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The seemingly stochastic transient dynamics of neocortical circuits observed in vivo have been hypothesized to represent a signature of ongoing stochastic inference. In vitro neurons, on the other hand, exhibit a highly deterministic…

神经元与认知 · 定量生物学 2017-03-14 Mihai A. Petrovici , Johannes Bill , Ilja Bytschok , Johannes Schemmel , Karlheinz Meier

We briefly review and highlight the consequences of rigorous and exact results obtained in \cite{cessac:10}, characterizing the statistics of spike trains in a network of leaky Integrate-and-Fire neurons, where time is discrete and where…

适应与自组织系统 · 物理学 2010-08-31 Bruno Cessac , Hassan Nasser , Juan-Carlos Vasquez

Contemporary neuroscience has embraced network science to study the complex and self-organized structure of the human brain; one of the main outstanding issues is that of inferring from measure data, chiefly functional Magnetic Resonance…

最优化与控制 · 数学 2017-03-31 Giulia Prando , Mattia Zorzi , Alessandra Bertoldo , Alessandro Chiuso

In this paper we address the question of statistical model selection for a class of stochastic models of biological neural nets. Models in this class are systems of interacting chains with memory of variable length. Each chain describes the…

统计理论 · 数学 2018-12-19 A. Duarte , A. Galves , E. Löcherbach , G. Ost

New experimental methods make it possible to measure the expression levels of many genes, simultaneously, in snapshots from thousands or even millions of individual cells. Current approaches to analyze these experiments involve clustering…

We address the problem of finding patterns from multi-neuronal spike trains that give us insights into the multi-neuronal codes used in the brain and help us design better brain computer interfaces. We focus on the synchronous firings of…

神经与进化计算 · 计算机科学 2010-06-09 Raajay Viswanathan , P. S. Sastry , K. P. Unnikrishnan

Spiking Neural Networks (SNNs) capture the information processing mechanism of the brain by taking advantage of spiking neurons, such as the Leaky Integrate-and-Fire (LIF) model neuron, which incorporates temporal dynamics and transmits…

神经与进化计算 · 计算机科学 2024-01-18 Zexiang Yi , Jing Lian , Yunliang Qi , Zhaofei Yu , Huajin Tang , Yide Ma , Jizhao Liu

Understanding specifically where a model focuses on within an image is critical for human interpretability of the decision-making process. Deep learning-based solutions are prone to learning coincidental correlations in training datasets,…

计算机视觉与模式识别 · 计算机科学 2024-10-22 Aidan Boyd , Mohamed Trabelsi , Huseyin Uzunalioglu , Dan Kushnir

This work maps deep neural networks to classical Ising spin models, allowing them to be described using statistical thermodynamics. The density of states shows that structures emerge in the weights after they have been trained --…

统计力学 · 物理学 2022-09-20 Dusan Stosic , Darko Stosic , Borko Stosic

This paper models the dynamics of a large set of interacting neurons within the framework of statistical field theory. We use a method initially developed in the context of statistical field theory [44] and later adapted to complex systems…

神经元与认知 · 定量生物学 2022-05-25 Pierre Gosselin , Aïleen Lotz , Marc Wambst

Many biological neuronal networks exhibit highly variable spiking activity. Balanced networks offer a parsimonious model of this variability. In balanced networks, strong excitatory synaptic inputs are canceled by strong inhibitory inputs…

神经元与认知 · 定量生物学 2016-05-04 Ryan Pyle , Robert Rosenbaum

Cortical circuits exhibit high levels of response diversity, even across apparently uniform neuronal populations. While emerging data-driven approaches exploit this heterogeneity to infer effective models of cortical circuit computation…

神经元与认知 · 定量生物学 2025-11-06 Mohammadreza Soltanipour , Stefan Treue , Fred Wolf

Information processing in the brain requires integration of information over time. Such an integration can be achieved if signals are maintained in the network activity for the required period, as quantified by the intrinsic timescale.…

Understanding how neurons coordinate their activity is a fundamental question in neuroscience, with implications for learning, memory, and neurological disorders. Calcium imaging has emerged as a powerful method to observe large-scale…

统计方法学 · 统计学 2026-03-03 Laura D'Angelo , Francesco Denti , Antonio Canale , Michele Guindani

Lattice models exhibit significant potential in investigating phase transitions, yet they encounter numerous computational challenges. To address these issues, this study introduces a Monte Carlo-based approach that transforms lattice…

统计力学 · 物理学 2024-08-28 Yonglong Ding

The central question of systems biology is to understand how individual components of a biological system such as genes or proteins cooperate in emerging phenotypes resulting in the evolution of diseases. As living cells are open systems in…

定量方法 · 定量生物学 2019-08-20 Jeyashree Krishnan , Reza Torabi , Edoardo Di Napoli , Andreas Schuppert

For energy-efficient computation in specialized neuromorphic hardware, we present spiking neural coding, an instantiation of a family of artificial neural models grounded in the theory of predictive coding. This model, the first of its…

神经与进化计算 · 计算机科学 2022-08-09 Alexander Ororbia

We give an approximate solution to the difficult inverse problem of inferring the topology of an unknown network from given time-dependent signals at the nodes. For example, we measure signals from individual neurons in the brain, and infer…

生物物理 · 物理学 2021-01-27 Corey Weistuch , Luca Agozzino , Lilianne R. Mujica-Parodi , Ken A. Dill

How do humans and animals perform trial-and-error learning when the space of possibilities is infinite? In a previous study, we used an interval timing production task and discovered an updating strategy in which the agent adjusted the…

神经元与认知 · 定量生物学 2022-05-10 Jing Wang , Yousuf El-Jayyousi , Ilker Ozden

Probabilistic inference offers a principled framework for understanding both behaviour and cortical computation. However, two basic and ubiquitous properties of cortical responses seem difficult to reconcile with probabilistic inference:…

神经元与认知 · 定量生物学 2017-01-03 Laurence Aitchison , Máté Lengyel