相关论文: Fluorescence decay data analysis correcting for de…
The excited state population of single solid-state emitters is subjected to energy fluctuations around the equilibrium driven by the bath and relaxation through the emission of phonons or photons. Simultaneous measurement of the associated…
This paper presents a novel pulse-reconstruction method well suited to sparsely sampled repetitive data, such as commonly arise from trains of ultrashort laser-pulses. Typically waveforms in such traces are fully instrument-limited by the…
Single photons are a vital resource for photonic quantum information processing. However, even state-of-the-art single photon sources based on photon-pair generation and heralding detection have only a low probability of delivering a single…
State-of-the-art technology for pulse counter electronics offers an important range of commercial devices, but such systems are usually expensive due to the complex logic used for this task. The use of counting electronics in conjunction…
We present a fast and accurate analytical method for fluorescence lifetime imaging microscopy (FLIM) using the extreme learning machine (ELM). We used extensive metrics to evaluate ELM and existing algorithms. First, we compared these…
Super-resolution microscopy is rapidly gaining importance as an analytical tool in the life sciences. A compelling feature is the ability to label biological units of interest with fluorescent markers in living cells and to observe them…
The random motion of molecules in living cells has consistently been reported to deviate from standard Brownian motion, a behavior coined as ``anomalous diffusion''. Fluorescence Correlation Spectroscopy (FCS) is a powerful method to…
Ultra-weak photon emission (UPE) from living systems is widely hypothesized to reflect un-derlying self-organization and long-range coordination in biological dynamics. However, distin-guishing biologically driven correlations from trivial…
The development of voltage-sensitive fluorescent probes suggests fluorescence lifetime as a promising readout for electrical activity in biological systems. Existing approaches fail to achieve the speed and sensitivity required for voltage…
We discuss the performance of a readout system, Fixed Pulse Shape Efficient Readout (FIPSER), to digitize signals from detectors with a fixed pulse shape. In this study we are mainly interested in the readout of fast photon detectors like…
The effective bandwidth of an energy dispersive x-ray fluorescence spectroscopy system is limited by the timing of incident photons. When multiple photons strike the detector within the processing time of the detector photon pile-up occurs…
We have performed a statistical characterization of the effect of afterpulsing in a free-running silicon single-photon detector by measuring the distribution of afterpulse waiting times in response to pulsed illumination and fitting it by a…
Imaging across both the full transverse spatial and temporal dimensions of a scene with high precision in all three coordinates is key to applications ranging from LIDAR to fluorescence lifetime imaging. However, compromises that sacrifice,…
Point-wise localization of individual fluorophores is a critical step in super-resolution microscopy and single particle tracking. Although the methods are limited by the accuracy in localizing individual flourophores, this point-wise…
Fourier ptychographic microscopy (FPM) is a recently proposed quantitative phase imaging technique with high resolution and wide field-of-view (FOV). In current FPM imaging platforms, systematic error sources come from the aberrations, LED…
This paper proposes a probabilistic approach for the detection and the tracking of particles in fluorescent time-lapse imaging. In the presence of a very noised and poor-quality data, particles and trajectories can be characterized by an a…
A detailed and accurate characterisation of silicon photomultiplier detectors is required for a better understanding of the signal and noise in many applications. The collected information is a valuable feedback to the manufacturers in…
Event-based image sensors provide microsecond temporal resolution but lack spectral discrimination, whereas diffractive spectral imagers encode wavelength information at conventional frame rates. We introduce a fluorescence microscopy…
A photonics-assisted microwave pulse detection and frequency measurement scheme is proposed. The unknown microwave pulse is converted to the optical domain and then injected into a fiber loop for pulse replication, which makes it easier to…
The puzzle of "sticky collisions," in which molecular collision complexes exhibit unexpectedly long lifetimes, remains an unresolved mystery. A central challenge to solving this mystery is that traditional close-coupling calculations remain…