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Recent advances in molecular and genetic research have identified a diverse range of brain tumor sub-types, shedding light on differences in their molecular mechanisms, heterogeneity, and origins. The present study performs whole-brain…

神经元与认知 · 定量生物学 2024-07-26 Debanjali Bhattacharya , Ninad Aithal , Manish Jayswal , Neelam Sinha

Diffusion magnetic resonance imaging (dMRI) tractography is an advanced imaging technique that enables in vivo mapping of the brain's white matter connections at macro scale. Over the last two decades, the study of brain connectivity using…

Recent developments in network neuroscience have highlighted the importance of developing techniques for analyzing and modeling brain networks. A particularly powerful approach for studying complex neural systems is to formulate generative…

神经元与认知 · 定量生物学 2022-09-09 Viplove Arora , Enrico Amico , Joaquín Goñi , Mario Ventresca

Large-scale white matter pathways crisscrossing the cortex create a complex pattern of connectivity that underlies human cognitive function. Generative mechanisms for this architecture have been difficult to identify in part because little…

神经元与认知 · 定量生物学 2015-06-16 Florian Klimm , Danielle S. Bassett , Jean M. Carlson , Peter J. Mucha

Understanding brain dynamics and functions critically depends on knowledge of the network connectivity among neurons. However, the complexity of brain structural connectivity, coupled with continuous modifications driven by synaptic…

神经元与认知 · 定量生物学 2025-07-04 Kai Chen , Mingzhang Wang , Songting Li , Douglas Zhou

We present a continuous model for structural brain connectivity based on the Poisson point process. The model treats each streamline curve in a tractography as an observed event in connectome space, here a product space of cortical white…

神经元与认知 · 定量生物学 2018-11-07 Daniel Moyer , Boris A. Gutman , Joshua Faskowitz , Neda Jahanshad , Paul M. Thompson

The white-matter (micro-)structural architecture of the brain promotes synchrony among neuronal populations, giving rise to richly patterned functional connections. A fundamental problem for systems neuroscience is determining the best way…

神经元与认知 · 定量生物学 2022-11-15 Yueting Li , Qingyue Wei , Ehsan Adeli , Kilian M. Pohl , Qingyu Zhao

Recent neuroimaging studies have shown that functional connectomes are unique to individuals, i.e., two distinct fMRIs taken over different sessions of the same subject are more similar in terms of their connectomes than those from two…

计算机视觉与模式识别 · 计算机科学 2019-08-12 Vikram Ravindra , Petros Drineas , Ananth Grama

The connectomes of different human brains are pairwise distinct: we cannot talk about an abstract "graph of the brain". Two typical connectomes, however, have quite a few common graph edges that may describe the same connections between the…

神经元与认知 · 定量生物学 2015-01-07 Balazs Szalkai , Csaba Kerepesi , Balint Varga , Vince Grolmusz

The underlying anatomical structure is fundamental to the study of brain networks, but the role of brainstem from a structural perspective is not very well understood. We conduct a computational and graph-theoretical study of the human…

神经元与认知 · 定量生物学 2023-04-26 Salma Salhi , Youssef Kora , Gisu Ham , Hadi Zadeh Haghighi , Christoph Simon

This article focuses on the problem of studying shared- and individual-specific structure in replicated networks or graph-valued data. In particular, the observed data consist of $n$ graphs, $G_i, i=1,\ldots,n$, with each graph consisting…

统计计算 · 统计学 2018-04-13 Lu Wang , Zhengwu Zhang , David Dunson

Diffusion MRI tractography technique enables non-invasive visualization of the white matter pathways in the brain. It plays a crucial role in neuroscience and clinical fields by facilitating the study of brain connectivity and neurological…

计算机视觉与模式识别 · 计算机科学 2025-03-06 Yiqiong Yang , Yitian Yuan , Baoxing Ren , Ye Wu , Yanqiu Feng , Xinyuan Zhang

Non-invasive measurements of the human brain using magnetic resonance imaging (MRI) have significantly improved our understanding the brain's network organization by enabling measurement of anatomical connections between brain regions…

应用统计 · 统计学 2025-12-10 Keshav Motwani , Ali Shojaie , Ariel Rokem , Eardi Lila

Mapping of human brain structural connectomes via diffusion MRI offers a unique opportunity to understand brain structural connectivity and relate it to various human traits, such as cognition. However, head displacement during image…

神经元与认知 · 定量生物学 2024-09-13 Yizi Zhang , Meimei Liu , Zhengwu Zhang , David Dunson

Representational similarity metrics are fundamental tools in neuroscience and AI, yet we lack systematic comparisons of their discriminative power across model families. We introduce a quantitative framework to evaluate representational…

机器学习 · 计算机科学 2025-12-10 Jialin Wu , Shreya Saha , Yiqing Bo , Meenakshi Khosla

Our understanding of the structure of the brain and its relationships with human traits is largely determined by how we represent the structural connectome. Standard practice divides the brain into regions of interest (ROIs) and represents…

应用统计 · 统计学 2023-06-13 Rongjie Liu , Meng Li , David B. Dunson

Integrating structural and functional connectomes remains challenging because their relationship is non-linear and organized over nested modular hierarchies. We propose a hierarchical multiscale structure-function coupling framework for…

The anatomical structure of the brain can be observed via non-invasive techniques such as diffusion imaging. However, these are imperfect because they miss connections that are actually known to exist, especially long range…

神经元与认知 · 定量生物学 2015-02-25 Somwrita Sarkar , Sanjay Chawla , Donna Xu

Discovering community structure in complex networks is a mature field since a tremendous number of community detection methods have been introduced in the literature. Nevertheless, it is still very challenging for practioners to determine…

社会与信息网络 · 计算机科学 2021-04-15 Vinh-Loc Dao , Cécile Bothorel , Philippe Lenca

Functional connectivity estimates are highly sensitive to analysis choices and can be dominated by noise when the number of sampled time points is small relative to network dimensionality. This issue is particularly acute in fMRI, where…

无序系统与神经网络 · 物理学 2026-02-10 Izaro Fernandez-Iriondo , Antonio Jimenez-Marin , Jesus Cortes , Pablo Villegas