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The proper biological functioning of proteins often relies on the occurrence of coordinated fluctuations around their native structure, or of wider and sometimes highly elaborated motions. Coarse-grained elastic-network descriptions are…

生物大分子 · 定量生物学 2013-10-17 Yves Dehouck , Alexander S. Mikhailov

We present a novel simulation technique derived from Brownian cluster dynamics used so far to study the isotropic colloidal aggregation. It now implements the classical Kern-Frenkel potential to describe patchy interactions between…

软凝聚态物质 · 物理学 2015-06-19 Achutha Prabhu , Sujin B. Babu , Jorge S. Dolado , J. -C. Gimel

The nonequilibrium activity taking place in a living cell can be monitored with a tracer embedded in the medium. While microrheology experiments based on optical manipulation of such probes have become increasingly standard, we put forward…

软凝聚态物质 · 物理学 2014-10-31 Étienne Fodor , Kiyoshi Kanazawa , Hisao Hayakawa , Paolo Visco , Frédéric van Wijland

We consider the two dimensional motion of a particle into a confining potential, subjected to Brownian forces, associated with two different temperatures on the orthogonal directions. Exact solutions are obtained for an asymmetric harmonic…

统计力学 · 物理学 2018-05-23 Vincent Mancois , Bruno Marcos , Pascal Viot , David Wilkowski

The long time dynamics of large particles trapped in two inhomogeneous turbulent shear flows is studied experimentally. Both flows present a common feature, a shear region that separates two colliding circulations, but with different…

流体动力学 · 物理学 2016-03-02 N Machicoane , M López-Caballero , L Fiabane , J-F Pinton , M Bourgoin , J Burguete , R Volk

The Brownian motion of microscopic particles is driven by the collisions with the molecules of the surrounding fluid. The noise associated with these collisions is not white, but coloured due, e.g., to the presence of hydrodynamic memory.…

统计力学 · 物理学 2012-10-04 Scott Hottovy , Giovanni Volpe , Jan Wehr

Correct prediction of particle transport by surface waves is crucial in many practical applications such as search and rescue or salvage operations and pollution tracking and clean-up efforts. Recent results have indicated transport by…

流体动力学 · 物理学 2023-01-26 D. Eeltink , R. Calvert , J. E. Swagemakers , Qian Xiao , T. S. van den Bremer

We study the tracking problem, namely, estimating the hidden state of an object over time, from unreliable and noisy measurements. The standard framework for the tracking problem is the generative framework, which is the basis of solutions…

机器学习 · 计算机科学 2010-01-19 Kamalika Chaudhuri , Yoav Freund , Daniel Hsu

For systems in an externally controllable time-dependent potential, the optimal protocol minimizes the mean work spent in a finite-time transition between two given equilibrium states. For overdamped dynamics which ignores inertia effects,…

统计力学 · 物理学 2008-07-23 Alex Gomez-Marin , Tim Schmiedl , Udo Seifert

We present an analysis of the stationary distributions of run-and-tumble particles trapped in external potentials in terms of a thermophoretic potential, that emerges when trapped active motion is mapped to trapped passive Brownian motion…

统计力学 · 物理学 2019-02-06 Francisco J. Sevilla , Alejandro V. Arzola , Enrique Puga Cital

Quadratic trapping potentials are widely used to experimentally probe biopolymers and molecular machines and drive transitions in steered molecular-dynamics simulations. Approximating energy landscapes as locally quadratic, we design…

统计力学 · 物理学 2022-08-11 Steven Blaber , David A. Sivak

We reinvestigate the validity of mapping the problem of two onsite interacting particles in a random potential onto an effective random matrix model. To this end we first study numerically how the non-interacting basis is coupled by the…

无序系统与神经网络 · 物理学 2015-06-25 Thomas Vojta , Rudolf A. Roemer , Michael Schreiber

Simulations on a Lennard-Jones computer glass are performed to study effects arising from defects in glasses at low temperatures. The numerical analysis reveals that already a low concentration of defects may dramatically change the low…

统计力学 · 物理学 2009-10-30 Andreas Heuer , Peter Neu

The random energy landscapes developed by speckle fields can be used to confine and manipulate a large number of micro-particles with a single laser beam. By means of molecular dynamics simulations, we investigate the static and dynamic…

统计力学 · 物理学 2014-08-22 M. Paoluzzi , R. Di Leonardo , L. Angelani

Employing a recently developed method that is numerically accurate within a model space simulating the real-time dynamics of few-body systems interacting with macroscopic environmental quantum fields, we analyze the full dynamics of an…

量子物理 · 物理学 2013-03-07 Javier Prior , Inés de Vega , Alex W. Chin , Susana F. Huelga , Martin B. Plenio

Optical tweezers find applications in various fields, ranging from biology to physics. One of the fundamental steps necessary to perform quantitative measurements using trapped particles is the calibration of the tweezer's spring constant.…

量子物理 · 物理学 2020-06-05 Bruno Melo , Felipe Almeida , Guilherme Temporão , Thiago Guerreiro

We study interacting active Brownian particles (ABPs) with a space-dependent swim velocity via simulation and theory. We find that, although an equation of state exists, a mechanical equilibrium does not apply to ABPs in activity…

软凝聚态物质 · 物理学 2024-12-13 Adam Wysocki , Anil K. Dasanna , Heiko Rieger

Observation of the Brownian motion of a small probe interacting with its environment is one of the main strategies to characterize soft matter. Essentially two counteracting forces govern the motion of the Brownian particle. First, the…

We examine challenges to sampling from Boltzmann distributions associated with multiscale energy landscapes. The multiscale features, or "roughness," corresponds to highly oscillatory, but bounded, perturbations of a smooth landscape.…

数值分析 · 数学 2020-07-02 Petr Plecháč , Gideon Simpson

Accurately knowing uncertainties in appearance-based gaze tracking is critical for ensuring reliable downstream applications. Due to the lack of individual uncertainty labels, current uncertainty-aware approaches adopt probabilistic models…

计算机视觉与模式识别 · 计算机科学 2026-03-13 Qiaojie Zheng , Jiucai Zhang , Xiaoli Zhang