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The effect of the microscopic structure of a pore on polymer translocation is studied using Langevin dynamics simulation, and the consequence of introducing patterned stickiness inside the pore is investigated. It is found that the…

软凝聚态物质 · 物理学 2013-02-01 Jack A. Cohen , Abhishek Chaudhuri , Ramin Golestanian

Single file translocation of a homopolymer through an active channel under the presence of a driving force is studied using Langevin dynamics simulation. It is shown that a channel with sticky walls and oscillating width could lead to…

软凝聚态物质 · 物理学 2013-02-01 Jack A. Cohen , Abhishek Chaudhuri , Ramin Golestanian

Polymer translocation has long been a topic of interest in the field of biological physics given its relevance in both biological (protein and DNA/RNA translocation through nuclear and cell membranes) and technological processes (nanopore…

软凝聚态物质 · 物理学 2023-09-11 Alejandro Sainz-Agost , Fernando Falo , Alessandro Fiasconaro

We study translocation of semiflexible polymers driven by force $f_d$ inside a nanometer-scale pore using our three-dimensional Langevin dynamics model. We show that the translocation time $\tau$ increases with increasing bending rigidity…

生物物理 · 物理学 2018-06-27 Pauli M. Suhonen , Riku P. Linna

We investigate the translocation dynamics of heteropolymers driven through a nanopore using a constant temperature Langevin thermostat. Specifically, we consider heteropolymers consisting of two types of monomers labeled A and B, which are…

软凝聚态物质 · 物理学 2007-05-23 Kaifu Luo , Tapio Ala-Nissila , See-Chen Ying , Aniket Bhattacharya

We perform two-dimensional Langevin dynamics simulations of electric-field driven polymer translocation through an attractive nanopore. We investigate the effect of the location of the attractive region using different pore patterns. This…

软凝聚态物质 · 物理学 2015-06-15 F Piguet , D P Foster

We study the translocation of a flexible polymer through extended patterned pores using molecular dynamics (MD) simulations. We consider cylindrical and conical pore geometries that can be controlled by the angle of the pore apex $\alpha$.…

软凝聚态物质 · 物理学 2026-02-11 Andri Sharma , Abhishek Chaudhuri , Rajeev Kapri

We have used Langevin dynamics to simulate the forced translocation of linked polymer rings through a narrow pore. For fixed size (i.e. fixed number of monomers) the translocation time depends on the link type and on whether the rings are…

统计力学 · 物理学 2020-06-24 Michele Caraglio , Enzo Orlandini , Stuart G Whittington

The transport of polymers with folded configurations across membrane pores is investigated theoretically by analyzing simple discrete stochastic models. The translocation dynamics is viewed as a sequence of two events: motion of the folded…

统计力学 · 物理学 2009-11-13 Stanislav Kotsev , Anatoly B. Kolomeisky

We investigate the influence of polymer-pore interactions on the translocation dynamics using Langevin dynamics simulations. An attractive interaction can greatly improve translocation probability. At the same time, it also increases…

软凝聚态物质 · 物理学 2007-10-01 Kaifu Luo , Tapio Ala-Nissila , See-chen Ying , Aniket Bhattacharya

Langevin Dynamics simulations of polymer translocation are performed where the polymer is stretched via two opposing forces applied on the first and last monomer before and during translocation. In this setup, polymer translocation is…

软凝聚态物质 · 物理学 2018-08-08 Hendrick W. de Haan , David Sean , Gary W. Slater

The transport of deformable particles through porous media underlies a wealth of applications ranging from filtration to oil recovery to the transport and spreading of biological agents. Using direct numerical simulations, we analyze the…

软凝聚态物质 · 物理学 2020-06-09 Brato Chakrabarti , Charles Gaillard , David Saintillan

Mesh-like structures, such as mucus gel or cytoskeleton networks, are ubiquitous in biological systems. These intricate structures are composed of cross-linked, semi-flexible bio-filaments, crucial to numerous biological processes. In many…

软凝聚态物质 · 物理学 2024-01-10 Yeongjin Kim , Won Kyu Kim , Jae-Hyung Jeon

We investigate several scaling properties of a translocating homopolymer through a thin pore driven by an external field present inside the pore only using Langevin Dynamics (LD) simulation in three dimension (3D). Specifically motivated by…

We study the translocation of a semiflexible polymer through a conical channel with attractive surface interactions and a driving force which varies spatially inside the channel. Using the results of the translocation dynamics of a flexible…

软凝聚态物质 · 物理学 2022-11-15 Andri Sharma , Rajeev Kapri , Abhishek Chaudhuri

We develop a theory for polymer translocation driven by a time-dependent force through an oscillating nanopore. To this end, we extend the iso-flux tension propagation theory (IFTP) [Sarabadani \textit{et al., J. Chem. Phys.}, 2014,…

统计力学 · 物理学 2015-09-02 Jalal Sarabadani , Timo Ikonen , Tapio Ala-Nissila

Brownian motion and viscoelasticity of semiflexible polymers is a subject that has been studied for many years. Still, rigorous analysis has been hindered due to the difficulty in handling the constraint that polymer chains cannot be…

软凝聚态物质 · 物理学 2024-05-22 Zhongqiang Xiong , Ryohei Seto , Masao Doi

We study the driven translocation of a flexible polymer through an interacting conical pore using Langevin dynamics simulations. We find that, for a fixed value of externally applied force and pore polymer interaction strength, the mean…

软凝聚态物质 · 物理学 2021-02-17 Rajneesh Kumar , Abhishek Chaudhuri , Rajeev Kapri

We present a numerical study of forced polymer translocation by using two separate pore models. Both of them have been extensively used in previous forced translocation studies. We show that variations in the pore model affect the forced…

生物物理 · 物理学 2015-05-19 V. V. Lehtola , K. Kaski , R. P. Linna

We present using simple scaling arguments and one step replica symmetry breaking a theory for the localization of semiflexible polymers in a quenched random environment. In contrast to completely flexible polymers, localization of…

软凝聚态物质 · 物理学 2009-11-10 Arti Dua , Thomas A. Vilgis
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