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The purpose of this work is to develop a framework for single-subject analysis of diffusion tensor imaging (DTI) data. This framework (termed TOADDI) is capable of testing whether an individual tract as represented by the major eigenvector…

This paper presents DDTracking, a novel deep generative framework for diffusion MRI tractography that formulates streamline propagation as a conditional denoising diffusion process. In DDTracking, we introduce a dual-pathway encoding…

计算机视觉与模式识别 · 计算机科学 2026-02-04 Yijie Li , Wei Zhang , Xi Zhu , Ye Wu , Yogesh Rathi , Lauren J. O'Donnell , Fan Zhang

Diffusion-weighted imaging (DWI) is a type of Magnetic Resonance Imaging (MRI) technique sensitised to the diffusivity of water molecules, offering the capability to inspect tissue microstructures and is the only in-vivo method to…

计算机视觉与模式识别 · 计算机科学 2024-09-17 Sheng Chen , Zihao Tang , Mariano Cabezas , Xinyi Wang , Arkiev D'Souza , Michael Barnett , Fernando Calamante , Weidong Cai , Chenyu Wang

Parcellation of white matter tractography provides anatomical features for disease prediction, anatomical tract segmentation, surgical brain mapping, and non-imaging phenotype classifications. However, parcellation does not always reach…

计算机视觉与模式识别 · 计算机科学 2024-09-23 Yui Lo , Yuqian Chen , Fan Zhang , Dongnan Liu , Leo Zekelman , Suheyla Cetin-Karayumak , Yogesh Rathi , Weidong Cai , Lauren J. O'Donnell

Our understanding of the human connectome is fundamentally limited by the resolution of diffusion MR images. Reconstructing a connectome's constituent neural pathways with tractography requires following a continuous field of fiber…

计算机视觉与模式识别 · 计算机科学 2023-12-12 Tyler Spears , P. Thomas Fletcher

This article introduces a new methodology for reconstructing the white matter fiber pathways of brain in diffusion MRI. Usually, the signal intensity values will be lesser in the direction of higher diffusivity. The proposed approach picks…

神经元与认知 · 定量生物学 2022-07-26 Ashishi Puri , Sanjeev Kumar

Current brain white matter fiber tracking techniques show a number of problems, including: generating large proportions of streamlines that do not accurately describe the underlying anatomy; extracting streamlines that are not supported by…

图像与视频处理 · 电气工程与系统科学 2021-08-03 Jon Haitz Legarreta , Laurent Petit , François Rheault , Guillaume Theaud , Carl Lemaire , Maxime Descoteaux , Pierre-Marc Jodoin

Trajectory planning is crucial for the safe driving of autonomous vehicles in highway traffic flow. Currently, some advanced trajectory planning methods utilize spatio-temporal voxels to construct feasible regions and then convert…

机器人学 · 计算机科学 2023-10-05 Zhiqiang Jian , Songyi Zhang , Lingfeng Sun , Wei Zhan , Masayoshi Tomizuka , Nanning Zheng

Neuroimaging measures of the brain's white matter connections can enable the prediction of non-imaging phenotypes, such as demographic and cognitive measures. Existing works have investigated traditional microstructure and connectivity…

计算机视觉与模式识别 · 计算机科学 2023-05-23 Wan Liu , Yuqian Chen , Chuyang Ye , Nikos Makris , Yogesh Rathi , Weidong Cai , Fan Zhang , Lauren J. O'Donnell

Accurately identifying white matter tracts in medical images is essential for various applications, including surgery planning and tract-specific analysis. Supervised machine learning models have reached state-of-the-art solving this task…

图像与视频处理 · 电气工程与系统科学 2023-08-04 Robin Peretzke , Klaus Maier-Hein , Jonas Bohn , Yannick Kirchhoff , Saikat Roy , Sabrina Oberli-Palma , Daniela Becker , Pavlina Lenga , Peter Neher

Diffusion magnetic resonance imaging, a non-invasive tool to infer white matter fiber connections, produces a large number of streamlines containing a wealth of information on structural connectivity. The size of these tractography outputs…

计算机视觉与模式识别 · 计算机科学 2018-04-17 Kuldeep Kumar , Kaleem Siddiqi , Christian Desrosiers

Understanding the relationship between the dynamics of neural processes and the anatomical substrate of the brain is a central question in neuroscience. On the one hand, modern neuroimaging technologies, such as diffusion tensor imaging,…

Ultra-low-field (ULF) MRI is emerging as an alternative modality to high-field (HF) MRI due to its lower cost, minimal siting requirements, portability, and enhanced accessibility factors that enable large-scale deployment. Although ULF-MRI…

We present a rotation-equivariant unsupervised learning framework for the sparse deconvolution of non-negative scalar fields defined on the unit sphere. Spherical signals with multiple peaks naturally arise in Diffusion MRI (dMRI), where…

图像与视频处理 · 电气工程与系统科学 2021-02-19 Axel Elaldi , Neel Dey , Heejong Kim , Guido Gerig

This paper introduces a novel methodology to integrate human brain connectomics and parcellation for brain tumor segmentation and survival prediction. For segmentation, we utilize an existing brain parcellation atlas in the MNI152 1mm space…

计算机视觉与模式识别 · 计算机科学 2019-02-13 Po-Yu Kao , Thuyen Ngo , Angela Zhang , Jefferson W. Chen , B. S. Manjunath

White matter (WM) tract segmentation is a crucial step for brain connectivity studies. It is performed on diffusion magnetic resonance imaging (dMRI), and deep neural networks (DNNs) have achieved promising segmentation accuracy. Existing…

图像与视频处理 · 电气工程与系统科学 2023-09-26 Wan Liu , Chuyang Ye

Human skill learning requires fine-scale coordination of distributed networks of brain regions that are directly linked to one another by white matter tracts to allow for effective information transmission. Yet how individual differences in…

神经元与认知 · 定量生物学 2016-10-25 Ari E. Kahn , Marcelo G. Mattar , Jean M. Vettel , Nicholas F. Wymbs , Scott T. Grafton , Danielle S. Bassett

Brain structural networks are often represented as discrete adjacency matrices with elements summarizing the connectivity between pairs of regions of interest (ROIs). These ROIs are typically determined a-priori using a brain atlas. The…

统计计算 · 统计学 2023-08-11 William Consagra , Martin Cole , Xing Qiu , Zhengwu Zhang

Tractography fiber clustering using diffusion MRI (dMRI) is a crucial strategy for white matter (WM) parcellation. Current methods primarily use the geometric information of fibers (i.e., the spatial trajectories) to group similar fibers…

图像与视频处理 · 电气工程与系统科学 2024-12-17 Jin Wang , Bocheng Guo , Yijie Li , Junyi Wang , Yuqian Chen , Jarrett Rushmore , Nikos Makris , Yogesh Rathi , Lauren J O'Donnell , Fan Zhang

Axons in white matter have been shown to have varying geometries within a bundle using ex vivo imaging techniques, but what does this mean for diffusion MRI (dMRI) based spherical deconvolution (SD)? SD attempts to estimate the fibre…

医学物理 · 物理学 2022-03-04 Ross Callaghan , Daniel C. Alexander , Marco Palombo , Hui Zhang