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The remarkable mechanical properties of spider silk, including its tensile strength and extensibility, are primarily governed by the repetitive regions of the proteins that constitute the fiber, the major ampullate spidroins (MaSps).…

机器学习 · 计算机科学 2025-10-23 Neeru Dubey , Elin Karlsson , Miguel Angel Redondo , Johan Reimegård , Anna Rising , Hedvig Kjellström

Spider silks are remarkable materials characterized by superb mechanical properties such as strength, extensibility and lightweightedness. Yet, to date, limited models are available to fully explore sequence-property relationships for…

材料科学 · 物理学 2023-10-20 Wei Lu , David L. Kaplan , Markus J. Buehler

A finite element simulation of the mechanical behaviour of woven textile materials at the scale of individual fibers is proposed in this paper. The aim of the simulation is to understand and identify phenomena involved at different scales…

软凝聚态物质 · 物理学 2008-12-18 Damien Durville

We deduce a microstructure inspired model for humidity and temperature effects on the mechanical response of spider silks, modelled as a composite material with a hard crystalline and a soft amorphous region. Water molecules decrease the…

软凝聚态物质 · 物理学 2021-06-08 Giuseppe Puglisi , Domenico De Tommasi , Vincenzo Fazio , Nicola Maria Pugno

We propose a general multiscale approach for the mechanical behavior of three-dimensional networks of macromolecules undergoing strain-induced unfolding. Starting from a (statistically based) energetic analysis of the macromolecule…

软凝聚态物质 · 物理学 2015-06-22 Domenico De Tommasi , Giuseppe Puglisi , Giuseppe Saccomandi

Multiscale phenomena exhibit complex structure-function relationships, and predicting their macroscopic behavior requires deducing differential equations at different scales. The complexity of these equations and the number of essential…

数学物理 · 物理学 2023-07-25 Vincenzo Fazio , Nicola Maria Pugno , Orazio Giustolisi , Giuseppe Puglisi

Constitutive models that describe the mechanical behavior of soft tissues have advanced greatly over the past few decades. These expert models are generalizable and require the calibration of a number of parameters to fit experimental data.…

定量方法 · 定量生物学 2021-07-13 Vahidullah Tac , Vivek D. Sree , Manuel K. Rausch , Adrian B. Tepole

State of the art research and treatment of biological tissues require accurate and efficient methods for describing their mechanical properties. Indeed, micromechanics motivated approaches provide a systematic method for elevating relevant…

软凝聚态物质 · 物理学 2012-05-04 Gal deBotton , Tal Oren

Proteins are regularly described with some general indices (mass fractal dimension, surface fractal dimension, entropy, enthalpy, free energies, hydrophobicity, denaturation temperature etc..), which are inherently statistical in nature.…

生物大分子 · 定量生物学 2009-07-02 Anirban Banerji , Indira Ghosh

1. Spatial memory plays a role in the way animals perceive their environments, resulting in memory-informed movement patterns that are observable to ecologists. Developing mathematical techniques to understand how animals use memory in…

定量方法 · 定量生物学 2022-02-17 Peter R. Thompson , Andrew E. Derocher , Mark A. Edwards , Mark A. Lewis

Advanced modern technology and industrial sustainability theme have contributed implementing composite materials for various industrial applications. Green composites are among the desired alternatives for the green products. However, to…

神经与进化计算 · 计算机科学 2024-04-12 Faris M. AL-Oqla , Hossam Faris , Maria Habib , Pedro A. Castillo-Valdivieso

Recent advances in deep learning frameworks have established valuable tools for analyzing the long-timescale behavior of complex systems such as proteins. Especially the inclusion of physical constraints, e.g. time-reversibility, was a…

定量方法 · 定量生物学 2021-12-22 Andreas Mardt , Frank Noé

Computer simulations can aid in understanding how collective materials properties emerge from interactions between simple constituents. Here, we introduce a coarse-grained model that enables simulation of networks of actin filaments, myosin…

生物物理 · 物理学 2018-12-07 Simon L. Freedman , Shiladitya Banerjee , Glen M. Hocky , Aaron R. Dinner

Purpose: From the myofibrils to the whole muscle scale, muscle micro-constituents exhibit passive and active mechanical properties, potentially coupled to electrical, chemical, and thermal properties. Experimental characterization of some…

医学物理 · 物理学 2024-06-25 Aude Loumeaud , Philippe Pouletaut , Sabine Bensamoun , Daniel George , Simon Chatelin

Mechanical characterization of protein molecules has played a role on gaining insight into the biological functions of proteins, since some proteins perform the mechanical function. Here, we present the mesoscopic model of biological…

生物大分子 · 定量生物学 2008-07-18 Gwonchan Yoon , Hyung-Jin Park , Sungsoo Na , Kilho Eom

One of the essential questions in the area of granular matter is, how to obtain macroscopic tensorial quantities like stress and strain from ``microscopic'' quantities like the contact forces in a granular assembly. Different averaging…

统计力学 · 物理学 2007-05-23 Marc Lätzel , Stefan Luding , Hans J. Herrmann

We introduce an individual-based model for fiber elements having the ability to cross-link or unlink each other and to align with each other at the cross links. We first formally derive a kinetic model for the fiber and cross-links…

数学物理 · 物理学 2015-05-20 Pierre Degond , Fanny Delebecque , Diane Peurichard

Skeletal muscles are living tissues that can undergo large deformations in short periods of time and that can be activated to produce force. In this paper we use the principles of continuum mechanics to propose a dynamic, fully non-linear,…

Through evolution, nature has presented a set of remarkable protein materials, including elastins, silks, keratins and collagens with superior mechanical performances that play crucial roles in mechanobiology. However, going beyond natural…

材料科学 · 物理学 2023-12-19 Bo Ni , David L. Kaplan , Markus J. Buehler

An approach to the mechanical behaviour of textile composites at the scale of their constituting fibres, using an implicit finite element simulation code, is proposed in this chapter. The approach is based on efficient methods and…

综合物理 · 物理学 2012-01-24 Damien Durville
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