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In neuroscience, functional brain connectivity describes the connectivity between brain regions that share functional properties. Neuroscientists often characterize it by a time series of covariance matrices between functional measurements…

统计方法学 · 统计学 2019-07-09 Zhenhua Lin , Dehan Kong , Qiang Sun

The modular structure of brain networks supports specialized information processing, complex dynamics, and cost-efficient spatial embedding. Inter-individual variation in modular structure has been linked to differences in performance,…

Modular structure is ubiquitous among real-world networks from related proteins to social groups. Here we analyze the modular organization of brain networks at a large-scale (voxel level) extracted from functional magnetic resonance imaging…

数据分析、统计与概率 · 物理学 2009-04-16 M. Valencia , M. A. Pastor , MA. Fernandez-Seara , J. Artieda , J. Martinerie , M. Chavez

We present an approach to study functional segregation and integration in the living brain based on community structure decomposition determined by maximum modularity. We demonstrate this method with a network derived from functional…

神经元与认知 · 定量生物学 2007-05-23 Adam J. Schwarz , Alessandro Gozzi , Angelo Bifone

Recent analyses combining advanced theoretical techniques and high-quality data from thousands of simultaneously recorded neurons provide strong support for the hypothesis that neural dynamics operate near the edge of instability across…

神经元与认知 · 定量生物学 2024-03-25 Rubén Calvo , Carles Martorell , Guillermo B. Morales , Serena Di Santo , Miguel A. Muñoz

Brain networks are expected to be modular. However, existing techniques for estimating a network's modules make it difficult to assess the influence of organizational principles such as wiring cost reduction on the detected modules. Here,…

The human brain is a complex network of interconnected brain regions organized into functional modules with distinct roles in cognition and behavior. An important question concerns the persistence and stability of these modules over the…

神经元与认知 · 定量生物学 2015-10-28 Richard F. Betzel , Bratislav Mišić , Ye He , Jeffrey Rumschlag , Xi-Nian Zuo , Olaf Sporns

Functional differentiation in the brain emerges as distinct regions specialize and is key to understanding brain function as a complex system. Previous research has modeled this process using artificial neural networks with specific…

神经元与认知 · 定量生物学 2025-11-17 Yuki Tomoda , Ichiro Tsuda , Yutaka Yamaguti

The dynamic core hypothesis posits that consciousness is correlated with simultaneously integrated and differentiated assemblies of transiently synchronized brain regions. We represented time-dependent functional interactions using dynamic…

神经元与认知 · 定量生物学 2024-06-19 Sofia Morena del Pozo , Helmut Laufs , Vincent Bonhomme , Steven Laureys , Pablo Balenzuela , Enzo Tagliazucchi

Music, being a multifaceted stimulus evolving at multiple timescales, modulates brain function in a manifold way that encompasses not only the distinct stages of auditory perception but also higher cognitive processes like memory and…

神经元与认知 · 定量生物学 2018-02-06 Dimitrios A. Adamos , Nikolaos Laskaris , Sifis Micheloyannis

Localizing neuronal activity in the brain, both in time and in space, is a central challenge to advance the understanding of brain function. Because of the inability of any single neuroimaging techniques to cover all aspects at once, there…

神经元与认知 · 定量生物学 2013-07-09 Yaroslav O. Halchenko , Michael Hanke , James V. Haxby , Stephen Jose Hanson , Christoph S. Herrmann

Adaptive behavior, cognition and emotion are the result of a bewildering variety of brain spatiotemporal activity patterns. An important problem in neuroscience is to understand the mechanism by which the human brain's 100 billion neurons…

As a person learns a new skill, distinct synapses, brain regions, and circuits are engaged and change over time. In this paper, we develop methods to examine patterns of correlated activity across a large set of brain regions. Our goal is…

神经元与认知 · 定量生物学 2013-10-31 Danielle S. Bassett , Nicholas F. Wymbs , M. Puck Rombach , Mason A. Porter , Peter J. Mucha , Scott T. Grafton

Foundation models have shown remarkable success in fitting biological visual systems; however, their black-box nature inherently limits their utility for understanding brain function. Here, we peek inside a SOTA foundation model of neural…

神经元与认知 · 定量生物学 2026-01-30 Johannes Bertram , Luciano Dyballa , Anderson Keller , Savik Kinger , Steven W. Zucker

Emerging evidence shows that the modular organization of the human brain allows for better and efficient cognitive performance. Many of these cognitive functions are very fast and occur in subsecond time scale such as the visual object…

神经元与认知 · 定量生物学 2018-08-01 J. Rizkallah , P. Benquet , A. Kabbara , O. Dufor , F. Wendling , M. Hassan

Dynamic functional connectivity analysis provides valuable information for understanding brain functional activity underlying different cognitive processes. Besides sliding window based approaches, a variety of methods have been developed…

计算机视觉与模式识别 · 计算机科学 2018-09-18 Hongming Li , Yong Fan

We describe techniques for the robust detection of community structure in some classes of time-dependent networks. Specifically, we consider the use of statistical null models for facilitating the principled identification of structural…

数据分析、统计与概率 · 物理学 2013-04-16 Danielle S. Bassett , Mason A. Porter , Nicholas F. Wymbs , Scott T. Grafton , Jean M. Carlson , Peter J. Mucha

Neural signals are characterized by rich temporal and spatiotemporal dynamics that reflect the organization of cortical networks. Theoretical research has shown how neural networks can operate at different dynamic ranges that correspond to…

神经元与认知 · 定量生物学 2017-07-05 Luca Ambrogioni , Marcel A. J. van Gerven , Eric Maris

MRI-based modeling of brain networks has been widely used to understand functional and structural interactions and connections among brain regions, and factors that affect them, such as brain development and disease. Graph mining on brain…

机器学习 · 计算机科学 2022-05-18 Haoteng Tang , Xiyao Fu , Lei Guo , Yalin Wang , Scott Mackin , Olusola Ajilore , Alex Leow , Paul Thompson , Heng Huang , Liang Zhan

Elucidating the intricate relationship between brain structure and function, both in healthy and pathological conditions, is a key challenge for modern neuroscience. Recent technical and methodological progress in neuroimaging has helped…

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