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The simulation of the behavior of the human brain is one of the most ambitious challenges today with a non-end of important applications. We can find many different initiatives in the USA, Europe and Japan which attempt to achieve such a…

分布式、并行与集群计算 · 计算机科学 2020-05-14 Pedro Valero-Lara , Raül Sirvent , Antonio J. Peña , Jesús Labarta

We describe a scalable database cluster for the spatial analysis and annotation of high-throughput brain imaging data, initially for 3-d electron microscopy image stacks, but for time-series and multi-channel data as well. The system was…

Neuromorphic computing has come to refer to a variety of brain-inspired computers, devices, and models that contrast the pervasive von Neumann computer architecture. This biologically inspired approach has created highly connected synthetic…

The brain is a complex organ characterized by heterogeneous patterns of structural connections supporting unparalleled feats of cognition and a wide range of behaviors. New noninvasive imaging techniques now allow these patterns to be…

神经元与认知 · 定量生物学 2020-04-03 Christopher W. Lynn , Danielle S. Bassett

The principled design and discovery of biologically- and physically-informed models of neuronal dynamics has been advancing since the mid-twentieth century. Recent developments in artificial intelligence (AI) have accelerated this progress.…

Elucidating the language-brain relationship requires bridging the methodological gap between the abstract theoretical frameworks of linguistics and the empirical neural data of neuroscience. Serving as an interdisciplinary cornerstone,…

神经元与认知 · 定量生物学 2026-02-16 Fudong Zhang , Bo Chai , Yujie Wu , Wai Ting Siok , Nizhuan Wang

The human brain is the most complex object of study we encounter today. Mapping the neuronal-level connections between the more than 80 billion neurons in the brain is a hopeless task for science. By the recent advancement of magnetic…

神经元与认知 · 定量生物学 2020-09-01 Balint Varga , Vince Grolmusz

This document has an unorthodox structure to accomplish an unorthodox goal: presenting the scaffolding for a zero-parameter Unified Theory of Life inside several dozen pages. Ideally, that length is short enough to be understood in a few…

神经元与认知 · 定量生物学 2018-01-03 William R. Softky

We are developing a system for human-robot communication that enables people to communicate with robots in a natural way and is focused on solving problems in a shared space. Our strategy for developing this system is fundamentally…

人机交互 · 计算机科学 2017-10-03 Michael Wollowski , Carlotta Berry , Ryder Winck , Alan Jern , David Voltmer , Alan Chiu , Yosi Shibberu

Diverse subfields of neuroscience have enriched artificial intelligence for many decades. With recent advances in machine learning and artificial neural networks, many neuroscientists are partnering with AI researchers and machine learning…

神经元与认知 · 定量生物学 2019-12-03 Thomas Dean , Chaofei Fan , Francis E. Lewis , Megumi Sano

The State of Brain Emulation Report 2025 provides a comprehensive reassessment of the field's progress since Sandberg and Bostrom's 2008 Whole Brain Emulation roadmap. The report is organized around three core capabilities required for…

神经元与认知 · 定量生物学 2025-11-06 Niccolò Zanichelli , Maximilian Schons , Isaak Freeman , Philip Shiu , Anton Arkhipov

Human routines structure daily life, yet remain challenging for computational systems to understand. This paper presents the first systematic review of routine computing, a previously implicit but increasingly recognized field that focuses…

人机交互 · 计算机科学 2026-04-27 Borislav Pavlov , Jiajin Li , Jun Fang , Yuntao Wang , Yuanchun Shi

Does the energy requirements for the human brain give energy constraints that give reason to doubt the feasibility of artificial intelligence? This report will review some relevant estimates of brain bioenergetics and analyze some of the…

人工智能 · 计算机科学 2016-02-15 Anders Sandberg

Neuroscientists today can measure activity from more neurons than ever before, and are facing the challenge of connecting these brain-wide neural recordings to computation and behavior. Here, we first describe emerging tools and…

神经元与认知 · 定量生物学 2022-01-10 Anne E. Urai , Brent Doiron , Andrew M. Leifer , Anne K. Churchland

Recent breakthroughs in artificial intelligence (AI) are reshaping the way we construct computational counterparts of the brain, giving rise to a new class of ``surrogate brains''. In contrast to conventional hypothesis-driven biophysical…

神经元与认知 · 定量生物学 2025-10-14 Yinuo Zhang , Demao Liu , Zhichao Liang , Jiani Cheng , Kexin Lou , Jinqiao Duan , Ting Gao , Bin Hu , Quanying Liu

Brain computer interfaces (BCI) provide a direct communication link between the brain and a computer or other external devices. They offer an extended degree of freedom either by strengthening or by substituting human peripheral working…

Humans and animals excel in combining information from multiple sensory modalities, controlling their complex bodies, adapting to growth, failures, or using tools. These capabilities are also highly desirable in robots. They are displayed…

机器人学 · 计算机科学 2022-11-08 Matej Hoffmann

New technologies have enabled the investigation of biology and human health at an unprecedented scale and in multiple dimensions. These dimensions include a myriad of properties describing genome, epigenome, transcriptome, microbiome,…

定量方法 · 定量生物学 2018-10-22 Marinka Zitnik , Francis Nguyen , Bo Wang , Jure Leskovec , Anna Goldenberg , Michael M. Hoffman

This chapter sheds light on the synaptic organization of the brain from the perspective of computational neuroscience. It provides an introductory overview on how to account for empirical data in mathematical models, implement such models…

Cognitive engineering is a multi-disciplinary field and hence it is difficult to find a review article consolidating the leading developments in the field. The in-credible pace at which technology is advancing pushes the boundaries of what…

人工智能 · 计算机科学 2016-11-01 Jarryd Son , Amit Kumar Mishra