相关论文: Fluorescence decay data analysis correcting for de…
Fluorescence-detected Fourier transform (FT) spectroscopy is a technique in which the relative paths of an optical interferometer are controlled to excite a material sample, and the ensuing fluorescence is detected as a function of the…
Super-resolution Structured Illumination Microscopy (SR-SIM) enables fluorescence microscopy beyond the diffraction limit at high frame rates. Compared to other super-resolution microscopy techniques, the low photon fluence used in SR-SIM…
Detector characterization and instrumentation testing are often performed at cyclotron and synchrotron facilities, many of which were originally developed for medical applications in cancer therapy. For particle physics experiments…
Single-photon detection and photon counting play a central role in a large number of quantum communication and computation protocols. While the efficiency of state-of-the-art photo-detectors is well below the desired limits, quantum state…
The life of a cell is governed by highly dynamical microscopic processes. Two notable examples are the diffusion of membrane receptors and the kinetics of transcription factors governing the rates of gene expression. Different fluorescence…
After receiving an X-ray photon, an X-ray detector is not operational for a duration known as deadtime. It is detector specific and its effect on the data depends upon the luminosity of the source. It reduces the observed photon count rate…
Optical observations with high time resolution are essential for understanding the origin of sub-millisecond timescale astronomical phenomena, including giant radio pulses from the Crab Pulsar. We have developed a high-speed imaging system…
This paper reported a bespoke adder-based deep learning network for time-domain fluorescence lifetime imaging (FLIM). By leveraging the l1-norm extraction method, we propose a 1-D Fluorescence Lifetime AdderNet (FLAN) without…
The increasing complexity of the recent photonic experiments challenges developing efficient multi-channel coincidence counting systems with high-level functionality. Here, we report a coincidence unit able to count detection events ranging…
Aberrations and multiple scattering in biological tissues critically distort light beams into highly complex speckle patterns. In this regard, digital optical phase conjugation (DOPC) is a promising technique enabling in-depth focusing.…
Photon correlation spectroscopy (PCS) is based on measuring the temporal correlation of the light intensity scattered by the investigated sample. A typical setup requires a temporally coherent light source. Here, we show that a…
This paper presents a new Bayesian model and algorithm used for depth and intensity profiling using full waveforms from the time-correlated single photon counting (TCSPC) measurement in the limit of very low photon counts. The model…
We study a simple modification to the conventional time of flight mass spectrometry (TOFMS) where a \emph{variable} and (pseudo)-\emph{random} pulsing rate is used which allows for traces from different pulses to overlap. This modification…
Detecting brief changes in time-series data remains a major challenge in fields where short-lived states carry meaning. In single-molecule localisation microscopy, this problem is particularly acute as fluorescent molecules used to tag…
Counting cells in fluorescent microscopy is a tedious, time-consuming task that researchers have to accomplish to assess the effects of different experimental conditions on biological structures of interest. Although such objects are…
Photonic lattices - arrays of optical waveguides - are powerful platforms for simulating a range of phenomena, including topological phases. While probing dynamics is possible in these systems, by reinterpreting the propagation direction as…
-In the Alvarez-Macovski method [R.E. Alvarez and A. Macovski, Phys. Med. Biol., 1976, 733-744], the attenuation coefficient is approximated as a linear combination of functions of energy multiplied by coefficients that depend on the…
Photon number resolving detectors are needed for a variety of applications including linear-optics quantum computing. Here we describe the use of time-multiplexing techniques that allows ordinary single photon detectors, such as silicon…
Lidar with direct time-of-flight (dToF) technology based on single-photon avalanche diode detectors (SPAD) has been widely adopted in various applications. However, a comprehensive theoretical understanding of its fundamental ranging…
We report, for the first time, a multi-confocal Fluorescence Correlation Spectroscopy (mFCS) technique which allows parallel measurements at different locations, by combining a Spatial Light Modulator (SLM), with an Electron Multiplying-CCD…