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The understanding of neurodegenerative diseases undoubtedly passes through the study of human brain white matter fiber tracts. To date, diffusion magnetic resonance imaging (dMRI) is the unique technique to obtain information about the…

机器学习 · 计算机科学 2012-07-04 Romain Giot , Christophe Charrier , Maxime Descoteaux

In the last years in-vivo tractography has assumed an important role in neurosciences, for both research and clinical applications such as non-invasive investigation of brain connectivity and presurgical planning in neurosurgery. In more…

The thickness of the cortical band is linked to various neurological and psychiatric conditions, and is often estimated through surface-based methods such as Freesurfer in MRI studies. The DiReCT method, which calculates cortical thickness…

图像与视频处理 · 电气工程与系统科学 2023-07-24 Richard McKinley , Christian Rummel

Diffusion kurtosis imaging is an extension of diffusion tensor imaging that provides scientifically and clinically valuable information about brain tissue microstructure but suffers from poor robustness to noise, especially in voxels…

We demonstrate a novel approach to the reconstruction of scanning probe x-ray diffraction tomography data with anisotropic poly crystalline samples. The method involves reconstructing a voxel map containing an orientation distribution…

Cortical thickness measurements from magnetic resonance imaging, an important biomarker in many neurodegenerative and neurological disorders, are derived by many tools from an initial voxel-wise tissue segmentation. White matter (WM)…

图像与视频处理 · 电气工程与系统科学 2025-03-27 Vinzenz Uhr , Ivan Diaz , Christian Rummel , Richard McKinley

Diffusion magnetic resonance imaging offers unique in vivo sensitivity to tissue microstructure in brain white matter, which undergoes significant changes during development and is compromised in virtually every neurological disorder. Yet,…

White matter tract microstructure has been shown to influence neuropsychological scores of cognitive performance. However, prediction of these scores from white matter tract data has not been attempted. In this paper, we propose a…

Standard fMRI connectivity analyses depend on aggregating the time series of individual voxels within regions of interest (ROIs). In certain cases, this spatial aggregation implies a loss of valuable functional and anatomical information…

神经元与认知 · 定量生物学 2019-08-12 Ruben Sanchez-Romero , Joseph D. Ramsey , Kun Zhang , Clark Glymour

Expansion of diffusion MRI (dMRI) both into the realm of strong gradients, and into accessible imaging with portable low-field devices, brings about the challenge of gradient nonlinearities. Spatial variations of the diffusion gradients…

White matter segmentation methods from diffusion magnetic resonance imaging range from streamline clustering-based approaches to bundle mask delineation, but none have proposed a pediatric-specific approach. We hypothesize that a deep…

Diffusion-weighted MR imaging (DWI) is the only method we currently have to measure connections between different parts of the human brain in vivo. To elucidate the structure of these connections, algorithms for tracking bundles of axonal…

机器学习 · 统计学 2014-12-05 Charles Zheng , Franco Pestilli , Ariel Rokem

Whole-brain neural connectivity data are now available from viral tracing experiments, which reveal the connections between a source injection site and elsewhere in the brain. These hold the promise of revealing spatial patterns of…

神经元与认知 · 定量生物学 2016-10-27 Kameron Decker Harris , Stefan Mihalas , Eric Shea-Brown

Topo-Tomography (TT) is a synchrotron-based X-ray diffraction imaging technique used to characterize grain shape and crystal orientation in polycrystalline samples. This work aims to provide a decisive and fundamental understanding of 3D…

计算物理 · 物理学 2025-10-13 Zheheng Liu , Nicola Vigano , Henry Proudhon , Wolfgang Ludwig

A major interest in longitudinal neuroimaging studies involves investigating voxel-level neuroplasticity due to treatment and other factors across visits. However, traditional voxel-wise methods are beset with several pitfalls, which can…

神经元与认知 · 定量生物学 2023-10-19 Suprateek Kundu , Alec Reinhardt , Serena Song , Joo Han , M. Lawson Meadows , Bruce Crosson , Venkatagiri Krishnamurthy

Disease in the brain is often associated with subtle, spatially diffuse, or complex tissue changes that may lie beneath the level of gross visual inspection, even on magnetic resonance imaging (MRI). Unfortunately, current computer-assisted…

计算机视觉与模式识别 · 计算机科学 2017-05-16 Shinjini Kundu , Soheil Kolouri , Kirk I Erickson , Arthur F Kramer , Edward McAuley , Gustavo K Rohde

Non-destructive extraction of the target internal part, such as batteries and motors, by cutting surrounding structures is crucial at recycling and disposal sites. However, the diversity of products and the lack of information on…

计算机视觉与模式识别 · 计算机科学 2026-03-03 Takumi Hachimine , Yuhwan Kwon , Cheng-Yu Kuo , Tomoya Yamanokuchi , Takamitsu Matsubara

Processing of Diffusion MRI data obtained from High Angular Resolution measurements consists of a series of steps, starting with the estimation of an orientation distribution function (ODF), which is then used as input for e.g. tractography…

数值分析 · 数学 2015-12-23 T. Hohage , C. Rügge

A novel approach is presented for group statistical analysis of diffusion weighted MRI datasets through voxelwise Orientation Distribution Functions (ODF). Recent advances in MRI acquisition make it possible to use high quality diffusion…

Diffusion-weighted magnetic resonance imaging (DWI) and fiber tractography are the only methods to measure the structure of the white matter in the living human brain. The diffusion signal has been modelled as the combined contribution from…

机器学习 · 统计学 2014-09-29 Charles Zheng , Franco Pestilli , Ariel Rokem