算机科学 2012-12-13 Jianqing Fan , Xin Tong , Yao Zeng